Effect of a small molecule BCL-2 inhibitor on immune function and use with a recombinant vaccine

International Journal of Cancer

Volumn 127, Issue 7, 2010, Pages 1603-1613

  Farsaci, Benedetto ^a   Sabzevari, Helen ^a   Higgins, Jack P ^a   Di Bari, Maria Giovanna ^a   Takai, Shinji ^a   Schlom, Jeffrey ^a   Hodge, James W ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

GX15 070; Lung cancer; Small molecule inhibitor; Tumor immunotherapy; Vaccine

Indexed keywords

FOWLPOX VACCINE; OBATOCLAX; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT VACCINE; UNCLASSIFIED DRUG; CANCER VACCINE; HERMES ANTIGEN; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; FEMALE; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LUNG CARCINOMA; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; TUMOR ASSOCIATED LEUKOCYTE; VACCINATION; ADENOCARCINOMA; ANIMAL; C57BL MOUSE; CELL CYCLE; DRUG ANTAGONISM; FLOW CYTOMETRY; IMMUNOBLOTTING; IMMUNOLOGY; LUNG TUMOR; LYMPHOCYTE ACTIVATION; PATHOLOGY;

ADENOCARCINOMA; ANIMALS; ANTIGENS, CD44; CANCER VACCINES; CD8-POSITIVE T-LYMPHOCYTES; CELL CYCLE; FLOW CYTOMETRY; IMMUNOBLOTTING; LUNG NEOPLASMS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; PROTO-ONCOGENE PROTEINS C-BCL-2; T-LYMPHOCYTES, REGULATORY; VACCINES, SYNTHETIC;

EID: 77951677174     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25177     Document Type: Article

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