Health economic burden of patients with restless legs syndrome in a German ambulatory setting

PharmacoEconomics

Volumn 28, Issue 5, 2010, Pages 381-393

  Dodel, Richard ^a   Happe, Svenja ^b,c   Peglau, Ines ^d   Mayer, Geert ^e   Wasem, Jürgen ^f   Reese, Jens Peter ^a   Giani, Guido ^g   Geraedts, Max ^h   Trenkwalder, Claudia ⁱ   Oertel, Wolfgang H ^a   Stiasny Kolster, Karin ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c KLINIKUM BREMEN OST   (Germany)

^d Private Practice   (Germany)

^e Hephata Klinik   (Germany)

^f UNIVERSITY OF DUISBURG ESSEN   (Germany)

^g HEINRICH HEINE UNIVERSITY   (Germany)

^h UNIVERSITY OF WITTEN HERDECKE   (Germany)

ⁱ Paracelsus Elena Klinik   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; AMBULATORY CARE; ARTICLE; BECK DEPRESSION INVENTORY; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; DRUG COST; EPWORTH SLEEPINESS SCALE; FEMALE; GERMANY; HEALTH CARE COST; HEALTH CARE PLANNING; HEALTH CARE SYSTEM; HEALTH ECONOMICS; HEALTH INSURANCE; HEALTH STATUS; HOSPITALIZATION COST; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT ASSESSMENT; PATIENT CARE; PRIORITY JOURNAL; QUALITY OF LIFE; QUESTIONNAIRE; RESTLESS LEGS SYNDROME; SOCIOECONOMICS; TREATMENT DURATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMBULATORY CARE; AMBULATORY CARE FACILITIES; COST OF ILLNESS; COSTS AND COST ANALYSIS; DRUG COSTS; EQUIPMENT AND SUPPLIES; FEMALE; GERMANY; HEALTH CARE COSTS; HOSPITALIZATION; HUMANS; INPATIENTS; MALE; MIDDLE AGED; PHYSICAL THERAPY MODALITIES; QUALITY OF LIFE; QUESTIONNAIRES; RESTLESS LEGS SYNDROME; YOUNG ADULT;

EID: 77951459580     PISSN: 11707690     EISSN: 11792027     Source Type: Journal    
DOI: 10.2165/11531030-000000000-00000     Document Type: Article

References (45)

1. Garcia-Borreguero D, Egatz R, Winkelmann J, et al. Epidemiology of restless legs syndrome: the current status. Sleep Med Rev 2006; 10 (3): 153-167 (Pubitemid 43817594)
2. Allen RP, Picchietti D, Hening WA, et al. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the Restless Legs Syndrome Diagnosis and Epidemiology Workshop at the National Institutes of Health. Sleep Med 2003; 4 (2): 101-119
3. Hening W, Walters AS, Allen RP, et al. Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS Epidemiology, Symptoms, and Treatment) Primary Care Study. Sleep Med 2004; 5 (3): 237-246
4. Kushida C,Martin M, Nikam P, et al. Burden of restless legs syndrome on health-related quality of life. Qual Life Res 2007; 16 (4): 617-624 (Pubitemid 46474940)
5. Happe S, Vennemann M, Evers S, et al. Treatment wish of individuals with known and unknown restless legs syndrome in the community. J Neurol 2008; 255 (9): 1365-1371
6. Walters AS, Hickey K, Maltzman J, et al. A questionnaire study of 138 patients with restless legs syndrome: the 'Night-Walkers' survey. Neurology 1996; 46 (1): 92-95 (Pubitemid 26156108)
7. Walters AS, LeBrocq C, Dhar A, et al. Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome. Sleep Med 2003; 4 (2): 121-132 (Pubitemid 36527232)
8. Johns MW. Reliability and factor analysis of the Epworth Sleepiness Scale. Sleep 1992; 15 (4): 376-381
9. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 1991; 14 (6): 540-545
10. Johns MW. Daytime sleepiness, snoring, and obstructive sleep apnea: the Epworth Sleepiness Scale. Chest 1993; 103 (1): 30-36 (Pubitemid 23027228)
11. Dixon JB, Dixon ME, Anderson ML, et al. Daytime sleepiness in the obese: not as simple as obstructive sleep apnea. Obesity (Silver Spring) 2007; 15 (10): 2504-2511 (Pubitemid 350034045)
12. Atkinson MJ, Sinha A, Hass SL, et al. Validation of a general measure of treatment satisfaction, the Treatment Satisfaction Questionnaire for Medication (TSQM), using a national panel study of chronic disease. Health Qual Life Outcomes 2004; 2 (1): 12
13. Richter P, Werner J, Bastine R, et al. Measuring treatment outcome by the Beck Depression Inventory. Psychopathology 1997; 30 (4): 234-240 (Pubitemid 27296403)
14. Folstein MF, Folstein SE,McHugh PR. 'Mini-mental state': a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12 (3): 189-198
15. Greiner W, Claes C. Der EQ-5D der EuroQol-Gruppe. Gesundheitsö konomische Evaluationen. Berlin: Springer, 2007
16. Kö nig HH, Bernert S, Angermeyer MC. Gesundheitszustand der deutschen Bevö lkerung: Ergebnisse einer reprä sentativen Befragung mit dem EuroQol-Instrument. Gesundheitswesen 2005; 67: 173-182 (Pubitemid 40523398)
17. Greiner W, Claes C, Busschbach JJ, et al. Validating the EQ-5D with time trade off for the German population. Eur J Health Econ 2005; 6 (2): 124-130 (Pubitemid 40905009)
18. Hamer HM, Spottke A, Aletsee C, et al. Direct and indirect costs of refractory epilepsy in a tertiary epilepsy center in Germany. Epilepsia 2006; 47 (12): 2165-2172 (Pubitemid 44952272)
19. Spottke AE, Reuther M, Peter H, et al. Healthcare utilization and cost of care of patients with Parkinson's disease in Germany. Pharmacoeconomics 2005; 3 (8): 817-836
20. Bundesverband der pharmazeutischen Industrie. Rote Liste. Weinheim: Rote Liste Verlag, 2006
21. Bundesministerium der Justiz. Sozialgesetzbuch I-XI. Kö ln/Limburg: Bundesanzeiger Verlag, 2003
22. InEK - Institute for the Hospital Remuneration System [online]. Available from URL: http://www.g-drg.de [Accessed 2008 Jul 1]
23. Institute for the Hospital Remuneration System [online]. Available from URL: http://www.g-drg.de [Accessed 2009 Dec 1]
24. Krauth C, Hessel F, Hansmeier T, et al. Empirical standard costs for health economic evaluation in Germany: a proposal by the working group methods in health economic evaluation. Gesundheitswesen 2005; 67 (10): 736-746 (Pubitemid 41604934)
25. Vdak. Reimbursement list for physiotherapy, massages, medical baths [in German; online]. Available from URL: http://www.kvhessen.de [Accessed 2007 Dec 1]
26. Graf Von Der Schulenburg JM, Greiner W, Jost F, et al., and the Mitglieder des Hannoveraner Konsens. German recommendations on health economic evaluation. Third updated version of the Hanover Consensus. Gesundh ö kon Qual Manag 2007; 12: 285-290
27. Statistisches Bundesamt Deutschland [online]. Available from URL: http://www.destat.de [Accessed 2009 Dec 1]
28. Borth J, Dö ring N. Forschungsmethoden und Evaluation. Heidelberg: Springer, 2006
29. Maxwell SE. Sample size and multiple regression analysis. Psychol Methods 2000; 5: 434-458
30. Lin DY. Linear regression analysis of censored medical costs. Biostatistics 2000; 1: 35-47
31. Barber JA, Thompson SG. Analysis of cost data in randomized trials: an application of the non-parametric bootstrap. Stat Med 2000; 19: 3219-3236
32. Happe S, Reese JP, Stiasny-Kolster K, et al. Assessing health-related quality of life in patients with restless legs syndrome. Sleep Med 2008; 10 (3): 295-305
33. Dodel R, Peter H, Walbert T, et al. The socioeconomic impact of narcolepsy. Sleep 2004; 27 (6): 1123-1128
34. Schepelmann K, Winter Y, Spottke AE, et al. Socioeconomic burden of amyotrophic lateral sclerosis, myasthenia gravis and facioscapulohumeral muscular dystrophy. J Neurol 2010; 257 (1): 15-23
35. Gold MR, Siegel JE, Russell LB, et al. Cost-effectiveness in health and medicine. New York: Oxford University Press, 1996
36. Reuther M, Spottke EA, Klotsche J, et al. Assessing healthrelated quality of life in patients with Parkinson's disease in a prospective longitudinal study. Parkinsonism Relat Disord 2007; 13 (2): 108-114 (Pubitemid 46329519)
37. Haacke C, Althaus A, Spottke A, et al. Long-term outcome after stroke: evaluating health-related quality of life using utility measurements. Stroke 2006; 37 (1): 193-198 (Pubitemid 43732070)
38. Henriksson F, Fredrikson S,Masterman T, et al. Costs, quality of life and disease severity in multiple sclerosis: a crosssectional study in Sweden. Eur J Neurol 2001; 8 (1): 27-35 (Pubitemid 32154571)
39. Nelles S, Koberlein J, Grimm C, et al. Socioeconomic relevance of the idiopathic restless legs syndrome (RLS) in Germany: cost-of-illness study [in German]. Med Klin (Munich) 2009; 104 (5): 363-371
40. Maurel F, Girard B, Crochard A, et al. Profile of patients suffering from restless legs syndrome and estimation of their annual cost in an ambulatory care setting in France. Value Health 2004; 7: 790-791
41. Curtice TG, Long SR, Baser O, et al. Economic burden of restless legs syndrome in a privately-insured population [abstract]. Value Health 2006; 9 (3): 74
42. Douzinas N, Connolly MP, Kirsch J, et al. Establishing the indirect costs of RLS based on severity using the international restless legs severity scale and the productivity and activity impairment [abstract]. Mov Disord 2005; 12: S62
43. Krug H. Tun oder Unterlassen. Ethik in der Medizin 2005; 17: 159-163
44. Diener HC, Putzki N. Leitlinien fü r Diagnostik und Therapie in der Neurologie. Stuttgart: Thieme, 2008
45. Liebl A, Neiss A, Spannheimer A, et al. Costs of type 2 diabetes in Germany: results of the CODE-2 study. Dtsch Med Wochenschr 2001; 126 (20): 585-9