Enrichment and isolation of barbigerone from Millettia pachycarpa Benth. using high-speed counter-current chromatography and preparative HPLC

Journal of Separation Science

Volumn 33, Issue 8, 2010, Pages 1010-1017

  Ye, Haoyu ^a   Zhong, Shijie ^a   Li, Yanfang ^b   Tang, Minghai ^a   Peng, Aihua ^a   Hu, Jia ^a   Shi, Jie ^a   He, Shicao ^a   Wu, Wenshuang ^a   Chen, Lijuan ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Anti tumor; Barbigerone; High speed counter current chromatography; Millettia pachycarpa Benth.; Rotenoid derivative

Indexed keywords

ANTI-TUMORS; BARBIGERONE; ETHYL ACETATES; HIGH-SPEED COUNTER CURRENT CHROMATOGRAPHY; METHANOL-WATER; N-HEXANE; N-HEXANE-METHANOL-WATER; NORMAL PHASE; PREPARATIVE HPLC; SEPARATION PROCESS; SOLVENT SYSTEM; TERNARY SOLVENT SYSTEMS;

CHROMATOGRAPHY; ESTERS; HEXANE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHANOL; NUCLEAR MAGNETIC RESONANCE; SPEED; TUMORS;

ORGANIC SOLVENTS;

ACETIC ACID ETHYL ESTER; ANTINEOPLASTIC AGENT; BARBIGERONE; HEXANE; METHANOL; MILLETTIA PACHYCARPA EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COUNTER CURRENT CHROMATOGRAPHY; DRUG ISOLATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PLANT SEED; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SEPARATION TECHNIQUE;

ANTINEOPLASTIC AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERCURRENT DISTRIBUTION; ISOFLAVONES; MAGNETIC RESONANCE SPECTROSCOPY; MILLETTIA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

MILLETTIA;

EID: 77951565370     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900641     Document Type: Article

References (21)

1. Giles, P. M., Pure Appl. Chem. 1999, 71, 587-643.
2. Roseghini, R., Falcao, G. M., Costa, J. F. O., Clarencio, J., Nascimento, I., Velozo, E., Schaer, R., Vale, V., Costa, S. L., Costa, M. D. D., Tardy, M., Meyer, R., Freire, S. M., Planta Med. 2009, 75, 488-493.
3. Park, I., Park, K. K., Park, J. H. Y., Chung, W. Y., Cancer Lett. 2009, 2, 174-181.
4. Chiang, L. C., Ng, L. T., Lin, I. C., Kuo, P. L., Lin, C. C., Cancer Lett. 2006, 2, 207-214.
5. Liu, J. J., Huang, T. S., Cheng, W. F., Lu, F. J., Int. J. Cancer 2003, 4, 559-565.
6. Tham, D. M., Gardner, C. D., Haskell, W. L., J. Clin. Endocrinol. Metab. 1998, 83, 2223-2235.
7. Ingram, D., Sanders, K., Kolybaba, M., Lopez, D., Lancet 1997, 350, 990-994.
8. Constantinou, A. I., Krygier, A. E., Mehta, R. R., Am. J. Clin. Nutr. 1998, 68, 1426-1430.
9. Yu, Z., Li, W., Cancer Lett. 2006, 238, 53-60.
10. Vilain, C., Phytochemistry 1980, 19, 988-989.
11. Yenesew, A., Midiwo, J. O., Waterman, P. G., Phytochemistry 1998, 47, 295-300.
12. Wangensteen, H., Alagmir, M., Rajia, S., Samuelsen, A. B., Malterud, K. E., Planta Med. 2005, 71, 754-758.
13. Wangensteen, H., Miron, A., Alamgir, M., Rajia, S., Samuelsen, A. B., Malterud, K. E., Fitoterapia 2006, 77, 290-295.
14. Yenesew, A., Derese, S., Midiwo, J. O., Phytochemistry 2003, 64, 773-779.
15. Li, Z . G ., Zhao, Y. L., Wu, X., Ye, H. Y., Peng, A., Cao, Z. X., Mao, Y. Q., Zheng, Y. Z., Jiang, P. D., Zhao, X., Chen, L. J., Wei, Y. Q., Cell Physiol. Biochem. 2009, 24, 95-104.
16. Berthod, A. (Ed.), Countercurrent Chromatography, the Support-Free Liquid Stationary Phase, Comprehensive Analytical Chemistry Vol. 38, Elsevier, Amsterdam 2002.
17. Sutherland, I. A., Fisher, D., J. Chromatogr. A 2009, 1216, 740-753.
18. Ye, H. Y., Chen, L. J., Li, Y. F., Peng, A. H., Fu, A. F., Song, H., Tang, M. H., Luo, H. D., Luo, Y. F., Xu, Y. B., Shi, J. Y., Wei, Y. Q., J. Chromatogr. A 2008, 1178, 101-107.
19. Ye, H. Y., Ignatova, S., Peng, A. H., Chen, L. J., Sutherland, I., J. Chromatogr. A 2009, 1216, 5101-5105.
20. Andersen, Q. M., Markham, K . R., (Eds.), Flavonoids: Chemistry, Biochemistry, and Applications, Taylor & Francis, Boca Raton 2006.
21. Fang, N. B., Casida, J. E., J. Org. Chem. 1997, 62, 350-353.