VDAC1 cysteine residues: Topology and function in channel activity and apoptosis

Biochemical Journal

Volumn 427, Issue 3, 2010, Pages 445-454

  Aram, Lior ^a   Geula, Shay ^a   Arbel, Nir ^a   Shoshan Barmatz, Varda ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Apoptosis; Cross linking; Cysteine residue; Mitochondrion; Thiol modifying agent; Voltage dependent anion channel (VDAC)

Indexed keywords

ALANINE RESIDUES; APOPTOSIS; APOPTOSIS ACTIVITY; APOPTOTIC CELL DEATH; BI-LAYER; CHANNEL ACTIVITY; CROSS-LINKING REAGENTS; CYSTEINE RESIDUES; CYTOSOLS; HAIRPIN RNA; IN-CELL; IN-CHANNELS; LOW LEVEL; MALEIMIDES; MEMBRANE-PERMEABLE; MODIFYING AGENTS; OVER-EXPRESSION; OXIDATION STATE; REACTIVE OXYGEN SPECIES; SMALL INTERFERING RNA; VOLTAGE-DEPENDENT ANION CHANNELS;

ETHANE; IONS; LIPID BILAYERS; MITOCHONDRIA; OLIGOMERIZATION; OXYGEN; RNA; TOPOLOGY;

CELL DEATH;

5 MALEIMIDOFLUORESCEIN; ALANINE; ARSENIC TRIOXIDE; BIS(MALEIMIDO)ETHANE; CYSTEINE; FLUORESCEIN DERIVATIVE; HYDROGEN PEROXIDE; MALEIMIDE DERIVATIVE; N ETHYLMALEIMIDE; REACTIVE OXYGEN METABOLITE; SELENITE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 1; FLUORESCEIN 5-MALEIMIDE; ORGANOARSENIC DERIVATIVE; OXIDE; SODIUM SELENITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONDUCTANCE; CONTROLLED STUDY; CROSS LINKING; HUMAN; LIPID BILAYER; MITOCHONDRION; MUTATION; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; ANIMAL; CATTLE; CHEMISTRY; DRUG EFFECT; GENETICS; IMMUNOBLOTTING; METABOLISM; MITOCHONDRIAL MEMBRANE; MOUSE; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; RABBIT; STRUCTURE ACTIVITY RELATION;

RATTUS;

ANIMALS; APOPTOSIS; ARSENICALS; CATTLE; CYSTEINE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ETHYLMALEIMIDE; FLUORESCEINS; HUMANS; HYDROGEN PEROXIDE; IMMUNOBLOTTING; LIPID BILAYERS; MICE; MITOCHONDRIAL MEMBRANES; OXIDES; RABBITS; RATS; RNA, SMALL INTERFERING; SODIUM SELENITE; STRUCTURE-ACTIVITY RELATIONSHIP; VOLTAGE-DEPENDENT ANION CHANNEL 1;

EID: 77951243031     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20091690     Document Type: Article

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