Stereoselective protein binding of tetrahydropalmatine enantiomers in human plasma, HSA, and AGP, but not in rat plasma

Chirality

Volumn 22, Issue 6, 2010, Pages 618-623

  Sun, Dong Li ^a   Huang, Shan Ding ^b   Wu, Pei Sheng ^a   Li, Jia ^a   Ye, Ya Ju ^b   Jiang, Hui Di ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b NINGBO UNIVERSITY   (China)

Author keywords

AGP; Chiral; HSA; Protein binding; Stereoselectivity; Tetrahydropalmatine

Indexed keywords

HUMAN SERUM ALBUMIN; IBUPROFEN; IMIPRAMINE; MIFEPRISTONE; OROSOMUCOID; PLASMA PROTEIN; TETRAHYDROPALMATINE; WARFARIN;

ARTICLE; BINDING COMPETITION; BINDING SITE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENANTIOMER; HUMAN; MALE; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN BINDING; RAT; STEREOCHEMISTRY;

ANIMALS; BERBERINE ALKALOIDS; BINDING, COMPETITIVE; DRUG INTERACTIONS; HUMANS; IBUPROFEN; IMIPRAMINE; MALE; MIFEPRISTONE; OROSOMUCOID; PLASMA; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; SERUM ALBUMIN; STEREOISOMERISM; SUBSTRATE SPECIFICITY; WARFARIN;

EID: 77951555723     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20808     Document Type: Article

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