Chitosan derivative nanocarrier: Safety evaluation, antibacterial property and ascorbyl palmitate encapsulation

Journal of Microencapsulation

Volumn 27, Issue 3, 2010, Pages 218-225

  Wittayasuporn, Mayura ^a   Rengpipat, Sirirat ^a   Palaga, Tanapat ^a   Asawanonda, Pravit ^a   Anumansirikul, Nattaporn ^a   Wanichwecharungruang, Supasorn P ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Ascorbyl palmitate; Chitosan; Cytotoxicity; Irritation; Photostability

Indexed keywords

ASCORBYL PALMITATE; CHITOSAN DERIVATIVE; NANOCAPSULE; NANOCARRIER; POLY(ETHYLENE OXIDE) 4 METHOXYCINNAMOYLPHTHALOYLCHITOSAN DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; ANTIBACTERIAL ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SAFETY; DRUG STABILITY; ESCHERICHIA COLI; FEMALE; HUMAN; HUMAN CELL; MALE; MELANOMA CELL; NANOENCAPSULATION; NORMAL HUMAN; PATCH TEST; PHOTOPATCH TEST; PROTON NUCLEAR MAGNETIC RESONANCE; SINGLE DRUG DOSE; SKIN IRRITATION; STAPHYLOCOCCUS AUREUS; TOXICITY TESTING;

ADULT; ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; ASCORBIC ACID; CELL LINE, TUMOR; CELL SURVIVAL; CHITOSAN; DRUG CARRIERS; ESCHERICHIA COLI; FEMALE; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; NANOPARTICLES; SKIN IRRITANCY TESTS; STAPHYLOCOCCUS AUREUS; YOUNG ADULT;

EID: 77951490873     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652040903067836     Document Type: Article

References (20)

1. Anumansirikul N, Wittayasuporn M, Klinubol P, Tachaprutinun A, Wanichwecharungruang SP. 2008. UV-screening chitosan nanocontainers: Increasing the photostability of encapsulated materials and controlled release. Nanotechnology 19:205101 (9pp).
2. Chung Y-C, Chen C-Y. 2008. Antibacterial characteristics and activity of acid-soluble chitosan. Bioresource Technol 99:2806-2814.
3. Chung YC, Su YP, Chen CC, Jia G, Wang HL, Wu JCG. 2004. Relationship between antibacterial activity of chitosan and surface characteristics of cell wall. Acta Pharmacol Sin 25:932-936.
4. Chung YC, Wang HL, Chen YM, Li SL. 2003. Effect of abiotic factors on the antibacterial activity of chitosan against waterborne pathogens. Bioresource Technol 88:179-184.
5. Diaz C, Vargas E, Gätjens-Boniche O. 2006. Cytotoxic effect induced by retinoic acid loaded into galactosyl-sphingosine containing liposomes on human hepatoma cell lines. Int J Pharm 325:108-115.
6. Harish Prashanth KV, Tharanathan RN. 2007. Chitin/chitosan: Modifications and their unlimited application potential-an overview. Trends Food Sci Tech 18:117-131.
7. Hjerde RJN, Vårum KM, Grasdalen H, Tokura S, Smidsrød O. 1997. Chemical composition of O-(carboxymethyl)-chitins in relation to lysozyme degradation rates. Carbohyd Polym 34:131-139.
8. Illum L, Jabbal-Gill I, Hinchcliffe M, Fisher AN, Davis SS. 2001. Chitosan as a novel nasal delivery system for vaccines. Adv Drug Del Rev 51:81-96.
9. Jang K-I, Lee HG. 2008. Stability of chitosan nanoparticles for l-ascorbic acid during heat treatment in aqueous solution. J Agric Food Chem 56:1936-1941.
10. Jiang X, Dai H, Leong KW, Goh SH, Mao HQ, Yang YY. 2006. Chitosan-g-PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions. J Gene Med 8:477-487.
11. Kim IY, Seo SJ, Moon HS, Yoo MK, Park IY, Kim BC. 2008. Chitosan and its derivatives for tissue engineering applications. Biotechnol Adv 26:1-21.
12. Kristl J, Volk B, Gasperlin M, Sentjurc M, Jurkovic P. 2003. Effect of colloidal carriers on ascorbyl palmitate stability. Eur J Pharm Sci 19:181-189.
13. Liu WG, Zhang JR, Cao ZQ, Xu FY, Yao KD. 2004. A chitosan-arginine conjugate as a novel anticoagulation biomaterial. J Mater Sci Mater Med 15:1199-1203.
14. Ohya Y, Cai R, Nishizawa H, Hara K, Ouchi T. 2000. Preparation of PEGgrafted chitosan nanoparticles as peptide drug carriers. STP Pharma Sci 10:77-82.
15. Qi L, Xu Z, Jiang X, Hu C, Zou X. 2004. Preparation and antibacterial activity of chitosan nanoparticles. Carbohyd Res 339: 2693-2700.
16. Qin C, Gao J, Wang L, Zeng L, Liu Y. 2006. Safety evaluation of short-term exposure to chitooligomers from enzymic preparation. Food Chem Toxicol 44:855-861.
17. Ravi Kumar MNV, Bakowsky U, Lehr CM. 2004. Preparation and characterization of cationic PLGA nanospheres as DNA carriers. Biomaterials 25:1771-1777.
18. Shi C, Zhu Y, Ran X, Wang M, Su Y, Cheng T. 2006. Therapeutic potential of chitosan and its derivatives in regenerative medicine. J Surg Res 133:185-192.
19. Üner M, Wissing SA, Yener G, Muller RH. 2005. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for application of ascorbyl palmitate. Pharmazie 60:577-582.
20. Vårum KM, Myhr MM, Hjerde RJN, Smidsrød O. 1997. In vitro degradation rates of partially N-acetylated chitosans in human serum. Carbohyd Res 299:99-101.