-
1
-
-
0025867176
-
Permeability of the blood-brain barrier for atenolol studied by positron emission tomography
-
Agon P, Goethals P, van Haver D, Kaufman JM (1991) Permeability of the blood-brain barrier for atenolol studied by positron emission tomography. J Pharm Pharmacol 43(8): 597-600.
-
(1991)
J Pharm Pharmacol
, vol.43
, Issue.8
, pp. 597-600
-
-
Agon, P.1
Goethals, P.2
van Haver, D.3
Kaufman, J.M.4
-
2
-
-
39849088709
-
Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite
-
Ahlborn GJ, Nelson GM, Ward WO, Knapp G, Allen JW, Ouyang M, Roop BC, Chen Y, O'Brien T, Kitchin KT, Delker DA (2008) Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite. Toxicol Appl Pharmacol 227: 400-416.
-
(2008)
Toxicol Appl Pharmacol
, vol.227
, pp. 400-416
-
-
Ahlborn, G.J.1
Nelson, G.M.2
Ward, W.O.3
Knapp, G.4
Allen, J.W.5
Ouyang, M.6
Roop, B.C.7
Chen, Y.8
O'Brien, T.9
Kitchin, K.T.10
Delker, D.A.11
-
3
-
-
0034806293
-
Differential regulation of endogenous glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells
-
Barthel A, Schmoll D, Kruger KD, Bahrenberg G, Walther R, Roth RA, Joost HG (2001) Differential regulation of endogenous glucose-6-phosphatase and phosphoenolpyruvate carboxykinase gene expression by the forkhead transcription factor FKHR in H4IIE-hepatoma cells. Biochem Biophys Res Commun 285: 897-902.
-
(2001)
Biochem Biophys Res Commun
, vol.285
, pp. 897-902
-
-
Barthel, A.1
Schmoll, D.2
Kruger, K.D.3
Bahrenberg, G.4
Walther, R.5
Roth, R.A.6
Joost, H.G.7
-
4
-
-
0027715770
-
Specific targets of covalent drug-protein interactions in hepatocytes and their toxicological significance in drug-induced liver injury
-
Boelsterli UA (1993) Specific targets of covalent drug-protein interactions in hepatocytes and their toxicological significance in drug-induced liver injury. Drug Metab Rev 25: 395-451.
-
(1993)
Drug Metab Rev
, vol.25
, pp. 395-451
-
-
Boelsterli, U.A.1
-
5
-
-
0345701334
-
Aquatic ecotoxicology of luoxetine
-
Brooks BW, Foran CM, Richards SM, Weston JJ, Turner PK, Stanley JK, Solomon KR, Slattery M, LaPoint TW (2003a) Aquatic ecotoxicology of luoxetine. Toxicol Lett 142: 169-183.
-
(2003)
Toxicol Lett
, vol.142
, pp. 169-183
-
-
Brooks, B.W.1
Foran, C.M.2
Richards, S.M.3
Weston, J.J.4
Turner, P.K.5
Stanley, J.K.6
Solomon, K.R.7
Slattery, M.8
Lapoint, T.W.9
-
6
-
-
0012905958
-
Waterborne and sediment toxicity of fluoxetine to select organisms
-
Brooks BW, Turner PK, Stanley JK, Weston JJ, Glidewell EA, Foran CM, Slattery M, LaPoint TW, Huggett DB (2003b) Waterborne and sediment toxicity of fluoxetine to select organisms. Chemosphere 52: 135-142.
-
(2003)
Chemosphere
, vol.52
, pp. 135-142
-
-
Brooks, B.W.1
Turner, P.K.2
Stanley, J.K.3
Weston, J.J.4
Glidewell, E.A.5
Foran, C.M.6
Slattery, M.7
Lapoint, T.W.8
Huggett, D.B.9
-
7
-
-
33947580628
-
Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of hepatic gluconeogenesis in the intact mouse liver
-
Burgess S, He T, Yan Z, Lindner J, Sherry A, Malloy C, Browning J, Magnuson M (2007) Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of hepatic gluconeogenesis in the intact mouse liver. Cell Metabolism 5(4): 313-320.
-
(2007)
Cell Metabolism
, vol.5
, Issue.4
, pp. 313-320
-
-
Burgess, S.1
He, T.2
Yan, Z.3
Lindner, J.4
Sherry, A.5
Malloy, C.6
Browning, J.7
Magnuson, M.8
-
8
-
-
2642711731
-
Occurrence of the pharmaceutical clofibric acid and the herbicide mecoprop in various Swiss Lakes and in the North Sea
-
Buser H-R, Mullere MD, Theobald N (1998) Occurrence of the pharmaceutical clofibric acid and the herbicide mecoprop in various Swiss Lakes and in the North Sea. Environ Sci Technol 32: 188-192.
-
(1998)
Environ Sci Technol
, vol.32
, pp. 188-192
-
-
Buser, H.-R.1
Mullere, M.D.2
Theobald, N.3
-
9
-
-
0032899955
-
Functions of hyaluronan in wound repair
-
Chen WYJ, Abantangelo G (1999) Functions of hyaluronan in wound repair. Wound Repair Regen 7(2): 79-89.
-
(1999)
Wound Repair Regen
, vol.7
, Issue.2
, pp. 79-89
-
-
Chen, W.Y.J.1
Abantangelo, G.2
-
10
-
-
0014057331
-
A kinetic study of drug elimination: The excretion of paracetamol and its metabolites in man
-
Cummings AJ, King ML, Martin BK (1967) A kinetic study of drug elimination: the excretion of paracetamol and its metabolites in man. Br J Pharmacol 29: 150-157.
-
(1967)
Br J Pharmacol
, vol.29
, pp. 150-157
-
-
Cummings, A.J.1
King, M.L.2
Martin, B.K.3
-
12
-
-
26844497714
-
Protein arylation precedes acetaminophen toxicity in a dynamic organ slice culture of mouse kidney
-
Hoivik DJ, Fisher RL, Brendel K, Gandolfi AJ, Khairallahea CSD (1996) Protein arylation precedes acetaminophen toxicity in a dynamic organ slice culture of mouse kidney. Fundam Appl Toxicol 34: 99-104.
-
(1996)
Fundam Appl Toxicol
, vol.34
, pp. 99-104
-
-
Hoivik, D.J.1
Fisher, R.L.2
Brendel, K.3
Gandolfi, A.J.4
Khairallahea, C.S.D.5
-
13
-
-
0015754446
-
Acetaminophen-induced hepatic necrosis: II Role of covalent binding in vivo
-
Jollow DJ, Mitchell JR, Potter WZ, Davis DC, Gillette JR, Brodie BB (1973) Acetaminophen-induced hepatic necrosis: II Role of covalent binding in vivo. J Pharmacol Exp Ther 187: 195-202.
-
(1973)
J Pharmacol Exp Ther
, vol.187
, pp. 195-202
-
-
Jollow, D.J.1
Mitchell, J.R.2
Potter, W.Z.3
Davis, D.C.4
Gillette, J.R.5
Brodie, B.B.6
-
14
-
-
0036081062
-
The KEGG databases at Genome Net
-
Kanehisa M, Goto S, Kawashima S, Nakaya A (2002) The KEGG databases at Genome Net. Nucleic Acids Res 30(1): 42-46.
-
(2002)
Nucleic Acids Res
, vol.30
, Issue.1
, pp. 42-46
-
-
Kanehisa, M.1
Goto, S.2
Kawashima, S.3
Nakaya, A.4
-
15
-
-
38549126643
-
-
Nucleic Acids Res, 36, database issue D480-D484 (doi: 10. 1093/nar/gkm882)
-
Kanehisa M, Araki M, Goto S, Hattori M, Hirakawa M, Itoh M, Katayama T, Kawashima S, Okuda S, Tokimatsu T, Yamanishi Y (2008) KEGG for linking genomes to life and the environment. Nucleic Acids Res, 36, database issue D480-D484 (doi: 10. 1093/nar/gkm882).
-
(2008)
KEGG for Linking Genomes to Life and the Environment
-
-
Kanehisa, M.1
Araki, M.2
Goto, S.3
Hattori, M.4
Hirakawa, M.5
Itoh, M.6
Katayama, T.7
Kawashima, S.8
Okuda, S.9
Tokimatsu, T.10
Yamanishi, Y.11
-
16
-
-
0032766006
-
Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt
-
Kitamura T, Kitamura Y, Kuroda S, Hino Y, Ando M, Kotani K, Konishi H, Matsuzaki H, Kikkawa U, Ogawa W, Kasuga M (1999) Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt. Mol Cell Biol 19: 6286-6296.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6286-6296
-
-
Kitamura, T.1
Kitamura, Y.2
Kuroda, S.3
Hino, Y.4
Ando, M.5
Kotani, K.6
Konishi, H.7
Matsuzaki, H.8
Kikkawa, U.9
Ogawa, W.10
Kasuga, M.11
-
17
-
-
0037085574
-
Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams 1999-2000: A national reconnaissance
-
Kolpin DW, Furlong ET, Meyer MT, Thurman EM, Zaugg SD, Barber LB, Buxton HT (2002) Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams 1999-2000: a national reconnaissance. Environ Sci Technol 36: 1202-1211.
-
(2002)
Environ Sci Technol
, vol.36
, pp. 1202-1211
-
-
Kolpin, D.W.1
Furlong, E.T.2
Meyer, M.T.3
Thurman, E.M.4
Zaugg, S.D.5
Barber, L.B.6
Buxton, H.T.7
-
18
-
-
0034789817
-
Pharmaceuticals in the environment: Emission of pharmaceuticals, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources-a review
-
Kümmerer K (2001) Pharmaceuticals in the environment: emission of pharmaceuticals, diagnostic aids and disinfectants into wastewater by hospitals in relation to other sources-a review. Chemosphere 45: 957-969.
-
(2001)
Chemosphere
, vol.45
, pp. 957-969
-
-
Kümmerer, K.1
-
19
-
-
0025274623
-
Covalent and noncovalent interactions in acute lethal cell injury caused by chemicals
-
Nelson SD, Pearson PG (1990) Covalent and noncovalent interactions in acute lethal cell injury caused by chemicals. Annu Rev Pharmacol Toxicol 30: 169-195.
-
(1990)
Annu Rev Pharmacol Toxicol
, vol.30
, pp. 169-195
-
-
Nelson, S.D.1
Pearson, P.G.2
-
20
-
-
84872791940
-
-
OECD Guideline for Testing of Chemicals 203: Fish, Acute Toxicity Test (Updated Guideline, adopted 17th July 1992) and 204 Fish, Prolonged Toxicity Test: 14-Day Study (Original Guideline, adopted 4th April 1984)
-
OECD Guideline for Testing of Chemicals 203: Fish, Acute Toxicity Test (Updated Guideline, adopted 17th July 1992) and 204 Fish, Prolonged Toxicity Test: 14-Day Study (Original Guideline, adopted 4th April 1984).
-
-
-
-
21
-
-
0031919049
-
Role of binding proteins to IRS-1 in insulin signalling
-
Ogawa W, Matozaki T, Kasuga M (1998) Role of binding proteins to IRS-1 in insulin signalling. Mol Cell Biochem 182: 13-22.
-
(1998)
Mol Cell Biochem
, vol.182
, pp. 13-22
-
-
Ogawa, W.1
Matozaki, T.2
Kasuga, M.3
-
22
-
-
0034947535
-
Multifunctional a-enolase: Its role in diseases
-
Pancholi V (2001) Multifunctional a-enolase: its role in diseases. Cell Mol Life Sci 58: 902-920.
-
(2001)
Cell Mol Life Sci
, vol.58
, pp. 902-920
-
-
Pancholi, V.1
-
23
-
-
0016328928
-
Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters
-
Potter WZ, Thorgeirsson SS, Jollow DJ, Mitchell JR (1974) Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters. Pharmacology 12: 129-143.
-
(1974)
Pharmacology
, vol.12
, pp. 129-143
-
-
Potter, W.Z.1
Thorgeirsson, S.S.2
Jollow, D.J.3
Mitchell, J.R.4
-
24
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414: 799-806.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
25
-
-
1642308567
-
Ranking and prioritization of environmental risks of pharmaceuticals in surface waters
-
Sanderson H, Johnson DJ, Reitsma T, Brain RA, Wilson CJ, Solomon KR (2004) Ranking and prioritization of environmental risks of pharmaceuticals in surface waters. Regulat Toxicol Pharmacol 39: 158-183.
-
(2004)
Regulat Toxicol Pharmacol
, vol.39
, pp. 158-183
-
-
Sanderson, H.1
Johnson, D.J.2
Reitsma, T.3
Brain, R.A.4
Wilson, C.J.5
Solomon, K.R.6
-
26
-
-
24944445127
-
Simultaneous determination of pharmaceutically active compounds in wastewater samples by solid phase extraction and high-performance liquid chromatography with diode array and fluorescence detectors
-
Santos JL, Aparicio I, Alonso E, Callejón M (2005) Simultaneous determination of pharmaceutically active compounds in wastewater samples by solid phase extraction and high-performance liquid chromatography with diode array and fluorescence detectors. Anal Chim Acta 550: 116-122.
-
(2005)
Anal Chim Acta
, vol.550
, pp. 116-122
-
-
Santos, J.L.1
Aparicio, I.2
Alonso, E.3
Callejón, M.4
-
27
-
-
0034680839
-
Regulation of glucose-6-phosphatase gene expression by protein kinase B alpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent effects of insulin on promotor activity
-
Schmoll D, Walker KS, Alessi DR, Grempler R, Burchell A, Guo S, Walther R, Unterman TG (2000) Regulation of glucose-6-phosphatase gene expression by protein kinase B alpha and the forkhead transcription factor FKHR. Evidence for insulin response unit-dependent effects of insulin on promotor activity. J Biol Chem 275: 36324-36333.
-
(2000)
J Biol Chem
, vol.275
, pp. 36324-36333
-
-
Schmoll, D.1
Walker, K.S.2
Alessi, D.R.3
Grempler, R.4
Burchell, A.5
Guo, S.6
Walther, R.7
Unterman, T.G.8
-
28
-
-
44949154341
-
A description of the origins, design and performance of the TRAITS-SGP Atlantic salmon Salmo salar L. cDNA microarray
-
Taggart JB, Bron JE, Martin SAM, Seear PJ, Høyheim B, Talbot R, Carmichael SN, Villeneuve LAN, Sweeney GE, Houlihan DF, Secombes CJ, Tocher DR, Teale AJ (2008) A description of the origins, design and performance of the TRAITS-SGP Atlantic salmon Salmo salar L. cDNA microarray. J Fish Biol 72: 2071-2094.
-
(2008)
J Fish Biol
, vol.72
, pp. 2071-2094
-
-
Taggart, J.B.1
Bron, J.E.2
Martin, S.A.M.3
Seear, P.J.4
Høyheim, B.5
Talbot, R.6
Carmichael, S.N.7
Villeneuve, L.A.N.8
Sweeney, G.E.9
Houlihan, D.F.10
Secombes, C.J.11
Tocher, D.R.12
Teale, A.J.13
-
29
-
-
34247377425
-
GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization
-
Tarze A, Deniaud A, Le Bras M, Maillier E, Molle D, Larochette N, Zamzami N, Jan G, Kroemer G, Brenner C (2007) GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization. Oncogene 26: 2606-2620.
-
(2007)
Oncogene
, vol.26
, pp. 2606-2620
-
-
Tarze, A.1
Deniaud, A.2
Le Bras, M.3
Maillier, E.4
Molle, D.5
Larochette, N.6
Zamzami, N.7
Jan, G.8
Kroemer, G.9
Brenner, C.10
-
30
-
-
0033016287
-
Behavior and occurrence of estrogens in municipal sewage treatment plants-I. investigations in Germany, Canada and Brazil
-
Ternes TA, Stumpf M, Mueller J, Haberer K, Wilken R-D, Servos M (1999) Behavior and occurrence of estrogens in municipal sewage treatment plants-I. investigations in Germany, Canada and Brazil. Sci Total Environ 225: 81-90.
-
(1999)
Sci Total Environ
, vol.225
, pp. 81-90
-
-
Ternes, T.A.1
Stumpf, M.2
Mueller, J.3
Haberer, K.4
Wilken, R.-D.5
Servos, M.6
-
31
-
-
0032210734
-
Occurrence of pharmaceuticals in German sewage treatment plants and rivers
-
Ternes TA (1998) Occurrence of pharmaceuticals in German sewage treatment plants and rivers. Water Res 32: 3245-3260.
-
(1998)
Water Res
, vol.32
, pp. 3245-3260
-
-
Ternes, T.A.1
-
32
-
-
0025966878
-
Hyaluronan and a cell-associated hyaluronan binding protein regulate the locomotion of ras-transformed cells
-
Turley EA, Austen L, Vandeligt K, Clary C (1991) Hyaluronan and a cell-associated hyaluronan binding protein regulate the locomotion of ras-transformed cells. J Cell Biol March 112(5): 1041-1047.
-
(1991)
J Cell Biol March
, vol.112
, Issue.5
, pp. 1041-1047
-
-
Turley, E.A.1
Austen, L.2
Vandeligt, K.3
Clary, C.4
-
33
-
-
0026691008
-
Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention
-
Vermeulen NPE, Bessems JGM, Van De Straat R (1992) Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention. Drug Metab Rev 24: 367-407.
-
(1992)
Drug Metab Rev
, vol.24
, pp. 367-407
-
-
Vermeulen, N.P.E.1
Bessems, J.G.M.2
van de Straat, R.3
-
34
-
-
31444441028
-
3-Phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor and promotes adipocyte differentiation
-
Yin Y, Yuan H, Wang C, Pattabiraman N, Rao M, Pestell RG, Glazer RI (2005) 3-Phosphoinositide-dependent protein kinase-1 activates the peroxisome proliferator-activated receptor and promotes adipocyte differentiation. Mol Endocrinol 20(2): 268-278.
-
(2005)
Mol Endocrinol
, vol.20
, Issue.2
, pp. 268-278
-
-
Yin, Y.1
Yuan, H.2
Wang, C.3
Pattabiraman, N.4
Rao, M.5
Pestell, R.G.6
Glazer, R.I.7
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