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Volumn 36, Issue 6, 2010, Pages 1541-1549

Downregulation of 15-lipoxygenase 2 by glucocorticoid receptor in prostate cancer cells

Author keywords

15 lipoxygenase 2; Glucocorticoid receptor; Promoter; Prostate cancer

Indexed keywords

15 LIPOXYGENASE 2; DEXAMETHASONE; DNA FRAGMENT; GLUCOCORTICOID RECEPTOR ALPHA; GLUCOCORTICOID RECEPTOR BETA; LIPOXYGENASE; LUCIFERASE; MIFEPRISTONE; UNCLASSIFIED DRUG;

EID: 77951532119     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000641     Document Type: Article
Times cited : (19)

References (32)
  • 2
    • 0032984374 scopus 로고    scopus 로고
    • 15-Lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma
    • Shappell SB, Boeglin WE, Olson SJ, Kasper S and Brash AR: 15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma. Am J Pathol 155: 235-245, 1999. (Pubitemid 29318721)
    • (1999) American Journal of Pathology , vol.155 , Issue.1 , pp. 235-245
    • Shappell, S.B.1    Boeglin, W.E.2    Olson, S.J.3    Kasper, S.4    Brash, A.R.5
  • 3
    • 0037348168 scopus 로고    scopus 로고
    • Reduced 15S-lipoxygenase-2 expression in esophageal cancer specimens and cells and upregulation in vitro by the cyclooxygenase-2 inhibitor, NS398
    • Xu XC, Shappell SB, Liang Z, et al: Reduced 15S-lipoxygenase-2 expression in esophageal cancer specimens and cells and upregulation in vitro by the cyclooxygenase-2 inhibitor, NS398. Neoplasia 5: 121-127, 2003. (Pubitemid 36369007)
    • (2003) Neoplasia , vol.5 , Issue.2 , pp. 121-127
    • Xu, X.-C.1    Shappell, S.B.2    Liang, Z.3    Song, S.4    Menter, D.5    Subbarayan, V.6    Iyengar, S.7    Tang, D.G.8    Lippman, S.M.9
  • 6
    • 0033798662 scopus 로고    scopus 로고
    • Reduced 15-lipoxygenase-2 immunostaining in prostate adenocarcinoma: Correlation with grade and expression in high-grade prostatic intraepithelial neoplasia
    • Jack GS, Brash AR, Olson SJ, et al: Reduced 15-lipoxygenase-2 immunostaining in prostate adenocarcinoma: correlation with grade and expression in high-grade prostatic intraepithelial neoplasia. Hum Pathol 31: 1146-1154, 2000.
    • (2000) Hum Pathol , vol.31 , pp. 1146-1154
    • Jack, G.S.1    Brash, A.R.2    Olson, S.J.3
  • 8
    • 19944389886 scopus 로고    scopus 로고
    • Cell-autonomous induction of functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) contributes to replicative senescence of human prostate progenitor cells
    • DOI 10.1038/sj.onc.1208406
    • Bhatia B, Tang S, Yang P, et al: Cell-autonomous induction of functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) contributes to replicative senescence of human prostate progenitor cells. Oncogene 24: 3583-3595, 2005. (Pubitemid 40756228)
    • (2005) Oncogene , vol.24 , Issue.22 , pp. 3583-3595
    • Bhatia, B.1    Tang, S.2    Yang, P.3    Doll, A.4    Aumueller, G.5    Newman, R.A.6    Tang, D.G.7
  • 9
    • 4644226778 scopus 로고    scopus 로고
    • Evidence that Sp1 positively and Sp3 negatively regulate and androgen does not directly regulate functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) gene expression in normal human prostate epithelial cells
    • DOI 10.1038/sj.onc.1207913
    • Tang S, Bhatia B, Zhou J, et al: Evidence that Sp1 positively and Sp3 negatively regulate and androgen does not directly regulate functional tumor suppressor 15-lipoxygenase 2 (15-LOX2) gene expression in normal human prostate epithelial cells. Oncogene 23: 6942-6953, 2004. (Pubitemid 39279995)
    • (2004) Oncogene , vol.23 , Issue.41 , pp. 6942-6953
    • Tang, S.1    Bhatia, B.2    Zhou, J.3    Maldonado, C.J.4    Chandra, D.5    Kim, E.6    Fischer, S.M.7    Butler, A.P.8    Friedman, S.L.9    Tang, D.G.10
  • 10
    • 0035336301 scopus 로고    scopus 로고
    • A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: Cloning, physical mapping, and expression
    • DOI 10.1006/geno.2001.6519
    • Krieg P, Marks F and Furstenberger G: A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression. Genomics 73: 323-330, 2001. (Pubitemid 32463728)
    • (2001) Genomics , vol.73 , Issue.3 , pp. 323-330
    • Krieg, P.1    Marks, F.2    Furstenberger, G.3
  • 11
    • 0023906490 scopus 로고
    • Characterization of response elements for androgens, glucocorticoids and progestins in mouse mammary tumour virus
    • Ham J, Thomson A, Needham M, Webb P and Parker M: Characterization of response elements for androgens, glucocorticoids and progestins in mouse mammary tumour virus. Nucleic Acids Res 16: 5263-5276, 1988.
    • (1988) Nucleic Acids Res , vol.16 , pp. 5263-5276
    • Ham, J.1    Thomson, A.2    Needham, M.3    Webb, P.4    Parker, M.5
  • 12
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • Beato M: Gene regulation by steroid hormones. Cell 56: 335-344, 1989.
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 14
    • 0036774934 scopus 로고    scopus 로고
    • Glucocorticoids and treatment of prostate cancer: A preclinical and clinical review
    • DOI 10.1016/S0090-4295(02)01741-7, PII S0090429502017417
    • Fakih M, Johnson CS and Trump DL: Glucocorticoids and treatment of prostate cancer: a preclinical and clinical review. Urology 60: 553-561, 2002. (Pubitemid 35246431)
    • (2002) Urology , vol.60 , Issue.4 , pp. 553-561
    • Fakih, M.1    Johnson, C.S.2    Trump, D.L.3
  • 15
    • 33751217446 scopus 로고    scopus 로고
    • Glucocorticoid up-regulates transforming growth factor-beta (TGF-beta) type II receptor and enhances TGF-beta signaling in human prostate cancer PC-3 cells
    • DOI 10.1210/en.2006-0540
    • Li Z, Chen Y, Cao D, et al: Glucocorticoid up-regulates transforming growth factor-beta (TGF-beta) type II receptor and enhances TGF-beta signaling in human prostate cancer PC-3 cells. Endocrinology 147: 5259-5267, 2006. (Pubitemid 44790581)
    • (2006) Endocrinology , vol.147 , Issue.11 , pp. 5259-5267
    • Li, Z.1    Chen, Y.2    Cao, D.3    Wang, Y.4    Chen, G.5    Zhang, S.6    Lu, J.7
  • 16
    • 33744823251 scopus 로고    scopus 로고
    • Glucocorticoids suppress tumor angiogenesis and in vivo growth of prostate cancer cells
    • DOI 10.1158/1078-0432.CCR-05-2085
    • Yano A, Fujii Y, Iwai A, Kageyama Y and Kihara K: Glucocorticoids suppress tumor angiogenesis and in vivo growth of prostate cancer cells. Clin Cancer Res 12: 3003-3009, 2006. (Pubitemid 43837344)
    • (2006) Clinical Cancer Research , vol.12 , Issue.10 , pp. 3003-3009
    • Yano, A.1    Fujii, Y.2    Iwai, A.3    Kageyama, Y.4    Kihara, K.5
  • 17
    • 45749147849 scopus 로고    scopus 로고
    • Dexamethasone suppresses DU145 cell proliferation and cell cycle through inhibition of the extracellular signal-regulated kinase 1/2 pathway and cyclin D1 expression
    • DOI 10.1111/j.1745-7262.2008.00352.x
    • Gao QZ, Lu JJ, Liu ZD, Zhang H, Wang SM and Xu H: Dexamethasone suppresses DU145 cell proliferation and cell cycle through inhibition of the extracellular signal-regulated kinase 1/2 pathway and cyclin D1 expression. Asian J Androl 10: 635-641, 2008. (Pubitemid 351865769)
    • (2008) Asian Journal of Andrology , vol.10 , Issue.4 , pp. 635-641
    • Gao, Q.-Z.1    Lu, J.-J.2    Liu, Z.-D.3    Zhang, H.4    Wang, S.-M.5    Xu, H.6
  • 18
    • 33947500218 scopus 로고    scopus 로고
    • Tumor suppressor activity of glucocorticoid receptor in the prostate
    • Yemelyanov A, Czwornog J, Chebotaev D, et al: Tumor suppressor activity of glucocorticoid receptor in the prostate. Oncogene 26: 1885-1896, 2007.
    • (2007) Oncogene , vol.26 , pp. 1885-1896
    • Yemelyanov, A.1    Czwornog, J.2    Chebotaev, D.3
  • 20
    • 0242266463 scopus 로고    scopus 로고
    • The dynamic localization of the glucocorticoid receptor in rat C6 glioma cell mitochondria
    • DOI 10.1016/j.mce.2003.07.003
    • Koufali MM, Moutsatsou P, Sekeris CE and Breen KC: The dynamic localization of the glucocorticoid receptor in rat C6 glioma cell mitochondria. Mol Cell Endocrinol 209: 51-60, 2003. (Pubitemid 37353082)
    • (2003) Molecular and Cellular Endocrinology , vol.209 , Issue.1-2 , pp. 51-60
    • Koufali, M.-M.1    Moutsatsou, P.2    Sekeris, C.E.3    Breen, K.C.4
  • 21
    • 44649151676 scopus 로고    scopus 로고
    • Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element
    • Felinski EA, Cox AE, Phillips BE and Antonetti DA: Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element. Exp Eye Res 86: 867-878, 2008.
    • (2008) Exp Eye Res , vol.86 , pp. 867-878
    • Felinski, E.A.1    Cox, A.E.2    Phillips, B.E.3    Antonetti, D.A.4
  • 22
    • 0034986782 scopus 로고    scopus 로고
    • Expression and role of functional glucocorticoid receptors in the human androgen-independent prostate cancer cell line, DU145
    • DOI 10.1677/jme.0.0260185
    • Dondi D, Maggi R, Scaccianoce E, Martini L, Motta M and Poletti A: Expression and role of functional glucocorticoid receptors in the human androgen-independent prostate cancer cell line, DU145. J Mol Endocrinol 26: 185-191, 2001. (Pubitemid 32514609)
    • (2001) Journal of Molecular Endocrinology , vol.26 , Issue.3 , pp. 185-191
    • Dondi, D.1    Maggi, R.2    Scaccianoce, E.3    Martini, L.4    Motta, M.5    Poletti, A.6
  • 23
    • 38549087625 scopus 로고    scopus 로고
    • Dexamethasone-mediated up-regulation of human CYP2A6 involves the glucocorticoid receptor and increased binding of hepatic nuclear factor 4alpha to the proximal promoter
    • DOI 10.1124/mol.107.039354
    • Onica T, Nichols K, Larin M, et al: Dexamethasone-mediated up-regulation of human CYP2A6 involves the glucocorticoid receptor and increased binding of hepatic nuclear factor 4 alpha to the proximal promoter. Mol Pharmacol 73: 451-460, 2008. (Pubitemid 351159215)
    • (2008) Molecular Pharmacology , vol.73 , Issue.2 , pp. 451-460
    • Onica, T.1    Nichols, K.2    Larin, M.3    Ng, L.4    Maslen, A.5    Dvorak, Z.6    Pascussi, J.-M.7    Vilarem, M.-J.8    Maurel, P.9    Kirby, G.M.10
  • 24
    • 0004144140 scopus 로고    scopus 로고
    • 31st edition, UK: Royal Pharmaceutical Society, London
    • Martindale RJ: The extra pharmacopoeia. 31st edition, UK: Royal Pharmaceutical Society, London, 1996.
    • (1996) The Extra Pharmacopoeia.
    • Martindale, R.J.1
  • 26
    • 0029618368 scopus 로고
    • Steroid hormone receptors: Many actors in search of a plot
    • DOI 10.1016/0092-8674(95)90201-5
    • Beato M, Herrlich P and Schutz G: Steroid hormone receptors: many actors in search of a plot. Cell 83: 851-857, 1995. (Pubitemid 26006527)
    • (1995) Cell , vol.83 , Issue.6 , pp. 851-857
    • Beato, M.1    Herrlich, P.2    Schutz, G.3
  • 27
    • 34248342981 scopus 로고    scopus 로고
    • The tumor suppressor effect of the glucocorticoid receptor in skin is mediated via its effect on follicular epithelial stem cells
    • DOI 10.1038/sj.onc.1210108, PII 1210108
    • Chebotaev D, Yemelyanov A, Zhu L, Lavker RM and Budunova I: The tumor suppressor effect of the glucocorticoid receptor in skin is mediated via its effect on follicular epithelial stem cells. Oncogene 26: 3060-3068, 2007. (Pubitemid 46733642)
    • (2007) Oncogene , vol.26 , Issue.21 , pp. 3060-3068
    • Chebotaev, D.1    Yemelyanov, A.2    Zhu, L.3    Lavker, R.M.4    Budunova, I.5
  • 28
    • 0041324898 scopus 로고    scopus 로고
    • The interplay between the glucocorticoid receptor and nuclear factor-κB or activator protein-1: Molecular mechanisms for gene repression
    • DOI 10.1210/er.2002-0006
    • De Bosscher K, Vanden Berghe W and Haegeman G: The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression. Endocr Rev 24: 488-522, 2003. (Pubitemid 37059110)
    • (2003) Endocrine Reviews , vol.24 , Issue.4 , pp. 488-522
    • De Bosscher, K.1    Vanden Berghe, W.2    Haegeman, G.3
  • 29
    • 26944451363 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid receptor action in noninflammatory and inflammatory cells
    • Necela BM and Cidlowski JA: Mechanisms of glucocorticoid receptor action in noninflammatory and inflammatory cells. Proc Am Thorac Soc 1: 239-246, 2004.
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 239-246
    • Necela, B.M.1    Cidlowski, J.A.2
  • 30
    • 0037304336 scopus 로고    scopus 로고
    • Differential expression of the estrogen receptor beta (ERbeta) in human prostate tissue, premalignant changes, and in primary, metastatic, and recurrent prostatic adenocarcinoma
    • DOI 10.1002/pros.10171
    • Fixemer T, Remberger K and Bonkhoff H: Differential expression of the estrogen receptor beta (ERbeta) in human prostate tissue, premalignant changes, and in primary, metastatic, and recurrent prostatic adenocarcinoma. Prostate 54: 79-87, 2003. (Pubitemid 36120323)
    • (2003) Prostate , vol.54 , Issue.2 , pp. 79-87
    • Fixemer, T.1    Remberger, K.2    Bonkhoff, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.