The Rowett rat strain is resistant to renal fibrosis

Nephrology Dialysis Transplantation

Volumn 25, Issue 5, 2010, Pages 1458-1462

  Kökény, Gábor ^a   Németh, Zalán ^a   Godó, Mária ^a   Hamar, Péter ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Glomerulosclerosis; Podocyte; Progression; Resistant strain

Indexed keywords

3 NITROTYROSINE; DESMIN; FIBRONECTIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DIET; DISEASE SEVERITY; GENETIC RESISTANCE; GLOMERULOSCLEROSIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFARCTION; KIDNEY FIBROSIS; KIDNEY FUNCTION; MALE; NEPHRECTOMY; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN DIET; PROTEINURIA; RAT; RENAL PROTECTION; SENSITIVITY ANALYSIS; SPRAGUE DAWLEY RAT; STAINING;

ANIMALS; FIBRONECTINS; FIBROSIS; IMMUNOHISTOCHEMISTRY; KIDNEY; MALE; NEPHRECTOMY; PODOCYTES; RATS; RATS, SPRAGUE-DAWLEY; TRANSFORMING GROWTH FACTOR BETA;

EID: 77951670569     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfp689     Document Type: Article

References (41)

1. Rostand SG, Kirk KA, Rutsky EA, et al. Racial differences in the incidence of treatment for end-stage renal disease. N Engl J Med 1982; 306: 1276-1279 (Pubitemid 12100210)
2. Kaplan JM, Kim SH, North KN, et al. Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclero-sis. Nat Genet 2000; 24: 251-256
3. Fitzgibbon WR, Greene EL, Grewal JS, et al. Resistance to remnant nephropathy in the Wistar-Furth rat. J Am Soc Nephrol 1999; 10: 814-821
4. Fleck C, Appenroth D, Jonas P, et al. Suitability of 5/6 nephrectomy (5/6NX) for the induction of interstitial renal fibrosis in rats\influence of sex, strain, and surgical procedure. Exp Toxicol Pathol 2006; 57: 195-205 (Pubitemid 43061190)
5. Grond J, Beukers JY, Schilthuis MS, et al. Analysis of renal structural and functional features in two rat strains with a different susceptibility to glomerular sclerosis. Lab Invest 1986; 54: 77-83 (Pubitemid 16163880)
6. Grond J, Muller EW, van Goor H, et al. Differences in puromycin aminonucleoside nephrosis in two rat strains. Kidney Int 1988; 33: 524-529 (Pubitemid 18073777)
7. Aben JA, Hoogervorst DA, Paul LC, et al. Genes expressed by the kidney, but not by bone marrow-derived cells, underlie the genetic predisposition to progressive glomerulosclerosis after mesangial injury. J Am Soc Nephrol 2003; 14: 2264-2270
8. Brandis A, Bianchi G, Reale E, et al. Age-dependent glomerulo-sclerosis and proteinuria occurring in rats of the Milan normotensive strain and not in rats of the Milan hypertensive strain. Lab Invest 1986; 55: 234-243 (Pubitemid 16017549)
9. Sterzel RB, Luft FC, Gao Y, et al. Renal disease and the development of hypertension in salt-sensitive Dahl rats. Kidney Int 1988; 33: 1119-1129
10. Zheng Z, Schmidt-Ott KM, Chua S, et al. A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse. Proc Natl Acad Sci USA 2005; 102: 2502-2507 (Pubitemid 40279406)
11. Papeta N, Chan KT, Prakash S, et al. Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression. J Clin Invest 2009; 119: 1178-1188
12. Brenner BM, Meyer TW, Hostetter TH. Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glo-merular sclerosis in aging, renal ablation, and intrinsic renal disease. N Engl J Med 1982; 307: 652-659
13. Anderson S, Meyer TW, Rennke HG, et al. Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass. J Clin Invest 1985; 76: 612-619 (Pubitemid 15227525)
14. Fries JW, Sandstrom DJ, Meyer TW, et al. Glomerular hypertrophy and epithelial cell injury modulate progressive glomerulosclerosis in the rat. Lab Invest 1989; 60: 205-218
15. Nagata M, Kriz W. Glomerular damage after uninephrectomy in young rats. II. Mechanical stress on podocytes as a pathway to sclerosis. Kidney Int 1992; 42: 148-160
16. Floege J, Alpers CE, Burns MW, et al. Glomerular cells, extracellular matrix accumulation, and the development of glomerulosclerosis in the remnant kidney model. Lab Invest 1992; 66: 485-497
17. Ebihara I, Suzuki S, Nakamura T, et al. Extracellular matrix component mRNA expression in glomeruli in experimental focal glomeru-losclerosis. J Am Soc Nephrol 1993; 3: 1387-1397
18. Remuzzi G, Bertani T. Is glomerulosclerosis a consequence of altered glomerular permeability to macromolecules? Kidney Int 1990; 38: 384-394 (Pubitemid 20258739)
19. Remuzzi G, Bertani T. Pathophysiology of progressive nephropa-thies. N Engl J Med 1998; 339: 1448-1456
20. Kriz W, Gretz N, Lemley KV. Progression of glomerular diseases: is the podocyte the culprit?. Kidney Int 1998; 54: 687-697 (Pubitemid 28397387)
21. Olson JL, Hostetter TH, Rennke HG, et al. Altered glomerular perms-electivity and progressive sclerosis following extreme ablation of renal mass. Kidney Int 1982; 22: 112-126
22. Shimojo H. Adaptation and distortion of podocytes in rat remnant kidney. Pathol Int 1998; 48: 368-383 (Pubitemid 28355161)
23. Vaziri ND, Dicus M, Ho ND, et al. Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency. Kidney Int 2003; 63: 179-185 (Pubitemid 35463919)
24. Satoh M, Fujimoto S, Haruna Y, et al. NAD(P)H oxidase and uncoupled nitric oxide synthase are major sources of glomerular super-oxide in rats with experimental diabetic nephropathy. Am J Physiol Renal Physiol 2005; 288: F1144-F1152 (Pubitemid 40677084)
25. Szabo AJ, Wagner L, Erdely A, et al. Renal neuronal nitric oxide synthase protein expression as a marker of renal injury. Kidney Int 2003; 64: 1765-1771 (Pubitemid 37323705)
26. Magnotti RA Jr, Stephens GW, Rogers RK, et al. Microplate measurement of urinary albumin and creatinine. Clin Chem 1989; 35: 1371-1375
27. El Nahas AM, Zoob SN, Evans DJ, Rees AJ. Chronic renal failure after nephrotoxic nephritis in rats: contributions to progression. Kidney Int 1987; 32: 173-180 (Pubitemid 17130787)
28. Amann K, Rump LC, Simonaviciene A, et al. Effects of low dose sympathetic inhibition on glomerulosclerosis and albuminuria in subtotally nephrectomized rats. J Am Soc Nephrol 2000; 11: 1469-1478 (Pubitemid 30483463)
29. Buzello M, Haas CS, Hauptmann F, et al. No aggravation of renal injury in apolipoprotein E knockout mice (ApoE(-/-)) after subtotal nephrectomy. Nephrol Dial Transplant 2004; 19: 566-573 (Pubitemid 38263114)
30. Gross ML, El-Shakmak A, Szabo A, et al. ACE-inhibitors but not endothelin receptor blockers prevent podocyte loss in early diabetic nephropathy. Diabetologia 2003; 46: 856-868 (Pubitemid 36831416)
31. Szabo AJ, Muller V, Chen GF, et al. Nephron number determines susceptibility to renal mass reduction-induced CKD in Lewis and Fisher 344 rats: implications for development of experimentally induced chronic allograft nephropathy. Nephrol Dial Transplant 2008; 23: 2492-2495
32. Griffin KA, Picken M, Bidani AK. Method of renal mass reduction is a critical modulator of subsequent hypertension and glomerular injury. J Am Soc Nephrol 1994; 4: 2023-2031 (Pubitemid 24977009)
33. Griffin KA, Picken MM, Churchill M, et al. Functional and structural correlates of glomerulosclerosis after renal mass reduction in the rat. J Am Soc Nephrol 2000; 11: 497-506 (Pubitemid 30115079)
34. Kocks MJA, van Goor H, de Zeeuw D, Navis G. High residual renal ACE during ACE inhibition and high sodium intake: cause or consequence of therapy resistance to ACE inhibition?. J Am Soc Nephrol 2002; 13: SA-P0372
35. Kagami S, Border WA, Miller DE, et al. Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest 1994; 93: 2431-2437 (Pubitemid 24177156)
36. Juknevicius I, Segal Y, Kren S, et al. Effect of aldosterone on renal transforming growth factor-beta. Am J Physiol Renal Physiol 2004; 286: F1059-F1062 (Pubitemid 38656360)
37. Eddy AA. Interstitial nephritis induced by protein-overload protein-uria. Am J Pathol 1989; 135: 719-733
38. Yaoita E, Kawasaki K, Yamamoto T, et al. Variable expression of desmin in rat glomerular epithelial cells. Am J Pathol 1990; 136: 899-908 (Pubitemid 20142325)
39. Zou J, Yaoita E, Watanabe Y, et al. Upregulation of nestin, vimentin, and desmin in rat podocytes in response to injury. Virchows Arch 2006; 448: 485-492
40. Floege J, Hackmann B, Kliem V, et al. Age-related glomerulosclerosis and interstitial fibrosis in Milan normotensive rats: a podocyte disease. Kidney Int 1997; 51: 230-243 (Pubitemid 27064542)
41. Hoshi S, Shu Y, Yoshida F, et al. Podocyte injury promotes progressive nephropathy in Zucker diabetic fatty rats. Lab Invest 2002; 82: 25-35 (Pubitemid 34072643)