Differential expression of steroid receptors in prostate tissues before and after radiation therapy for prostatic adenocarcinoma

International Journal of Cancer

Volumn 117, Issue 3, 2005, Pages 381-386

  Torlakovic, Emina ^a,b   Lilleby, Wolfgang ^a   Berner, Aasmund ^a   Torlakovic, Goran ^a   Chibbar, Rajni ^b   Furre, Torbjørn ^a   Fosså, Sophie D ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b ROYAL UNIVERSITY HOSPITAL   (Canada)

Author keywords

ER ; Irradiation; Prostate carcinoma

Indexed keywords

ANDROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; PROGESTERONE RECEPTOR; STEROID RECEPTOR;

ARTICLE; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER SURVIVAL; CELL LINE; CONTROLLED STUDY; EVALUATION; GAMMA IRRADIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; NEEDLE BIOPSY; NORWAY; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROSTATE BIOPSY; PROSTATE EPITHELIUM; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RADIATION PROTECTION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE INJURY; TREATMENT OUTCOME; TUMOR BIOPSY;

ADENOCARCINOMA; BIOPSY, NEEDLE; CELL LINE, TUMOR; EPITHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROSTATIC NEOPLASMS; RECEPTORS, STEROID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 26444449536     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.21174     Document Type: Article

References (47)

1. Zlotecki RA. External-beam radiotherapy in the management of carcinoma of the prostate. Cancer Control 2001;8:503-10.
2. Bolla M, Gonzalez D, Warde P, Dubois JB, Mirimanoff RO, Storme G, Bernier J, Kuten A, Sternberg C, Gil T, Collette L, Pierart M. Improved survival in patients with locally advanced prostate cancer treated with radiotherapy and goserelin. N Engl J Med 1997;337:295-300.
3. Eder IE, Culig Z, Putz T, Nessler-Menardi C, Bartsch G, Klocker H. Molecular biology of the androgen receptor: from molecular understanding to the clinic. Eur Urol 2000;40:241-51.
4. Ito T, Tachibana M, Yamamoto S, Nakashima J, Murai M. Expression of estrogen receptor (ER-alpha and ER-beta) mRNA in human prostate cancer. Eur Urol 2001;40:557-63.
5. Lau KM, LaSpina M, Long J, Ho SM. Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation. Cancer Res 2000;60:3175-82.
6. Latil A, Bieche I, Vidaud D, Lidereau R, Berthon P, Cussenot O, Vidaud M. Evaluation of androgen, estrogen (ER alpha and ER beta), and progesterone receptor expression in human prostate cancer by real-time quantitative reverse transcription-polymerase chain reaction assays. Cancer Res 2001;61:1919-26.
7. Lau KM, Leav I, Ho SM. Rat estrogen receptor-alpha and -beta, and progesterone receptor mRNA expression in various prostatic lobes and microdissected normal and dysplastic epithelial tissues of the Noble rats. Endocrinology 1998;139:424-7.
8. Leav I, Lau KM, Adams JY, McNeal JE, Taplin ME, Wang J, Singh H, Ho SM. Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma. Am J Pathol 2001;159:79-92.
9. Srinivasan G, Campbell E, Bashirelahi N. Androgen, estrogen, and progesterone receptors in normal and aging prostates. Microsc Res Tech 1995;30:293-304.
10. Taylor AH, Al-Azzawi F. Immunolocalisation of oestrogen receptor beta in human tissues. J Mol Endocrinol 2000;24:145-55.
11. Culig Z, Hobisch A, Bartsch G, Klocker H. Androgen receptor-an update of mechanisms of action in prostate cancer. Urol Res 2000;28:211-9.
12. Kuiper GG, Enmark E, Pelto-Huikko M, Nilsson S, Gustafsson JA. Cloning of a novel receptor expressed in rat prostate and ovary. Proc Natl Acad Sci USA 1996;93:5925-30.
13. Signoretti S, Loda M. Estrogen receptor β in prostate cancer. Brake pedal or accelerator? Am J Pathol 2001;159:13-6.
14. Royuela M, de Miguel MP Bethencourt, FR, Sánchez-Chapado M, Fraile B, Arenas MI, Paniagua R. Estrogen receptors α and β in the normal, hyperplastic and carcinomatous human prostate. J Endocrinol 2001;168:447-54.
15. Torlakovic E, Lilleby W, Torlakovic G, Fosså SD, Chibbar R. In prostate carcinoma expression of estrogen receptor-beta (ER-β as detected by PPG5/10 antibody has positive association with primary Gleason grade and Gleason score. Hum Pathol 2002;33:646-51.
16. Calvin M. Oestrogens and wound healing. Maturitas 2000;34:195-210.
17. Boden SD, Joyce ME, Oliver B, Heydemann A, Bolander ME. Estrogen receptor mRNA expression in callus during fracture healing in the rat. Calcif Tissue Int 1989;45:324-5.
18. Monaghan BA, Kaplan FS, Lyttle CR, Fallon MD, Boden SD, Haddad JG. Estrogen receptors in fracture healing. Clin Orthop 1992;280:277-80.
19. Ashcroft GS, Dodsworth J, van Boxtel E, Tarnuzzer RW, Horan MA, Schultz GS, Ferguson MW. Estrogen accelerates cutaneous wound healing associated with an increase in TGF-beta1 levels. Nat Med 1997;3:1209-15.
20. Mueller MD, Vigne JL, Minchenko A, Lebovic DI, Leitman DC, Taylor RN. Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors alpha and beta. Proc Natl Acad Sci USA 2000;97:10972-7.
21. Karas RH, van Eickels M, Lydon JP, Roddy S, Kwoun M, Aronovitz M, Baur WE, Conneely O, O'Malley BW, Mendelsohn ME. A complex role for the progesterone receptor in the response to vascular injury. J Clin Invest 2001;108:611-8.
22. Montano MM, Jaiswal AK, Katzenellenbogen BS. Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-alpha and estrogen receptor-beta. J Biol Chem 1998;273:25443-9.
23. Blankenstein MA, Mulder E, Broerse JJ, van der Molen HJ. Oestrogen receptors in rat mammary tissue and plasma concentrations of prolactin during mammary carcinogenesis induced by oestrogen and ionizing radiation. J Endocrinol 1981;88:233-41.
24. Gleason DF. Histological grading and clinical staging of carcinoma of the prostate. In: Tannenbaum M. Urologic pathology: the prostate. Philadelphia: Lea & Febiger, 1977. p 171-97.
25. Vis AN, Kranse R, Nigg AL, van der Kwast TH. Quantitative analysis of the decay of immunoreactivity in stored prostate needle biopsy sections. Am J Clin Pathol 2000;113:369-73.
26. Vujaskovic Z, Anscher MS, Feng QF, Rabbani ZN, Amin K, Samulski TS, Dewhirst MW, Haroon ZA. Radiation-induced hypoxia may perpetuate late normal tissue injury. Int J Radiat Oncol Biol Phys 2001;50:851-5.
27. Li C, Jackson RM. Reactive species mechanisms of cellular hypoxia-reoxygenation injury. Am J Physiol Cell Physiol 2002;282: C227-41.
28. Shim GJ, Wang L, Andersson S, Nagy N, Kis LL, Zhang Q, Makela S, Warner M, Gustafsson JA. Disruption of the estrogen receptor beta gene in mice causes myeloproliferative disease resembling chronic myeloid leukemia with lymphoid blast crisis. Proc Natl Acad Sci USA 2003;100:6694-9.
29. Weihua Z, Makela S, Andersson LC, Salmi S, Saji S, Webster JI, Jensen EV, Nilsson S, Warner M, Gustafsson JA. A role for estrogen receptor beta in the regulation of growth of the ventral prostate. Proc Natl Acad Sci USA 2001;98:6330-5.
30. Weihua Z, Warner M, Gustafsson JA. Estrogen receptor beta in the prostate. Mol Cell Endocrinol 2002;193:1-5.
31. Cheng J, Lee EJ, Madison LD, Lazennec G. Expression of estrogen receptor β in prostate carcinoma cells inhibits invasion and proliferation and triggers apoptosis. FEBS Lett 2004;566:169-72.
32. Kim HT, Kim BC, Kim IY, Mamura M, Seong DH, Jang JJ, Kim SJ. Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis through cleavage of BAD in TSU-PR1 human cancer cells. J Biol Chem 2002;277:32510-5.
33. Lau KM, LaSpina M, Long J, Ho SM. Expression of estrogen receptor (ER)-alpha and ER-beta in normal and malignant prostatic epithelial cells: regulation by methylation and involvement in growth regulation. Cancer Res 2000;60:3175-82.
34. Neubauer BL, McNulty AM, Chedid M, Chen K, Goode RL, Johnson MA, Jones CD, Krishnan V, Lynch R, Osborne HE, Graff JR. The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model. Cancer Res 2003;63:6056-62.
35. Matsuda T, Yamamoto T, Muraguchi A, Saatcioglu F. Cross-talk between transforming growth factor-beta and estrogen receptor signaling through Smad3. J Biol Chem 2001;276:42908-14.
36. Chipuk JE, Cornelius SC, Pultz NJ, Jorgensen JS, Bonham MJ, Kim SJ, Danielpour D. The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3. J Biol Chem 2002;277:1240-8.
37. Hayes SA, Zarnegar M, Sharma M, Yang F, Peehl DM, ten Dijke P, Sun Z. SMAD3 represses androgen receptor-mediated transcription. Cancer Res 2001;61:2112-8.
38. Kang H-Y, Lin H-K, Hu Y-C, Yeh S, Huang K-E, Chang C. From transforming growth factor-β signaling to androgen action: Identification of Smad3 as an androgen receptor coregulator in prostate cancer cells. PNAS 2001;98:3018-23.
39. Schuster N, Krieglstein K. Mechanisms of TGF-beta-mediated apoptosis. Cell Tissue Res 2002;307:1-14.
40. Zhu X, Leav I, Leung YK, Wu M, Liu Q, Gao Y, McNeal JE, Ho SM. Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis. Am J Pathol. 2004;164:2003-12.
41. Li R, Wheeler T, Dai H, Frolov A, Thompson T, Ayala G. High level of androgen receptor is associated with aggressive clinicopathologic features and decreased biochemical recurrence-free survival in prostate: cancer patients treated with radical prostatectomy. Am J Surg Pathol 2004;28:928-34.
42. Øgreid P, Berner A, Dahl O, Rettedal E, Fosså SD. Tissue prostate-specific antigen and androgen receptor immunoreactivity in prostate cancer biopsies before, during and after neo-adjuvant androgen deprivation followed by radiotherapy. Eur Urol 1999;36:116-22.
43. Granfors T, Tomic R, Bergh A, Rydh M, Lofroth PO, Widmark A. After radiotherapy testosterone stimulation is unable to increase growth in the dunning R3327-PAP prostate tumour. Urol Res 1999;27:357-61.
44. Canatan H, Chang WY, Sugimoto Y, Shidaifat F, Kulp SK, Brueggemeier RW, Lin YC. Keratinocyte growth factor (KGF/FGF-7) has a paracrine role in canine prostate: molecular cloning of mRNA encoding canine KGF. DNA Cell Biol 1996;15:247-54.
45. Cooke PS, Buchanan DL, Young P, Setiawan T, Brody J, Korach KS, Taylor J, Lubahn DB, Cunha GR. Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium. Proc Natl Acad Sci USA 1997:94:6535-40.
46. Yi ES, Williams ST, Lee H, Malicki DM, Chin EM, Yin S, Tarpley J, Ulich TR. Keratinocyte growth factor ameliorates radiation- and bleomycin-induced lung injury and mortality. Am J Pathol 1996;149:1963-70.
47. Giuffre R, Palma E, Liccardo G, Sciarra F, Pastore FS, Concolino G. Sex steroid hormones in the pathogenesis of chronic subdural haematoma. Neurochirurgica 1992;35:103-7.