Anti-obesity and hypolipidemic effects of a functional formula containing Prumus mume in mice fed high-fat diet

African Journal of Biotechnology

Volumn 9, Issue 16, 2010, Pages 2463-2467

  Xia, Daozong ^a,b   Wu, Xiaoqin ^a   Yang, Qing ^b   Gong, Jinyan ^a   Zhang, Ying ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Anti obesity functional formula; High fat diet; L carnitine; Prunus mume

Indexed keywords

CARNITINE; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLANT EXTRACT; PRUNUS MUME EXTRACT; TETRAHYDROLIPSTATIN; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; HISTOPATHOLOGY; HYPERLIPIDEMIA; LIPID DIET; LIVER; MALE; MOUSE; NONHUMAN; OBESITY; PRUNUS; PRUNUS MUME; WEIGHT REDUCTION;

MUS; PRUNUS MUME;

EID: 77951705171     PISSN: 16845315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Adachi M, Suzuki Y, Mizuta T, Osawa T, Adachi T, Osaka K, Suzuki K, Shiojima K, Arai Y, Masuda K, Uchiyama M, Oyamada T, Clerici M (2007). The Prunus mume Sieb. et Zucc (Ume) is a rich natural source of novel anti-cancer substance. Int. J. Food Prop. 10: 375-384.
2. Bagri P, Ali M, Aeri V, Bhowmik M, Sultana S (2009). Antidiabetic effect of Punica granatum flowers: Effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes. Food Chem. Toxicol. 47: 62-69.
3. Choi H, Eo H, Park K, Jin M, Park EJ, Kim SH, Park JE, Kim S (2007). A water-soluble extract from Cucurbita moschata shows anti-obesity effects by controlling lipid metabolism in a high fat diet-induced obesity mouse model. Biochem. Biophys. Res. Commun. 359: 419-425.
4. Ekanem AP, Wang M, Simon JE, Moreno DA (2007). Antiobesity properties of two african plants (Afromomum meleguetta and Spilanthes acmella) by pancreatic lipase inhibition. Phytother. Res. 21: 1253-1255.
5. Ellrichmann M, Kapelle M, Ritter PR, Holst JJ, Herzig KH, Schmidt WE, Schmitz F, Meier JJ (2008). Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations. J. Clin. Endocrinol. Metab. 93: 3995-3998.
6. Friedewald WT, Levy RI, Fredrickson DS (1972). Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18: 499-502.
7. Hu JN, Zhu XM, Han LK, Saito M, Sun YS, Yoshikawa M, Kimura Y, Zheng YN (2008). Anti-obesity effects of escins extracted from the seeds of Aesculus turbinata Blume (Hippocastanaceae). Chem. Pharm. Bull. 56: 12-16.
8. Jimoh FO, Sofidiya MO, Afolayan AJ (2007). Antioxidant properties of the methanol extracts from the leaves of Paullinia pinnata. J. Med. Food. 10: 707-711.
9. Jo SC, Nam KC, Min BR, Ahn DU, Cho SH, Park WP, Lee SC (2006). Antioxidant activity of Prunus mume extract in cooked chicken breast meat. Int. J. Food Sci. Technol. 41: 15-19.
10. Kim YJ, Kim KY, Kim MS, Lee JH, Lee KP, Park T (2008). A mixture of the aqueous extract of Garcinia cambogia, soy peptide and L:-carnitine reduces the accumulation of visceral fat mass in rats rendered obese by a high fat diet. Genes Nutr. 2: 353-358.
11. Lee J, Chae K, Ha J, Park BY, Lee HS, Jeong S, Kim MY, Yoon M (2008). Regulation of obesity and lipid disorders by herbal extracts from Morus alba, Melissa officinalis, and Artemisia capillaris in high-fat diet-induced obese mice. J. Ethnopharm. 115: 263-270.
12. Lee MS, Lee HJ, Lee HS, Kim Y (2006). L-Carnitine stimulates lipolysis via induction of the lipolytic gene expression and suppression of the adipogenic gene expression in 3T3-L1 adipocytes. J. Med. Food. 9: 468-473.
13. Matsuda H, Morikawa T, Ishiwada T, Managi H, Kagawa M, Higashi Y, Yoshikawa M (2003). Medicinal flowers. VIII. Radical scavenging constituents from the flowers of Prunus mume: structure of prunose III. Chem. Pharm. Bull. 54: 440-443.
14. Ng CC, Lin CY, Tzeng WS, Chang CC, Shyu YT (2005). Establishment of an internal transcribed spacer (ITS) sequence-based differentiation identification procedure for mei (Prunus mume) and plum (Prunus salicina) and its use to detect adulteration in preserved fruits. Food Res. Intern. 38: 95-101.
15. Ning GG, Bai SP, Bao MZ, Liu L (2007). Factors affecting plantlet regeneration from in vitro cultured immature embryos and cotyledons of Prunus mume Xue mei. In vitro Cell Dev. Biol. Plant. 43: 95-100.
16. Ono Y, Hattori E, Fukaya Y, Imai S, Ohizumi Y (2006). Anti-obesity effect of Nelumbo nucifera leaves extract in mice and rats. J. Ethnopharm. 106: 238-244.
17. Pourmorad F, Hosseinimehr SJ, Shahabimajd N (2006). Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. Afr. J. Biotech. 5: 1142-1145.
18. Ryu JH, Ahn H, Kim JY, Kim YK (2003). Inhibitory activity of plant extracts on nitric oxide synthesis in LPS-activated macrophages. Phytother. Res. 17: 485-489.
19. Shrestha S, Bhattarai BR, Lee KH, Cho H (2007). Mono- and disalicylic acid derivatives: PTP1B inhibitors as potential anti-obesity drugs. Bioorg. Med. Chem. 15: 6535-6548.
20. Woo MN, Bok SH, Lee MK, Kim HJ, Jeon SM, Do GM, Shin SK, Ha TY, Choi MS (2008). Anti-obesity and hypolipidemic effects of a proprietary herb and fiber combination (SandS PWH) in rats fed high-fat diets. J. Med. Food. 11: 169-178.
21. Yang JY, Lee SJ, Park HW, Cha YS (2006). Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl/6J mice fed a high-fat diet. J. Med. Food. 9: 459-467.