Association between HLA-B*1502 and carbamazepine-induced severe cutaneous adverse drug reactions in a Thai population

Epilepsia

Volumn 51, Issue 5, 2010, Pages 926-930

  Tassaneeyakul, Wichittra ^a   Tiamkao, Somsak ^b   Jantararoungtong, Thawinee ^a   Chen, Pei ^c   Lin, Shu Yi ^c   Chen, Wei Hsuan ^c   Konyoung, Parinya ^d   Khunarkornsiri, Usanee ^d   Auvichayapat, Narong ^a   Pavakul, Kasemsin ^e   Kulkantrakorn, Kongkiat ^f   Choonhakarn, Charoen ^b   Phonhiamhan, Siranun ^g   Piyatrakul, Namfon ^h   Aungaree, Thiti ^d   Pongpakdee, Sunsanee ⁱ   Yodnopaglaw, Praphan ^j  

^a KHON KAEN UNIVERSITY   (Thailand)

^b KHON KAEN UNIVERSITY   (Thailand)

^c INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^d Udonthani Hospital   (Thailand)

^e KHON KAEN HOSPITAL   (Thailand)

^f THAMMASAT UNIVERSITY   (Thailand)

^g Nakhon Phanom Hospital   (Thailand)

^h Suanprung Psychiatric Hospital   (Thailand)

ⁱ BHUMIBOL ADULYADEJ HOSPITAL   (Thailand)

^j Surin Hospital   (Thailand)

more..

Author keywords

Carbamazepine; HLA B*1502; Severe cutaneous adverse drug reactions; Stevens Johnson syndrome (SJS); Toxic epidermal necrolysis (TEN)

Indexed keywords

CARBAMAZEPINE; HLA B ANTIGEN;

ADULT; ADVERSE OUTCOME; ALLELE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC SCREENING; HUMAN; MALE; PHARMACOGENETICS; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT; STEVENS JOHNSON SYNDROME; THAILAND; TOXIC EPIDERMAL NECROLYSIS;

ADULT; AGED; ANTICONVULSANTS; ASIAN CONTINENTAL ANCESTRY GROUP; CARBAMAZEPINE; CHILD; EPIDERMAL NECROLYSIS, TOXIC; FEMALE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HLA-B ANTIGENS; HUMANS; MALE; MASS SCREENING; MIDDLE AGED; PHARMACOGENETICS; PREVALENCE; RISK FACTORS; STEVENS-JOHNSON SYNDROME; THAILAND;

EID: 77951572953     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2010.02533.x     Document Type: Article

References (16)

1. Alfirevic A, Mills T, Harrington P, Pinel T, Sherwood J, Jawaid A, Smith JC, March RE, Barratt BJ, Chadwick DW, Kevin Park B, Pirmohamed M. (2006) Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster. Pharmacogenet Genomics 16:287-296.
2. Chung WH, Hung SI, Hong HS, Hsih MS, Yang LC, Ho HC, Wu JY, Chen YT. (2004) Medical genetics: a marker for Stevens-Johnson syndrome. Nature 428:486.
3. Farkas R (2009) Clinical Review, Adverse Events of Carbamazepine. Available from URL:http://www.fda.gov/cder/foi/nda/2007/016608s098, 020712s029,021710-ClinRev.pdf.
4. Ferrell PB, Jr., McLeod HL. (2008) Carbamazepine, HLA-B*1502 and risk of Stevens-Johnson syndrome and toxic epidermal necrolysis: US FDA recommendations. Pharmacogenomics 9:1543-1546.
5. Gerber BO, Pichler WJ. (2006) Noncovalent interactions of drugs with immune receptors may mediate drug-induced hypersensitivity reactions. AAPS J 8:E160-E165.
6. Hung SI, Chung WH, Chen YT. (2005) HLA-B genotyping to detect carbamazepine-induced Stevens-Johnson syndrome: implications for personalizing medicine. Per Med 2:225-237.
7. Hung SI, Chung WH, Jee SH, Chen WC, Chang YT, Lee WR, Hu SL, Wu MT, Chen GS, Wong TW, Hsiao PF, Chen WH, Shih HY, Fang WH, Wei CY, Lou YH, Huang YL, Lin JJ, Chen YT. (2006) Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenet Genomics 16:297-306.
8. Kaniwa N, Saito Y, Aihara M, Matsunaga K, Tohkin M, Kurose K, Sawada J, Furuya H, Takahashi Y, MuramatsuM, Kinoshita S, Abe M, Ikeda H, Kashiwagi M, Song Y, Ueta M, Sotozono C, Ikezawa Z, Hasegawa R. (2008) HLA-B locus in Japanese patients with anti-epileptics and allopurinol-related Stevens-Johnson syndrome and toxic epidermal necrolysis. Pharmacogenomics 9:1617-1622.
9. Lim KS, Kwan P, Tan CT. (2008) Association of HLA-B*1502 allele and carbamazepine induced severe adverse cutaneous drug reaction among Asians, a review. Neurology Asia 13:15-21.
10. Locharernkul C, Loplumlert J, Limotai C, Korkij W, Desudchit T, Tongkobpetch S, Kangwanshiratada O, Hirankarn N, Suphapeetiporn K, Shotelersuk V. (2008) Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with HLA-B*1502 allele in Thai population. Epilepsia 49:2087-2091.
11. Lonjou C, Thomas L, Borot N, Ledger N, de Toma C, LeLouet H, Graf E, Schumacher M, Hovnanian A, Mockenhaupt M, Roujeau JC. (2006) A marker for Stevens-Johnson syndrome...: ethnicity matters. Pharmacogenomics J 6:265-268.
12. Man CB, Kwan P, Baum L, Yu E, Lau KM, Cheng AS, Ng MH. (2007) Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. Epilepsia 48:1015-1018. (Pubitemid 46763406)
13. Pirmohamed M, Lin K, Chadwick D, Park BK. (2001) TNFalpha promoter region gene polymorphisms in carbamazepine-hypersensitive patients. Neurology 56:890-896. (Pubitemid 32290806)
14. Roujeau JC. (2005) Clinical heterogeneity of drug hypersensitivity. Toxicology 209:123-129.
15. Roujeau JC, Kelly JP, Naldi L, Rzany B, Stern RS, Anderson T, Auquier A, Bastuji-Garin S, Correia O, Locati F, Mockenhaupt M, Paoletti C, Shapiro S, Shear N, Schopf E, Kaufman DW. (1995) Medication use and the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis. N Engl J Med 333:1600-1607.
16. Tassaneeyakul W, Jantararoungtong T, Chen P, Lin PY, Tiamkao S, Khunarkornsiri U, Chucherd P, Konyoung P, Vannaprasaht S, Choonhakarn C, Pisuttimarn P, Sangviroon A. (2009) Strong association between HLA-B*5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population. Pharmacogenet Genomics 19:704-709.