Mitochondrial DNA haplogroups modulate the serum levels of biomarkers in patients with osteoarthritis

Annals of the Rheumatic Diseases

Volumn 69, Issue 5, 2010, Pages 910-917

  Rego Perez I ^a   Fernandez Moreno M ^a   Deberg, M ^b   Pertega S ^a   Fenandez Lopez C ^a   Oreiro, N ^a   Henrotin, Y ^b   Blanco, F J ^a  

^a UNIVERSITY OF A CORUÑA   (Spain)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CARTILAGE GLYCOPROTEIN 39; COLLAGEN TYPE 2; COLLAGEN TYPE II TRIPLE HELIX; COLLAGENASE; HYALURONIC ACID; MITOCHONDRIAL DNA; MOLECULAR MARKER; PROCOLLAGEN TYPE 2; UNCLASSIFIED DRUG;

AGED; ARTICLE; CARTILAGE; CELL METABOLISM; CIGARETTE SMOKING; CONTROLLED STUDY; DEMOGRAPHY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HAPLOTYPE; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; SYNOVIAL FLUID;

AGED; BIOLOGICAL MARKERS; COLLAGEN TYPE II; DNA, MITOCHONDRIAL; FEMALE; HAPLOTYPES; HUMANS; HYALURONIC ACID; MALE; MIDDLE AGED; OSTEOARTHRITIS, HIP; OSTEOARTHRITIS, KNEE; PEPTIDE FRAGMENTS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 77951588621     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/ard.2009.117416     Document Type: Article

References (34)

1. Felson DT, Zhang Y. An update on the epidemiology of knee and hip osteoarthritis with a view to prevention. Arthritis Rheum 1998;41:1343-1355 (Pubitemid 28373113)
2. Blackburn WD Jr, Chivers S, Bernreuter W. Cartilage imaging in osteoarthritis. Semin Arthritis Rheum 1996;25:273-281
3. Ravaud P, Giraudeau B, Auleley GR, et al. Variability in knee radiographing: implication for definition of radiological progression in medial knee osteoarthritis. Ann Rheum Dis 1998;57:624-629 (Pubitemid 28513142)
4. Garnero P, Ayral X, Rousseau JC, et al. Uncoupling of type II collagen synthesis and degradation predicts progression of joint damage in patients with knee osteoarthritis. Arthritis Rheum 2002;46:2613-2624 (Pubitemid 36118924)
5. Garnero P, Piperno M, Gineyts E, et al. Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage. Ann Rheum Dis 2001;60:619-626 (Pubitemid 32493990)
6. Christgau S, Garnero P, Fledelius C, et al. Collagen type II C-telopeptide fragments as an index of cartilage degradation. Bone 2001;29:209-215 (Pubitemid 32823562)
7. Rousseau JC, Delmas PD. Biological markers in osteoarthritis. Nat Clin Pract Rheumatol 2007;3:346-356
8. Rousseau JC, Delmas PD. Biological markers in osteoarthritis. Nat Clin Pract Rheumatol 2007;3:346-356
9. Henrotin Y, Addison S, Kraus V, et al. Type II collagen markers in osteoarthritis: what do they indicate? Curr Opin Rheumatol 2007;19:444-450 (Pubitemid 47344236)
10. Terkeltaub R, Johnson K, Murphy A, et al. Invited review: the mitochondrion in osteoarthritis. Mitochondrion 2002;1:301-319
11. Maneiro E, Martín MA, de Andres MC, et al. Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes. Arthritis Rheum 2003;48:700-708 (Pubitemid 36302006)
12. Kim HA, Blanco FJ. Cell death and apoptosis in osteoarthritic cartilage. Curr Drug Targets 2007;8:333-345 (Pubitemid 46299681)
13. Cillero-Pastor B, Caramés B, Lires-Deán M, et al. Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes. Arthritis Rheum 2008;58:2409-2419
14. Blanco FJ, López-Armada MJ, Maneiro E. Role of mitochondria and Osteoarthritis. Mitochondrion 2004;4:715-728
15. Henrotin Y, Kurz B. Antioxidant to treat osteoarthritis: dream or reality? Curr Drug Targets 2007;8:347-357 (Pubitemid 46299682)
16. Grishko VI, Ho R, Wilson GL, et al. Diminished mitochondrial DNA integrity and repair capacity in OA chondrocytes. Osteoarthr Cartil 2009;17:107-113
17. Rego-Pérez I, Fernández-Moreno M, Fernández- López C, et al. Mitochondrial DNA haplogroups: role in the prevalence and severity of knee osteoarthritis. Arthritis Rheum 2008;58:2387-2396
18. Rego I, Fernández-Moreno M, Fernández-López C, et al. Role of European mtDNA haplogroups in the prevalence of hip osteoarthritis in Galicia (Northern Spain). Ann Rheum Dis 2009;2010;69:210-213.
19. Ruiz-Pesini E, Mishmar D, Brandon M, et al. Effects of purifying and adaptive selection on regional variation in human mtDNA. Science 2004;303:223-226 (Pubitemid 38057570)
20. Altman R, Asch E, Bloch D, et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 1986;29:1039-1049
21. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957;16:494-502.
22. Deberg M, Labasse A, Christgau S, et al. New serum biochemical markers (Coll 2-1 and Coll 2-1 NO2) for studying oxidative-related type II collagen network degradation in patients with osteoarthritis and rheumatoid arthritis. Osteoarthr Cartil 2005;13:258-265 (Pubitemid 40277284)
23. Torroni A, Huoponen K, Francalacci P, et al. Classification of European mtDNAs from an analysis of three European populations. Genetics 1996;144:1835-1850 (Pubitemid 26427929)
24. Elliott AL, Kraus VB, Luta G, et al. Serum hyaluronan levels and radiographic knee and hip osteoarthritis in African Americans and Caucasians in the Johnston County Osteoarthritis Project. Arthritis Rheum 2005;52:105-111 (Pubitemid 40129238)
25. Mazières B, Garnero P, Guéguen A, et al. Molecular markers of cartilage breakdown and synovitis at baseline as predictors of structural progression of hip osteoarthritis. The ECHODIAH Cohort. Ann Rheum Dis 2006;65:354-359 (Pubitemid 43268225)
26. Deberg M, Dubuc JE, Labasse A, et al. One-year follow-up of Coll2-1, Coll2-1NO2 and myeloperoxydase serum levels in osteoarthritis patients after hip or knee replacement. Ann Rheum Dis 2008;67:168-174 (Pubitemid 351183304)
27. Sharma L, Dunlop D, Ionescu M. The ratio of collagen breakdown to collagen synthesis and its relationship with the progression of knee osteoarthritis. Arthritis Rheum 2004;50:S282.
28. Manicourt DH, Azria M, Mindeholm L, et al. Oral salmon calcitonin reduces Lequesne's algofunctional index scores and decreases urinary and serum levels of biomarkers of joint metabolism in knee osteoarthritis. Arthritis Rheum 2006;54:3205-3211 (Pubitemid 44622091)
29. Dahmany Y, Marcuello A, Montiel-Sosa FJ, et al. Mitochondrial lineages distribution in the Spanish population: anticipating association studies. An R Acad Nac Farm 2006;72:37-47. (Pubitemid 44077202)
30. Ruiz-Pesini E, Lapeña AC, Díez-Sánchez C, et al. Human mtDNA haplogroups associated with high or reduced spermatozoa motility. Am J Hum Genet 2000;67:682-696 (Pubitemid 30659599)
31. López-Armada MJ, Caramés B, Martín MA, et al. Mitochondrial activity is modulated by TNFalpha and IL-1beta in normal human chondrocyte cells. Osteoarthritis Cartilage 2006;14:1011-1022
32. Maneiro E, López-Armada MJ, de Andres MC, et al. Effect of nitric oxide on mitochondrial respiratory activity of human articular chondrocytes. Ann Rheum Dis 2005;64:388-395 (Pubitemid 40283048)
33. Johansen JS, Hvolris J, Hansen M, et al. Serum YKL-40 levels in healthy children and adults. Comparison with serum and synovial fluid levels of YKL-40 in patients with osteoarthritis or trauma of the knee joint. Br J Rheumatol 1996;35:553-559 (Pubitemid 126719486)
34. Johansen JS, Olee T, Price PA, et al. Regulation of YKL-40 production by human articular chondrocytes. Arthritis Rheum 2001;44:826-837 (Pubitemid 32319775)