Down-regulation of hypoxia inducible factor-1α: A possible explanation for the protective effects of estrogen on genioglossus fatigue resistance

European Journal of Oral Sciences

Volumn 118, Issue 2, 2010, Pages 139-144

  Jia, Shan Shan ^a   Liu, Yue Hua ^a  

^a TONGJI UNIVERSITY   (China)

Author keywords

Chronic intermittent hypoxia; Estrogen; Genioglossus; Hypoxia inducible factor 1

Indexed keywords

ESTROGEN; HIF1A PROTEIN, RAT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PROTECTIVE AGENT;

ANIMAL; ANOXIA; ARTICLE; COMPARATIVE STUDY; DISEASE MODEL; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; ELECTROSTIMULATION; HOMEOSTASIS; MALE; MUSCLE FATIGUE; MUSCLE ISOMETRIC CONTRACTION; MUSCLE TONE; OXYGEN CONSUMPTION; PATHOPHYSIOLOGY; PHENOTYPE; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; TIME; TONGUE; TRANSDUCER;

ANIMALS; ANOXIA; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ELECTRIC STIMULATION; ESTROGENS; HOMEOSTASIS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; ISOMETRIC CONTRACTION; MALE; MUSCLE FATIGUE; MUSCLE TONUS; OXYGEN CONSUMPTION; PHENOTYPE; PROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TIME FACTORS; TONGUE; TRANSDUCERS;

EID: 77951663470     PISSN: 09098836     EISSN: 16000722     Source Type: Journal    
DOI: 10.1111/j.1600-0722.2010.00712.x     Document Type: Article

References (43)

1. Malhotra A, White DP. Obstructive sleep apnoea. Lancet 2002, 360:237-245.
2. Bixler EO, Vgontzas AN, Lin HM, Ten Have T, Rein J, Vela-Bueno A, Kales A. Prevalence of sleep-disordered breathing in women: effects of gender. Am J Respir Crit Care Med 2001, 163:608-613.
3. Horner RL. The neuropharmacology of upper airway motor control in the awake and asleep states: implications for obstructive sleep apnoea. Respir Res 2001, 2:286-294.
4. Remmers JE, Degroot WJ, Sauerland EK, Anch AM. Pathogenesis of upper airway occlusion during sleep. J Appl Physiol 1978, 44:931-938.
5. Zamarron C, García Paz V, Riveiro A. Obstructive sleep apnea syndrome is a systemic disease. Current evidence. Eur J Intern Med 2008, 19:390-398.
6. O'halloran KD. Effects of nicotine on rat sternohyoid muscle contractile properties. Respir Physiol Neurobiol 2006, 150:200-210.
7. Owens RL, Eckert DJ, Yeh SY, Malhotra A. Upper airway function in the pathogenesis of obstructive sleep apnea: a review of the current literature. Curr Opin Pulm Med 2008, 14:519-524.
8. Mcguire M, Macdermott M, Bradford A. Effects of chronic episodic hypoxia on rat upper airway muscle contractile properties and fiber-type distribution. Chest 2002, 122:1012-1017.
9. O'halloran KD, Mcguire M, O'hare T, Bradford A. Chronic intermittent asphyxia impairs rat upper airway muscle responses to acute hypoxia and asphyxia. Chest 2002, 122:269-275.
10. Veasey SC, Zhan G, Fenik P, Pratico D. Long-term intermittent hypoxia: reduced excitatory hypoglossal nerve output. Am J Respir Crit Care Med 2004, 170:665-672.
11. Adams JM, Difazio LT, Rolandelli RH, Luján JJ, Haskó G, Csóka B, Selmeczy Z, Németh ZH. HIF-1: a key mediator in hypoxia. Acta Physiol Hung 2009, 96:19-28.
12. Packard MG, Teather LA. Posttraining estradiol injections enhance memory in ovariectomized rats: cholinergic blockade and synergism. Neurobiol Learn Mem 1997, 68:172-188.
13. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C (T)) method. Methods 2001, 25:402-408.
14. Martins AB, Tufik S, Moura SM. Physiopathology of obstructive sleep apnea-hypopnea syndrome. J Bras Pneumol 2007, 33:93-100.
15. Blumen MB, De La Sota AP, Quera-Salva MA, Frachet B, Chabolle F, Lofaso F. Tongue mechanical characteristics and genioglossus muscle EMG in obstructive sleep apnoea patients. Respir Physiol Neurobiol 2004, 140:155-164.
16. Dellorusso C, Khurana N, Rankin L, Sullivan J, Fregosi RF. Mechanisms of force failure during repetitive maximal efforts in a human upper airway muscle. Muscle Nerve 2002, 26:94-100.
17. O'donnell CP, Ayuse T, King ED, Schwartz AR, Smith PL, Robotham JL. Airway obstruction during sleep increases blood pressure without arousal. J Appl Physiol 1996, 80:773-781.
18. Rey S, Tarvainen MP, Karjalainen PA, Iturriaga R. Dynamic time-varying analysis of heart rate and blood pressure variability in cats exposed to short-term chronic intermittent hypoxia. Am J Physiol Regul Integr Comp Physiol 2008, 295:R28-R37.
19. Ma S, Mifflin SW, Cunningham JT, Morilak DA. Chronic intermittent hypoxia sensitizes acute hypothalamic-pituitary-adrenal stress reactivity and Fos induction in the rat locus coeruleus in response to subsequent immobilization stress. Neuroscience 2008, 154:1639-1647.
20. Li J, Grigoryev DN, Ye SQ, Thorne L, Schwartz AR, Smith PL, O'donnell CP, Polotsky VY. Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice. J Appl Physiol 2005, 99:1643-1648.
21. Fletcher EC. Invited review: physiological consequences of intermittent hypoxia: systemic blood pressure. J Appl Physiol 2001, 90:1600-1605.
22. McGuire M, Bradford A. Chronic intermittent hypoxia increases haematocrit and causes right ventricular hypertrophy in the rat. Respir Physiol 1999, 117:53-58.
23. Bradford A, McGuire M, O'halloran KD. Does episodic hypoxia affect upper airway dilator muscle function? Implications for the pathophysiology of obstructive sleep apnoea. Respir Physiol Neurobiol 2005, 147:223-234.
24. Hardie DG, Hawley SA, Scott JW. AMP-activated protein kinase--development of the energy sensor concept. J Physiol 2006, 574:7-15.
25. Bartrons R, Caro J. Hypoxia, glucose metabolism and the Warburg's effect. J Bioenerg Biomembr 2007, 39:223-229.
26. Mekhail K, Gunaratnam L, Bonicalzi ME, Lee S. HIF activation by pH-dependent nucleolar sequestration of VHL. Nat Cell Biol 2004, 6:642-647.
27. Stroka DM, Burkhardt T, Desbaillets I, Wenger RH, Neil DA, Bauer C, Gassmann M, Candinas D. HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J 2001, 15:2445-2453.
28. Mason S, Johnson RS. The role of HIF-1 in hypoxic response in the skeletal muscle. Adv Exp Med Biol 2007, 618:229-244.
29. Mason SD, Howlett RA, Kim MJ, Olfert IM, Hogan MC, Mcnulty W, Hickey RP, Wagner PD, Kahn CR, Giordano FJ, Johnson RS. Loss of skeletal muscle HIF-1alpha results in altered exercise endurance. PLoS Biol 2004, 2:e288.
30. Ribom EL, Piehl-Aulin K, Ljunghall S, Ljunggren O, Naessén T. Six months of hormone replacement therapy does not influence muscle strength in postmenopausal women. Maturitas 2002, 42:225-231.
31. Taaffe DR, Luz Villa M, Delay R, Marcus R. Maximal muscle strength of elderly women is not influenced by oestrogen status. Age Ageing 1995, 24:329-333.
32. Ronkainen PH, Kovanen V, Alén M, Pöllänen E, Palonen EM, Ankarberg-Lindgren C, Hämäläinen E, Turpeinen U, Kujala UM, Puolakka J, Kaprio J, Sipilä S. Postmenopausal hormone replacement therapy modifies skeletal muscle composition and function: a study with monozygotic twin pairs. J Appl Physiol 2009, 107:25-33.
33. Shahar E, Redline S, Young T, Boland LL, Baldwin CM, Nieto FJ, O'connor GT, Rapoport DM, Robbins JA. Hormone replacement therapy and sleep-disordered breathing. Am J Respir Crit Care Med 2003, 167:1186-1192.
34. Moran AL, Nelson SA, Landisch RM, Warren GL, Lowe DA. Estradiol replacement reverses ovariectomy-induced muscle contractile and myosin dysfunction in mature female mice. J Appl Physiol 2007, 102:1387-1393.
35. Greising SM, Baltgalvis KA, Lowe DA, Warren GL. Hormone therapy and skeletal muscle strength: a meta-analysis. J Gerontol A Biol Sci Med Sci 2009, 64:1071-1081.
36. Liu YH, Jia SS, Hou YX. Effects of ovariectomy on rat genioglossal muscle contractile properties and fiber-type distribution. Angle Orthod 2009, 79:509-514.
37. Liu YH, Li W, Song WH. Effects of estrogen on sarcoplasmic reticulum Ca2+-ATPase activity and gene expression in genioglossus in chronic intermittent hypoxia rat. Arch Oral Biol 2009, 54:322-328.
38. Dessouroux A, Akwa Y, Baulieu EE. DHEA decreases HIF-1alpha accumulation under hypoxia in human pulmonary artery cells: potential role in the treatment of pulmonary arterial hypertension. J Steroid Biochem Mol Biol 2008, 109:81-89.
39. Mukundan H, Kanagy NL, Resta TC. 17-beta estradiol attenuates hypoxic induction of HIF-1alpha and erythropoietin in Hep3B cells. J Cardiovasc Pharmacol 2004, 44:93-100.
40. Johnson ML, Grazul-Bilska AT, Redmer DA, Reynolds LP. Effects of estradiol-17beta on expression of mRNA for seven angiogenic factors and their receptors in the endometrium of ovariectomized (OVX) ewes. Endocrine 2006, 30:333-342.
41. Liu Y-H, Huang Y, Shao X. Effects of estrogen on genioglossal muscle contractile properties and fiber-type distribution in chronic intermittent hypoxia rats. Eur J Oral Sci 2009, 117:685-690.
42. Dunleavy M, Bradford A, O'halloran KD. Oxidative stress impairs upper airway muscle endurance in an animal model of sleep-disordered breathing. Adv Exp Med Biol 2008, 605:458-462.
43. Tiidus PM. Estrogen and gender effects on muscle damage, inflammation, and oxidative stress. Can J Appl Physiol 2000, 25:274-287.