Domino multicomponent michael - Michael - Aldol reactions under phase-transfer catalysis: Diastereoselective synthesis of pentasubstituted cyclohexanes

Synlett

Volumn , Issue 1, 2010, Pages 115-118

  Resende, Diana I S P ^a   Oliva, Cristina G ^a   Silva, Artur M S ^a   Almeida Paz, Filipe A ^b   Cavaleiro, José A S ^a  

^a UNIVERSITY OF AVEIRO   (Portugal)

^b UNIVERSITY OF AVEIRO   (Portugal)

Author keywords

Diastereoselectivity; Domino reaction; Multicomponent reaction; Phasetransfer catalysis

Indexed keywords

CYCLOHEXANE DERIVATIVE;

ALDOL REACTION; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; MICHAEL ADDITION; ONE POT SYNTHESIS; PHASE TRANSITION; STEREOCHEMISTRY; SYNTHESIS;

EID: 77951678632     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0029-1218523     Document Type: Article

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37. 3,20 °C): δ = 124.8 (C-2), 126.7 (C-5), 127.4 (C-2″,6″), 128.9 (C-3′,5′, C-3″,5″), 129.4 (C-4″), 129.8 (C-2′,6′), 136.0 (C-1″), 136.5 (C-1′), 139.1 (C-4′), 142.4 (C-4), 145.4 (C-3), 189.1 (C-I) ppm. Anal. Caled: C, 75.98; H, 4.88. Found: C, 75.92; H, 4.86.
38. +: 552.2145; found: 552.2147. Anal. Caicd: C, 79.37; H, 5.90; N, 2.64. Found: C, 78.97; H, 5.91; N, 2.73. (Figure Presented)
39. int = 0.0843). Final A1 = 0.0588 [I > Iσ(I)] and wR2 = 0.1497 (all data). CCDC-743412 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data request/cif.
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