Size, shape, and stamina: The impact of left ventricular geometry on exercise capacity

Hypertension

Volumn 55, Issue 5, 2010, Pages 1143-1149

  Lam, Carolyn S P ^a   Grewal, Jasmine ^a   Borlaug, Barry A ^a   Ommen, Steve R ^a   Kane, Garvan C ^a   McCully, Robert B ^a   Pellikka, Patricia A ^a  

^a MAYO CLINIC   (United States)

Author keywords

Exercise capacity; Hypertension; Hypertrophy; Left ventricle; Remodeling

Indexed keywords

ADULT; AGED; ARTICLE; EXERCISE TOLERANCE; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART RATE; HEART VENTRICLE REMODELING; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; STRESS ECHOCARDIOGRAPHY;

AGED; BLOOD PRESSURE; CARDIOMEGALY; DYSPNEA; ECHOCARDIOGRAPHY; ECHOCARDIOGRAPHY, TRANSESOPHAGEAL; EXERCISE TEST; FATIGUE; FEMALE; HEART RATE; HEART VENTRICLES; HUMANS; MALE; MIDDLE AGED; ORGAN SIZE; PATIENT SELECTION; STROKE VOLUME; VENTRICULAR REMODELING;

EID: 77951498773     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.109.146845     Document Type: Article

References (41)

1. Najjar SS, Schulman SP, Gerstenblith G, Fleg JL, Kass DA, O'Connor F, Becker LC, Lakatta EG. Age and gender affect ventricular-vascular coupling during aerobic exercise. J Am Coll Cardiol. 2004;44:611-617. (Pubitemid 39078188)
2. Grewal J, McCully RB, Kane GC, Lam C, Pellikka PA. Left ventricular function and exercise capacity. JAMA. 2009;301:286-294.
3. Park S, Ha JW, Shim CY, Choi EY, Kim JM, Ahn JA, Lee SW, Rim SJ, Chung N. Gender-related difference in arterial elastance during exercise in patients with hypertension. Hypertension. 2008;51:1163-1169. (Pubitemid 351398976)
4. Chantler PD, Melenovsky V, Schulman SP, Gerstenblith G, Becker LC, Ferrucci L, Fleg JL, Lakatta EG, Najjar SS. The sex-specific impact of systolic hypertension and systolic blood pressure on arterial-ventricular coupling at rest and during exercise. Am J Physiol Heart Circ Physiol. 2008;295:H145-H153.
5. Borlaug BA, Melenovsky V, Russell SD, Kessler K, Pacak K, Becker LC, Kass DA. Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction. Circulation. 2006;114:2138-2147. (Pubitemid 44747894)
6. Tomiyama H, Doba N, Kushiro T, Yamashita M, Kanmatsuse K, Kajiwara N, Yoshida H, Hinohara S. Prospective studies on left ventricular geometric patterns and exercise tolerance in unmedicated men with borderline and mild hypertension. J Hypertens. 1996;14:1223-1228. (Pubitemid 26343502)
7. Pierson LM, Bacon SL, Sherwood A, Hinderliter AL, Babyak M, Gullette EC, Waugh R, Blumenthal JA. Association between exercise capacity and left ventricular geometry in overweight patients with mild systemic hypertension. Am J Cardiol. 2004;94:1322-1325. (Pubitemid 39469962)
8. Ganau A, Devereux RB, Roman MJ, de Simone G, Pickering TG, Saba PS, Vargiu P, Simongini I, Laragh JH. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension. J Am Coll Cardiol. 1992;19:1550-1558.
9. Cohn JN, Ferrari R, Sharpe N. Cardiac remodeling-concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling-behalf of an International Forum on Cardiac Remodeling. J Am Coll Cardiol. 2000;35:569-582.
10. Lang RM, Bierig M, Devereux RB, Flachskampf FA, Foster E, Pellikka PA, Picard MH, Roman MJ, Seward J, Shanewise JS, Solomon SD, Spencer KT, Sutton MS, Stewart WJ. Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr. 2005;18:1440-1463. (Pubitemid 41821197)
11. Devereux RB, Wachtell K, Gerdts E, Boman K, Nieminen MS, Papa-demetriou V, Rokkedal J, Harris K, Aurup P, Dahlof B. Prognostic significance of left ventricular mass change during treatment of hypertension. JAMA. 2004;292:2350-2356. (Pubitemid 39491919)
12. Wachtell K, Dahlof B, Rokkedal J, Papademetriou V, Nieminen MS, Smith G, Gerdts E, Boman K, Bella JN, Devereux RB. Change of left ventricular geometric pattern after 1 year of antihypertensive treatment: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) Study. Am Heart J. 2002;144:1057-1064. (Pubitemid 36026920)
13. Devereux RB, Dahlof B, Gerdts E, Boman K, Nieminen MS, Papadem-etriou V, Rokkedal J, Harris KE, Edelman JM, Wachtell K. Regression of hypertensive left ventricular hypertrophy by losartan compared with atenolol: the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) Trial. Circulation. 2004;110:1456-1462. (Pubitemid 39238023)
14. Hill J, Timmis A. Exercise tolerance testing. BMJ. 2002;324:1084-1087.
15. Pellikka PA, Nagueh SF, Elhendy AA, Kuehl CA, Sawada SG. American Society of Echocardiography recommendations for performance, interpretation, and application of stress echocardiography. J Am Soc Echocardiogr. 2007;20:1021-1041. (Pubitemid 47321932)
16. Quinones MA, Waggoner AD, Reduto LA, Nelson JG, Young JB, Winters WL Jr, Ribeiro LG, Miller RR. A new, simplified and accurate method for determining ejection fraction with two-dimensional echocar-diography. Circulation. 1981;64:744-753.
17. Stamm RB, Carabello BA, Mayers DL, Martin RP. Two-dimensional echocardiographic measurement of left ventricular ejection fraction: prospective analysis of what constitutes an adequate determination. Am Heart J. 1982;104:136-144.
18. Arruda AM, McCully RB, Oh JK, Mahoney DW, Seward JB, Pellikka PA. Prognostic value of exercise echocardiography in patients after coronary artery bypass surgery. Am J Cardiol. 2001;87:1069-1073. (Pubitemid 32710321)
19. Grossman W, Jones D, McLaurin LP. Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest. 1975;56:56-64.
20. Gaasch WH. Left ventricular radius to wall thickness ratio. Am J Cardiol. 1979;43:1189-1194. (Pubitemid 9191003)
21. Devereux RB, James GD, Pickering TG. What is normal blood pressure? Comparison of ambulatory pressure level and variability in patients with normal or abnormal left ventricular geometry. Am J Hypertens. 1993;6: 211S-215S.
22. Koren MJ, Devereux RB, Casale PN, Savage DD, Laragh JH. Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med. 1991;114:345-352.
23. Levy D, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med. 1990;322:1561-1566. (Pubitemid 20176696)
24. Sano M, Schneider MD. Still stressed out but doing fine: normalization of wall stress is superfluous to maintaining cardiac function in chronic pressure overload. Circulation. 2002;105:8-10. (Pubitemid 34049134)
25. Perrino C, Naga Prasad SV, Mao L, Noma T, Yan Z, Kim HS, Smithies O, Rockman HA. Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. J Clin Invest. 2006;116:1547-1560. (Pubitemid 43911009)
26. Opie LH, Commerford PJ, Gersh BJ, Pfeffer MA. Controversies in ventricular remodelling. Lancet. 2006;367:356-367.
27. Gharavi AG, Diamond JA, Goldman AY, Coplan NL, Jhang JS, Steinmetz M, Goldsmith R, Phillips RA. Resting diastolic function and left ventricular mass are related to exercise capacity in hypertensive men but not in women. Am J Hypertens. 1998;11:1252-1257. (Pubitemid 28494190)
28. Khattar RS, Acharya DU, Kinsey C, Senior R, Lahiri A. Longitudinal association of ambulatory pulse pressure with left ventricular mass and vascular hypertrophy in essential hypertension. J Hypertens. 1997;15: 737-743. (Pubitemid 27249989)
29. Lam CS, Roger VL, Rodeheffer RJ, Bursi F, Borlaug BA, Ommen SR, Kass DA, Redfield MM. Cardiac structure and ventricular-vascular function in persons with heart failure and preserved ejection fraction from Olmsted County, Minnesota. Circulation. 2007;115:1982-1990.
30. Melenovsky V, Borlaug BA, Rosen B, Hay I, Ferruci L, Morell CH, Lakatta EG, Najjar SS, Kass DA. Cardiovascular features of heart failure with preserved ejection fraction versus nonfailing hypertensive left ventricular hypertrophy in the urban Baltimore community: the role of atrial remodeling/dysfunction. J Am Coll Cardiol. 2007;49:198-207. (Pubitemid 46070209)
31. Ennezat PV, Lefetz Y, Marechaux S, Six-Carpentier M, Deklunder G, Montaigne D, Bauchart JJ, Mounier-Vehier C, Jude B, Neviere R, Bauters C, Asseman P, de Groote P, Lejemtel TH. Left ventricular abnormal response during dynamic exercise in patients with heart failure and preserved left ventricular ejection fraction at rest. J Card Fail. 2008;14: 475-480.
32. Brubaker PH, Joo KC, Stewart KP, Fray B, Moore B, Kitzman DW. Chronotropic incompetence and its contribution to exercise intolerance in older heart failure patients. J Cardiopulm Rehabil. 2006;26:86-89. (Pubitemid 44474302)
33. Borlaug BA, Lam CS, Olson TP, Flood KS, Johnson BD, Redfield MM. Cardiovascular reserve function in heart failure with preserved ejection fraction: systolic versus diastolic determinants. Circulation. 2008;118: S1022.
34. Aurigemma GP, Silver KH, Priest MA, Gaasch WH. Geometric changes allow normal ejection fraction despite depressed myocardial shortening in hypertensive left ventricular hypertrophy. J Am Coll Cardiol. 1995;26: 195-202.
35. Devereux RB, de Simone G, Roman MJ. From 'compensated' left ventricular hypertrophy to heart failure: is the transition so dramatic? Heart Fail. 1994;10:102-108.
36. Kolwicz SC, MacDonnell SM, Renna BF, Reger PO, Seqqat R, Rafiq K, Kendrick ZV, Houser SR, Sabri A, Libonati JR. Left ventricular remodeling with exercise in hypertension. Am J Physiol Heart Circ Physiol. 2009;297:H1361-H1368.
37. Miyachi M, Yazawa H, Furukawa M, Tsuboi K, Ohtake M, Nishizawa T, Hashimoto K, Yokoi T, Kojima T, Murate T, Yokota M, Murohara T, Koike Y, Nagata K. Exercise training alters left ventricular geometry and attenuates heart failure in dahl salt-sensitive hypertensive rats. Hypertension. 2009;53: 701-707.
38. Morris CK, Myers J, Froelicher VF, Kawaguchi T, Ueshima K, Hideg A. Nomogram based on metabolic equivalents and age for assessing aerobic exercise capacity in men. J Am Coll Cardiol. 1993;22:175-182. (Pubitemid 23189950)
39. Myers J, Prakash M, Froelicher V, Do D, Partington S, Atwood JE. Exercise capacity and mortality among men referred for exercise testing. N Engl J Med. 2002;346:793-801. (Pubitemid 34987553)
40. Balady GJ, Larson MG, Vasan RS, Leip EP, O'Donnell CJ, Levy D. Usefulness of exercise testing in the prediction of coronary disease risk among asymptomatic persons as a function of the Framingham risk score. Circulation. 2004;110:1920-1925. (Pubitemid 39331902)
41. Kokkinos P, Myers J, Kokkinos JP, Pittaras A, Narayan P, Manolis A, Karasik P, Greenberg M, Papademetriou V, Singh S. Exercise capacity and mortality in black and white men. Circulation. 2008;117:614-622.