Comparison of nitric oxide donors in lowering intraocular pressure in rabbits: Role of cyclic GMP

Journal of Ocular Pharmacology and Therapeutics

Volumn 18, Issue 1, 2002, Pages 11-23

  Moilanen, Eeva ^c   Alajuuma, PÄivi ^b   SalmenperÄ, Pertteli ^a   Olli, Oksala ^b   Laippala, Pekka ^d   Heikki, Vapaatalo ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b Santen Oy   (Finland)

^c UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

^d TAMPERE UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; 8 BROMO CYCLIC GMP; ARGININE; ATRIOPEPTIN II; ATRIOPEPTIN III; CYCLIC GMP; N [4 [1 (3 AMINOPROPYL) 2 HYDROXY 2 NITROSOHYDRAZINO]BUTYL] 1,3 PROPANEDIAMINE; NITRATE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NITRITE; NITROPRUSSIDE SODIUM; S NITROSOCAPTOPRIL; S NITROSOTHIOL; UNCLASSIFIED DRUG; ZAPRINAST;

ANIMAL EXPERIMENT; AQUEOUS HUMOR; ARTICLE; BLOOD LEVEL; CILIARY BODY; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GLAUCOMA; INTRAOCULAR HYPOTENSION; INTRAOCULAR PRESSURE; MALE; NONHUMAN; PROTEIN EXPRESSION; RABBIT; TOPICAL ANESTHESIA; TREATMENT OUTCOME; WESTERN BLOTTING;

ANIMALS; ARGININE; CYCLIC GMP; FEMALE; INDAZOLES; INTRAOCULAR PRESSURE; MALE; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; PURINONES; RABBITS;

EID: 0036166985     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/108076802317233171     Document Type: Article

References (36)

1. Nitric oxide: Physiology, pathophysiology and pharmacology
2. The use of nitric oxide donors in pharmacological studies
3. Nitric oxide as a signaling molecule in the vascular system: An overview
4. Nitric oxide
5. Functional role of nitric oxide in regulation of ocular blood flow
6. Nitric oxide in the eye: Multifaceted roles and diverse outcomes
7. Nitric oxide and nitrovasodilators in the eye: Implications for ocular physiology and glaucoma
8. New approaches to antiglaucoma therapy
9. Atrial natriuretic peptides-effects on intraocular pressure, cGMP, and aqueous flow
10. Nitrovasodilators as a new class of ocular hypotensive agents
11. Nanogram nitrite and nitrate determination in environmental and biological materials by vanadium (III) reduction with chemiluminescence detection
12. Attomole sensitive radioimmunoassay for cyclic GMP
13. Protein measurement with the folin phenol reagent
14. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
15. Decreased intraocular pressure induced by nitric oxide donors is correlated to nitrite production in the rabbit eye
16. Nitrovasodilator effects on intraocular pressure and outflow facility in monkeys
17. Effect of the topical application of nitroglycerin on intraocular pressure in normal and glaucomatous monkeys
18. Sodium nitroprusside: Twenty years and counting
19. Actions of C-type natriuretic peptide and sodium nitroprusside on carbachol-stimulated inositol phosphate formation and contraction in ciliary and iris sphincter smooth muscles
20. In vitro comparison of two NONOates (novel nitric oxide donors) on rat pulmonary arteries
21. Ocular hypotensive effects of L-arginine and its derivatives and their actions on ocular blood flow
22. Effect of 8-Br-cGMP on aqueous humor dynamics in monkeys
23. Topical 8-bromo-cyclic GMP lowers intraocular pressure in rabbits
24. Effects of cyclic nucleotide analogs on intraocular pressure and trauma-induced inflammation in the rabbit eye
25. Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme
26. Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP and phosphodiesterase activity
27. A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor
28. Atriopeptin, sodium azide and cyclic GMP reduce secretion of aqueous humor and inhibit intracellular calcium release in bovine cultured ciliary epithelium
29. Synthetic atrial natriuretic factor lowers rabbit intraocular pressure
30. Atrial natriuretic peptide (ANP), guanylate cyclase, and intraocular pressure in the rabbit eye
31. Atriopeptin-activated guanylate cyclase in the anterior segment-identification, localization, and effects of atriopeptins on IOP
32. Sustained decreases in systemic blood pressure do not cause ocular hypotension
33. Negative feedback regulation of endothelial cell function by nitric oxide
34. Direct and reversible inhibition of endothelial nitric oxide synthase by nitric oxide
35. Inhibition by sodium nitroprusside of the expression of inducible nitric oxide synthase in rat neutrophils
36. cGMP-mediated negative-feedback regulation of endothelial nitric oxide synthase expression by nitric oxide