메뉴 건너뛰기




Volumn 160, Issue 2, 2010, Pages 283-291

Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrations

Author keywords

ADHD; Atomoxetine; Glutamate metabolism; NMDA receptor; Transporter inhibitor; Whole cell patch clamp

Indexed keywords

ATOMOXETINE; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

EID: 77951695580     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.00707.x     Document Type: Article
Times cited : (63)

References (37)
  • 1
    • 40949095655 scopus 로고    scopus 로고
    • Guide to Receptors and Channels (GRAC), 3rd edition
    • DOI 10.1038/sj.bjp.0707746, PII 0707746
    • Alexander SPH, Mathie A, Peters JA (2008). Guide to Receptors and Channels (GRAC), 3rd edition. Br J Pharmacol 153 (Suppl. 2 S1 S209. (Pubitemid 351415518)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.SUPPL. 2
    • Alexander, S.P.H.1    Mathie, A.2    Peters, J.A.3
  • 2
    • 0023804977 scopus 로고
    • Voltage-dependent block by strychnine of N-Methyl-D-Aspartic-acid- activated cationic channels in rat cortical neurons in culture
    • Bertolino M, Vicini S (1988). Voltage-dependent block by strychnine of N-Methyl-D-Aspartic-acid-activated cationic channels in rat cortical neurons in culture. Mol Pharmacol 34 : 98 103.
    • (1988) Mol Pharmacol , vol.34 , pp. 98-103
    • Bertolino, M.1    Vicini, S.2
  • 3
    • 22144455050 scopus 로고    scopus 로고
    • Attention-deficit hyperactivity disorder
    • DOI 10.1016/S0140-6736(05)66915-2, PII S0140673605669152
    • Biederman J, Faraone SV (2005). Attention-deficit hyperactivity disorder. Lancet 366 : 237 248. (Pubitemid 40981053)
    • (2005) Lancet , vol.366 , Issue.9481 , pp. 237-248
    • Biederman, J.1    Faraone, S.V.2
  • 6
    • 23944511459 scopus 로고    scopus 로고
    • Pharmacological implications of two distinct mechanisms of interaction of memantine with N-Methyl-D-aspartate-gated channels
    • Chen HS, Lipton SA (2005). Pharmacological implications of two distinct mechanisms of interaction of memantine with N-Methyl-D-aspartate-gated channels. J Pharmacol Exp Ther 314 : 961 971.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 961-971
    • Chen, H.S.1    Lipton, S.A.2
  • 7
  • 11
    • 33947375667 scopus 로고    scopus 로고
    • A pilot evaluation of the safety, tolerability, pharmacokinetics, and effectiveness of memantine in pediatric patients with attention-deficit/ hyperactivity disorder combined type
    • DOI 10.1089/cap.2006.0044
    • Findling RL, McNamara NK, Stansbrey RJ, Maxhimer R, Periclou A, Mann A et al 2007b). A pilot evaluation of the safety, tolerability, pharmacokinetics, and effectiveness of memantine in pediatric patients with attention-deficit/ hyperactivity disorder combined type. J Child Adolesc Psychopharmacol 17 : 19 33. (Pubitemid 46452079)
    • (2007) Journal of Child and Adolescent Psychopharmacology , vol.17 , Issue.1 , pp. 19-33
    • Findling, R.L.1    McNamara, N.K.2    Stansbrey, R.J.3    Maxhimer, R.4    Periclou, A.5    Mann, A.6    Graham, S.M.7
  • 12
    • 30944446392 scopus 로고    scopus 로고
    • Comparison of the inhibitory and excitatory effects of ADHD medications methylphenidate and atomoxetine on motor cortex
    • Gilbert DL, Ridel KR, Sallee FR, Zahng J, Lipps TD, Wassermann EM (2006). Comparison of the inhibitory and excitatory effects of ADHD medications methylphenidate and atomoxetine on motor cortex. Neuropsychopharmacology 31 : 442 449.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 442-449
    • Gilbert, D.L.1    Ridel, K.R.2    Sallee, F.R.3    Zahng, J.4    Lipps, T.D.5    Wassermann, E.M.6
  • 13
    • 0024551137 scopus 로고
    • Experimental observations on the development of polarity by hippocampal neurons in culture
    • DOI 10.1083/jcb.108.4.1507
    • Goslin K, Banker G (1989). Experimental observations on the development of polarity by hippocampal neurons in culture. J Cell Biol 108 : 1507 1516. (Pubitemid 19097054)
    • (1989) Journal of Cell Biology , vol.108 , Issue.4 , pp. 1507-1516
    • Goslin, K.1    Banker, G.2
  • 14
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • DOI 10.1007/BF00656997
    • Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981). Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391 : 85 100. (Pubitemid 11012976)
    • (1981) Pflugers Archiv European Journal of Physiology , vol.391 , Issue.2 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3
  • 15
    • 58149465392 scopus 로고    scopus 로고
    • N-methyl-d-aspartate receptor subunit dysfunction at hippocampal glutamatergic synapses in an animal model of attention-deficit/hyperactivity disorder
    • Jensen V, Rinholm JE, Johansen TJ, Medin T, Storm-Mathisen J, Sagvolden T et al 2009). N-methyl-d-aspartate receptor subunit dysfunction at hippocampal glutamatergic synapses in an animal model of attention-deficit/hyperactivity disorder. Neuroscience 158 : 353 364.
    • (2009) Neuroscience , vol.158 , pp. 353-364
    • Jensen, V.1    Rinholm, J.E.2    Johansen, T.J.3    Medin, T.4    Storm-Mathisen, J.5    Sagvolden, T.6
  • 16
    • 58149467009 scopus 로고    scopus 로고
    • Microdialysis evaluation of atomoxetine brain penetration and central nervous system pharmacokinetics in rats
    • Kielbasa W, Kalvass JC, Stratford R (2009). Microdialysis evaluation of atomoxetine brain penetration and central nervous system pharmacokinetics in rats. Drug Metab Dispos 37 : 137 142.
    • (2009) Drug Metab Dispos , vol.37 , pp. 137-142
    • Kielbasa, W.1    Kalvass, J.C.2    Stratford, R.3
  • 18
    • 0029843314 scopus 로고    scopus 로고
    • Etiology and pathogenesis of attention-deficit hyperactivity disorder (ADHD): Significance of prematurity and perinatal hypoxic-haemodynamic encephalopathy
    • Lou HC (1996). Etiology and pathogenesis of attention-deficit hyperactivity disorder (ADHD): significance of prematurity and perinatal hypoxic-haemodynamic encephalopathy. Acta Paediatr 85 : 1266 1271.
    • (1996) Acta Paediatr , vol.85 , pp. 1266-1271
    • Lou, H.C.1
  • 19
    • 43049163841 scopus 로고    scopus 로고
    • Neurodevelopmental and neurodegenerative diseases - Is there a pathophysiological link? Attention-deficit/hyperactivity disorder and amyotrophic lateral sclerosis as examples
    • Lulé D, Ludolph AC, Ludolph AG (2008). Neurodevelopmental and neurodegenerative diseases - Is there a pathophysiological link? Attention-deficit/hyperactivity disorder and amyotrophic lateral sclerosis as examples. Med Hypotheses 70 : 1133 1138.
    • (2008) Med Hypotheses , vol.70 , pp. 1133-1138
    • Lulé, D.1    Ludolph, A.C.2    Ludolph, A.G.3
  • 21
    • 67650280749 scopus 로고    scopus 로고
    • The MTA at 8 years: Prospective follow-up of children treated for combined type ADHD in a multisite study
    • Althe Mta Cooperative Group
    • Molina BS, Hinshaw SP, Swanson JM, Arnold LE, Vitiello B, Jensen PS et al the MTA Cooperative Group (2009). The MTA at 8 years: prospective follow-up of children treated for combined type ADHD in a multisite study. J Am Acad Child Adolesc Psychiatry 48 : 484 500.
    • (2009) J Am Acad Child Adolesc Psychiatry , vol.48 , pp. 484-500
    • Molina, B.S.1    Hinshaw, S.P.2    Swanson, J.M.3    Arnold, L.E.4    Vitiello, B.5    Jensen, P.S.6
  • 22
    • 0028343648 scopus 로고
    • Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
    • DOI 10.1016/0896-6273(94)90210-0
    • Monyer H, Burnashev N, Laurie DJ, Sakmann B, Seeburg PH (1994). Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12 : 529 540. (Pubitemid 24100885)
    • (1994) Neuron , vol.12 , Issue.3 , pp. 529-540
    • Monyer, H.1    Burnashev, N.2    Laurie, D.J.3    Sakmann, B.4    Seeburg, P.H.5
  • 24
    • 0026419327 scopus 로고
    • Molecular cloning and characterization of the rat NMDA receptor
    • Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S (1991). Molecular cloning und characterization of the rat NMDA receptor. Nature 354 : 31 37. (Pubitemid 21896774)
    • (1991) Nature , vol.354 , Issue.6348 , pp. 31-37
    • Moriyoshi, K.1    Masu, M.2    Ishii, T.3    Shigemoto, R.4    Mizuno, N.5    Nakanishi, S.6
  • 25
    • 36549030795 scopus 로고    scopus 로고
    • Stress, depression, and neuroplasticity: A convergence of mechanisms
    • Pittenger C, Duman RS (2008). Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology 33 : 88 109.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 88-109
    • Pittenger, C.1    Duman, R.S.2
  • 26
    • 34250832736 scopus 로고    scopus 로고
    • The worldwide prevalence of ADHD: A systematic review and metaregression analysis
    • DOI 10.1176/appi.ajp.164.6.942
    • Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA (2007). The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry 164 : 942 948. (Pubitemid 46972911)
    • (2007) American Journal of Psychiatry , vol.164 , Issue.6 , pp. 942-948
    • Polanczyk, G.1    De Lima, M.S.2    Horta, B.L.3    Biederman, J.4    Rohde, L.A.5
  • 30
    • 0024625331 scopus 로고
    • Open channel block of NMDA receptor responses evoked by tricyclic antidepressants
    • Sernagor E, Kuhn D, Vyklicky L, Mayer ML (1989). Open channel block of NMDA receptor responses evoked by tricyclic antidepressants. Neuron 2 : 1221 1227.
    • (1989) Neuron , vol.2 , pp. 1221-1227
    • Sernagor, E.1    Kuhn, D.2    Vyklicky, L.3    Mayer, M.L.4
  • 31
    • 0033841786 scopus 로고    scopus 로고
    • The trapping block of NMDA receptor channels in acutely isolated rat hippocampal neurones
    • Sobolevsky AI, Yelshansky MV (2000). The trapping block of NMDA receptor channels in acutely isolated rat hippocampal neurons. J Physiol 526 : 493 506. (Pubitemid 30649613)
    • (2000) Journal of Physiology , vol.526 , Issue.3 , pp. 493-506
    • Sobolevsky, A.I.1    Yelshansky, M.V.2
  • 32
    • 33646467730 scopus 로고    scopus 로고
    • Effect of the attention deficit/hyperactivity disorder drug atomoxetine on extracellular concentrations of norepinephrine and dopamine in several brain regions of the rat
    • Swanson CJ, Perry KW, Koch-Krueger S, Katner J, Svensson KA, Bymaster FP (2006). Effect of the attention deficit/hyperactivity disorder drug atomoxetine on extracellular concentrations of norepinephrine and dopamine in several brain regions of the rat. Neuropharmacology 50 : 755 760.
    • (2006) Neuropharmacology , vol.50 , pp. 755-760
    • Swanson, C.J.1    Perry, K.W.2    Koch-Krueger, S.3    Katner, J.4    Svensson, K.A.5    Bymaster, F.P.6
  • 33
    • 35848941499 scopus 로고    scopus 로고
    • Direct inhibitory effect of fluoxetine on n-methyl-d-aspartate receptors in the central nervous system
    • DOI 10.1016/j.biopsych.2007.04.014, PII S0006322307003642, Depression: New Perspectives on Treatment and Etiology
    • Szasz BK, Mike A, Karoly R, Gerevich Z, Illes P, Vizi ES et al 2007). Direct inhibitory effect of fluoxetine on n-methyl-d-aspartate receptors in the central nervous system. Biol Psychiatry 62 : 1303 1309. (Pubitemid 350060896)
    • (2007) Biological Psychiatry , vol.62 , Issue.11 , pp. 1303-1309
    • Szasz, B.K.1    Mike, A.2    Karoly, R.3    Gerevich, Z.4    Illes, P.5    Vizi, E.S.6    Kiss, J.P.7
  • 34
    • 11444257874 scopus 로고    scopus 로고
    • The acute effect of methylphenidate in Brazilian male children and adolescents with ADHD: A randomized clinical trial
    • Szobot CM, Ketzer C, Parente MA, Biederman J, Rohde LA (2004). The acute effect of methylphenidate in Brazilian male children and adolescents with ADHD: a randomized clinical trial. J Atten Disord 8 : 37 43. (Pubitemid 40081858)
    • (2004) Journal of Attention Disorders , vol.8 , Issue.2 , pp. 37-43
    • Szobot, C.M.1    Ketzer, C.2    Parente, M.A.3    Biederman, J.4    Rohde, L.A.5
  • 36
    • 0015879604 scopus 로고
    • Ionic blockage of sodium channels in nerve
    • Woodhull AM (1973). Ionic blockage of sodium channels in nerve. J Gen Physiol 61 : 687 708.
    • (1973) J Gen Physiol , vol.61 , pp. 687-708
    • Woodhull, A.M.1
  • 37
    • 37849040160 scopus 로고    scopus 로고
    • 2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes
    • 2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. J Physiol 586 : 211 225.
    • (2008) J Physiol , vol.586 , pp. 211-225
    • Wrighton, D.C.1    Baker, E.J.2    Chen, P.E.3    Wyllie, D.J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.