Hepatitis C virus core protein interacts with fibrinogen-β and attenuates cytokine stimulated acute-phase response

Hepatology

Volumn 51, Issue 5, 2010, Pages 1505-1513

  Ait Goughoulte, Malika ^a   Banerjee, Arup ^a   Meyer, Keith ^a   Mazumdar, Budhaditya ^a   Saito, Kousuke ^a   Ray, Ratna B ^a   Ray, Ranjit ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; COMPLEMENTARY DNA; FIBRINOGEN BETA; GENOMIC RNA; INTERLEUKIN 6; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE PHASE RESPONSE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA LIBRARY; FEEDBACK SYSTEM; GENETIC TRANSFECTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INNATE IMMUNITY; LIVER CELL; LIVER CELL CULTURE; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PERSISTENT INFECTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM;

ACUTE-PHASE REACTION; CELL LINE; FIBRINOGEN; HEPACIVIRUS; HEPATOCYTES; HUMANS; INTERLEUKIN-6; PROTEIN INTERACTION MAPPING; PROTEIN SUBUNITS; TUMOR NECROSIS FACTOR-ALPHA; TWO-HYBRID SYSTEM TECHNIQUES; VIRAL CORE PROTEINS;

EID: 77951470464     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.23502     Document Type: Article

References (30)

1. Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 1999;340:448-454. (Pubitemid 29084777)
2. Choy EH, Panayi GS. Cytokine pathways and joint inflammation in rheumatoid arthritis. N Engl J Med 2001;344:907-916. (Pubitemid 32224400)
3. Baumann H, Gauldie J. The acute phase response. Immunol Today 1994;15:74-80.
4. Black PH. The inflammatory response is an integral part of the stress response: implications for atherosclerosis, insulin resistance, type II diabetes and metabolic syndrome X. Brain Behav Immun 2003;17:350-364.
5. Gauldie J, Richards C, Harnish D, Lansdorp P, Baumann H. Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc Natl Acad Sci U S A 1987;84:7251-7255.
6. Castell JV, Gomez-Lechon MJ, David M, Andus T, Geiger T, Trullenque R, et al. Interleukin-6 is the major regulator of acute phase protein synthesis in adult human hepatocytes. FEBS Lett 1989;242:237-239. (Pubitemid 19020112)
7. Otto JM, Grenett H, Fuller GM. The coordinated regulation of fibrinogen gene transcription by hepatocyte-stimulating factor and dexamethasone. J Cell Biol 1987;105:1067-1072. (Pubitemid 18029832)
8. Simpson-Haidaris PJ. Induction of fibrinogen biosynthesis and secretion from cultured pulmonary epithelial cells. Blood 1997;89:873-882. (Pubitemid 27121280)
9. Zhang Z, Fuller GM. Interleukin-1β inhibits interleukin 6-mediated rat γ fibrinogen gene expression. Blood 2000;96:3466-3472.
10. Westra J, Bijzet J, Doornbos-van der Meer B, van Rijswijk MH, Limburg PC. Differential influence of p38 mitogen activated protein kinase (MAPK) inhibition on acute phase protein synthesis in human hepatoma cell lines. Ann Rheum Dis 2006;65:929-935.
11. Bode JG, Fischer R, Haussinger D, Graeve L, Heinrich PC, Schaper F. The inhibitory effect of IL-1β on IL-6-induced 2-macroglobulin expression is due to activation of NF-κB. J Immunol 2001;167:1469-1481. (Pubitemid 32703146)
12. Zhang Z, Jones S, Hagood JS, Fuentes NL, Fuller GM. STAT3 acts as a co-activator of glucocorticoid receptor signaling. J Biol Chem 1997;272:30607-30610. (Pubitemid 27527489)
13. Shrivastava A, Manna SK, Ray R, Aggarwal BB. Ectopic expression of hepatitis C virus core protein differentially regulates nuclear transcription factors. J Virol 1998;72:9722972-9722978
14. Basu A, Meyer K, Lai KK, Saito K, Di Bisceglie AM, Grosso LE, et al. Microarray analyses and molecular profiling of Stat3 signaling pathway induced by hepatitis C virus core protein in human hepatocytes. Virology 2009;49:347-358. (Pubitemid 43782881)
15. Wang Y, Ripperger J, Fey GH, Samols D, Kordula T, Wetzler M, et al. Modulation of hepatic acute phase gene expression by epidermal growth factor and src protein tyrosine kinases in murine and human hepatic cells. HEPATOLOGY 1999;30:682-697. (Pubitemid 29409413)
16. Hosui A, Ohkawa K, Ishida H, Sato A, Nakanishi F, Ueda K, et al. Hepatitis C virus core protein differently regulates the JAK-STAT signaling pathway under interleukin-6 and interferon-gamma stimuli. J Biol Chem 2003;278:28562-28571. (Pubitemid 36935761)
17. Remy I, Michnick SW. A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways. Methods (Duluth) 2004;32:381-388. (Pubitemid 38299329)
18. Remy I, Michnick SW. Mapping biochemical networks with protein-fragment complementation assays. Methods Mol Biol 2004;261:411-426.
19. Banerjee A, Saito K, Meyer K, Banerjee S, Ait-Goughoulte M, Ray RB, et al. Hepatitis C virus core protein and cellular protein HAX-1 promotes 5-fluorouracil mediated hepatocyte growth inhibition. J Virol 2009;83:9663-9671.
20. Verschuur M, de Jong M, Felida L, de Maat MPM, Vos HL. A hepatocyte nuclear factor-3 site in the fibrinogen promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent-148C/T polymorphism. J Biol Chem 2005;280:16763-16771. (Pubitemid 41389134)
21. Majumder M, Ghosh AK, Steele R, Ray R, Ray RB. Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner. J Virol 2001;75:401-407. (Pubitemid 32094698)
22. Koj A. Initiation of acute phase response and synthesis of cytokines. Biochim Biophys Acta 1996;1317:84-94. (Pubitemid 26388776)
23. Margarit I, Bonacci S, Pietrocola G, Rindi S, Ghezzo C, Bombaci M, et al. Capturing host-pathogen interactions by protein microarrays: identification of novel streptococcal proteins binding to human fibronectin, fibrinogen, and C4BP. FASEB J 2009;23:3100-3112.
24. Carlsson F, Sandin C, Lindahl G. 2005. Human fibrinogen bound to Streptococcus pyogenes M protein inhibits complement deposition via the classical pathway. Mol Microbiol 2005;56:28-39. (Pubitemid 40461485)
25. Lee LYL, Liang X, Höök M, Brown EL. Identification and characterization of the C3 binding domain of the Staphylococcus aureus extracellular fibrinogen-binding protein (Efb). J Biol Chem 2004;279:50710- 50716. (Pubitemid 40017808)
26. Daoud MS, el-Azhary RA, Gibson LE, Lutz ME, Daoud S. Chronic hepatitis C, cryoglobulinemia, and cutaneous necrotizing vasculitis. Clinical, pathologic, and immunopathologic study of twelve patients. J Am Acad Dermatol 1996;34:219-223.
27. Dumestre-Perard C, Ponard D, Drouet C, Leroy V, Zarski JP, Dutertre N, et al. Complement C4 monitoring in the follow-up of chronic hepatitis C treatment. Clin Exp Immunol 2002;127:131-136. (Pubitemid 34155468)
28. Nascimento MM, Bruchfeld A, Suliman ME, Hayashi SY, Pecoits-Filho R, Manfro RC, et al. Effect of hepatitis C serology on C-reactive protein in a cohort of Brazilian hemodialysis patients. Braz J Med Biol Res 2005;38:783-788. (Pubitemid 40867519)
29. Van Lenten BJ, Wagner AC, Nayak DP, Hama S, Navab M, Fogelman AM. High-density lipoprotein loses its anti-inflammatory properties during acute influenza A infection. Circulation 2001;103:2283-2288. (Pubitemid 32433719)
30. Siagris D, Christofidou M, Theocharis GJ, Pagoni N, Papadimitriou C, Lekkou A, et al. Serum lipid pattern in chronic hepatitis C: histological and virological correlations. J Viral Hepat 2006;13:56-61.