Thymus-independent class switch recombination is affected by APRIL

Immunology and Cell Biology

Volumn 86, Issue 6, 2008, Pages 530-534

  Hardenberg, Gijs ^a   Van Bostelen, Liesbeth ^a   Hahne, Michael ^b   Medema, Jan Paul ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

Author keywords

APRIL; Plasma cell; TACI; Thymus independent

Indexed keywords

APRIL PROTEIN; B LYMPHOCYTE ANTIGEN; IMMUNOGLOBULIN A; THYMUS INDEPENDENT ANTIGEN; TRANSMEMBRANE ACTIVATOR AND CAML INTERACTOR; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; MOUSE; NONHUMAN; T LYMPHOCYTE;

ANIMALS; B-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS SWITCHING; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NITROPHENOLS; PHENYLACETATES; THYMUS GLAND; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13;

MUS; MUS MUSCULUS;

EID: 49649112162     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2008.17     Document Type: Article

References (21)

1. Litinskiy MB, Nardelli B, Hilbert DM, He B, Schaffer A, Casali P et al. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat Immunol 2002; 3: 822-829.
2. Castigli E, Wilson SA, Scott S, Dedeoglu F, Xu S, Lam KP et al. TACI and BAFF-R mediate isotype switching in B cells. J Exp Med 2005; 201: 35-39.
3. Castigli E, Scott S, Dedeoglu F, Bryce P, Jabara H, Bhan AK et al. Impaired IgA class switching in APRIL-deficient mice. Proc Natl Acad Sci USA 2004; 101: 3903-3908.
4. Mantchev GT, Cortesão CS, Rebrovich M, Cascalho M, Bram RJ. TACI is required for efficient plasma cell differentiation in response to T-independent type 2 antigens. J Immunol 2007; 179: 2282-2288.
5. Castigli E, Wilson SA, Elkhal A, Ozcan E, Garibyan L, Geha RS. Transmembrane activator and calcium modulator and cyclophilin ligand interactor enhances CD40-driven plasma cell differentiation. J Allergy Clin Immunol 2007; 120: 885-891.
6. Sakurai D, Kanno Y, Hase H, Kojima H, Okumura K, Kobata T. TACI attenuates antibody production costimulated by BAFF-R and CD40. Eur J Immunol 2007; 37: 110-118.
7. Xu S, Lam KP. B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses. Mol Cell Biol 2001; 21: 4067-4074.
8. O'Connor BP, Raman VS, Erickson LD, Cook WJ, Weaver LK, Ahonen C et al. BCMA is essential for the survival of long-lived bone marrow plasma cells. J ExpMed 2004; 199: 91-98.
9. Stein JV, López-Fraga M, Elustondo FA, Carvalho-Pinto CE, Rodríguez D, Gómez-Caro R et al. APRIL modulates B and T cell immunity. J Clin Invest 2002; 109: 1587-1598.
10. Varfolomeev E, Kischkel F, Martin F, Seshasayee D, Wang H, Lawrence D et al. APRIL-deficient mice have normal immune system development. Mol Cell Biol 2004; 24: 997-1006.
11. Macpherson AJ, McCoy K. APRIL in the intestine: a good destination for immunoglobulin A(2). Immunity 2007; 26: 755-757.
12. Hardenberg G, Planelles L, Schwarte CM, van Bostelen L, Le Huong T, Hahne M et al. Specific TLR ligands regulate APRIL secretion by dendritic cells in a PKR-dependent manner. Eur J Immunol 2007; 37: 2900-2911.
13. Planelles L, Carvalho-Pinto CE, Hardenberg G, Smaniotto S, Savino W, Gómez-Caro R et al. APRIL promotes B-1 cell-associated neoplasm. Cancer Cell 2004; 6: 399-408.
14. Hsu MC, Toellner KM, Vinuesa CG, Maclennan IC. B cell clones that sustain long-term plasmablast growth in T-independent extrafollicular antibody responses. Proc Natl Acad Sci USA 2006; 103: 5905-5910.
15. He B, Xu W, Santini PA, Polydorides AD, Chiu A, Estrella J et al. Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL. Immunity 2007; 26: 812-826.
16. Planelles L, Castillo-Gutiérrez S, Medema JP, Morales-Luque A, Merle-Béral H, Hahne M. APRIL but not BLyS serumlevels are increased in chronic lymphocytic leukemia: prognostic relevance of APRIL for survival. Haematologica 2007; 92: 1284-1285.
17. Endo T, Nishio M, Enzler T, Cottam HB, Fukuda T, James DF et al. BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway. Blood 2007; 109: 703-710.
18. Nishio M, Endo T, Tsukada N, Ohata J, Kitada S, Reed JC et al. Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha. Blood 2005; 106: 1012-1020.
19. He B, Chadburn A, Jou E, Schattner EJ, Knowles DM, Cerutti A et al. Lymphoma B cells evade apoptosis through the TNF family members BAFF/BLyS and APRIL. J Immunol 2004; 172: 3268-3279.
20. Chiu A, Xu W, He B, Dillon SR, Gross JA, Sievers E et al. Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL. Blood 2007; 109: 729-739.
21. Abe M, Kido S, Hiasa M, Nakano A, Oda A, Amou H et al. BAFF and APRIL as osteoclast-derived survival factors for myeloma cells: a rationale for TACI-Fc treatment in patients with multiple myeloma. Leukemia 2006; 20: 1313-1315.