Differential gene expression in drug hypersensitivity reactions: Induction of alarmins in severe bullous diseases

British Journal of Dermatology

Volumn 162, Issue 5, 2010, Pages 1014-1022

  Bellon T ^a   Alvarez L ^a   Mayorga, C ^b   Morel, E ^a   Torres, M J ^b   Martin Diaz M A ^a   Diaz R ^a   Radial, A ^a   Carballo, M ^c   Blanca, M ^b  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^b HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^c HOSPITAL DE TERRASSA   (Spain)

Author keywords

Alarmins; DAMPs (damage associated molecular patterns); Drug hypersensitivity; Stevens Johnson syndrome; Toxic epidermal necrolysis

Indexed keywords

ALARMIN; ALLOPURINOL; AMOXICILLIN; ANTICONVULSIVE AGENT; CARBAMAZEPINE; CELL CYCLE PROTEIN; CELL PROTEIN; CLINDAMYCIN; DAMAGE ASSOCIATED MOLECULAR PATTERN; DIAZEPAM; DIPYRONE; ERYTHROMYCIN; FLUINDOSTATIN; FUROSEMIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IBUPROFEN; IMATINIB; METRONIDAZOLE; PARACETAMOL; PHENYTOIN; PSEUDOEPHEDRINE; SPIRAMYCIN; TAMOXIFEN; UNCLASSIFIED DRUG; VALPROIC ACID;

ADOLESCENT; ADULT; ARTICLE; BULLOUS SKIN DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DNA MICROARRAY; DRESS SYNDROME; DRUG ERUPTION; DRUG HYPERSENSITIVITY; ERYTHEMA MULTIFORME; FEMALE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; MACULOPAPULAR RASH; MALE; MEDIATOR RELEASE; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; SENSITIZATION; STEVENS JOHNSON SYNDROME; T LYMPHOCYTE; TOXIC EPIDERMAL NECROLYSIS;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; DRUG ERUPTIONS; EPIDERMAL NECROLYSIS, TOXIC; FEMALE; GENE EXPRESSION PROFILING; GENES, CDC; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN DISEASES, VESICULOBULLOUS; STEVENS-JOHNSON SYNDROME; T-LYMPHOCYTES; UP-REGULATION;

EID: 77951239907     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2009.09627.x     Document Type: Article

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