Expression of apolipoprotein B in the kidney attenuates renal lipid accumulation

Journal of Biological Chemistry

Volumn 285, Issue 14, 2010, Pages 10583-10590

  Krzystanek, Marcin ^a   Pedersen, Tanja Xenia ^a,b   Bartels, Emil Daniel ^a   Kjæhr, Jacob ^a   Straarup, Ellen Marie ^c   Nielsen, Lars Bo ^a,b  

^a International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c Santaris Pharma AS   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; APOLIPOPROTEINS; BASE PAIRS; BIOLOGICAL EFFECTS; CARDIOMYOCYTES; CHOLESTEROL CONTENT; ENTEROCYTES; EPITHELIAL CELLS; HEPATOCYTES; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATIONS; IN-VIVO; LOCKED NUCLEIC ACID; LOW DENSITY LIPOPROTEINS; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEINS; MOUSE KIDNEY; RENAL LIPIDS; SUCROSE GRADIENTS; TRANSGENIC MICE; TUBULAR EPITHELIUM; ULTRACENTRIFUGATION; WILD TYPES;

AMINO ACIDS; CENTRIFUGATION; CHOLESTEROL; MAMMALS; NUCLEIC ACIDS; OLIGONUCLEOTIDES; ORGANIC ACIDS; PROTEINS; SUGAR (SUCROSE);

LIPIDS;

ANTISENSE OLIGONUCLEOTIDE; APOLIPOPROTEIN B; APOLIPOPROTEIN B100; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; KIDNEY CORTEX; KIDNEY TUBULE EPITHELIUM; LIPID METABOLISM; LIPID STORAGE; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; ULTRACENTRIFUGATION;

ANIMALS; APOLIPOPROTEIN B-100; APOLIPOPROTEINS B; BLOTTING, WESTERN; CHOLESTEROL; HUMANS; KIDNEY; LIPOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OLIGONUCLEOTIDES, ANTISENSE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRIGLYCERIDES;

MAMMALIA; MUS; MUS MUSCULUS;

EID: 77951236504     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.078006     Document Type: Article

References (36)

1. Young, S. G. (1990) Circulation 82, 1574-1594
2. Gregg, R. E., and Wetterau, J. R. (1994) Curr. Opin. Lipidol. 5, 81-86
3. Demmer, L. A., Levin, M. S., Elovson, J., Reuben, M. A., Lusis, A. J., and Gordon, J. I. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 8102-8106
4. Madsen, E. M., Lindegaard, M. L., Andersen, C. B., Damm, P., and Nielsen, L. B. (2004) J. Biol. Chem. 279, 55271-55276
5. Borén, J., Véniant, M. M., and Young, S. G. (1998) J. Clin. Invest. 101, 1197-1202
6. Nielsen, L. B., Véniant, M., Borén, J., Raabe, M., Wong, J. S., Tam, C., Flynn, L., Vanni-Reyes, T., Gunn, M. D., Goldberg, I. J., Hamilton, R. L., and Young, S. G. (1998) Circulation 98, 13-16
7. Nielsen, L. B., Bartels, E. D., and Bollano, E. (2002) J. Biol. Chem. 277, 27014-27020
8. Bartels, E. D., Nielsen, J. M., Hellgren, L. I., Ploug, T., and Nielsen, L. B. (2009) PLoS One 4, e5300
9. Fujihara, M., Bartels, E., Nielsen, L. B., and Handa, J. T. (2009) Exp. Eye Res. 88, 1115-1123
10. Walzem, R. L., Hansen, R. J., Williams, D. L., and Hamilton, R. L. (1999) J. Nutr. 129, 467S-472S
11. Tarugi, P., Ballarini, G., Pinotti, B., Franchini, A., Ottaviani, E., and Calandra, S. (1998) J. Lipid Res. 39, 731-743
12. Wetterau, J. R., and Zilversmit, D. B. (1986) Biochim. Biophys. Acta 875, 610-617
13. Zager, R. A., Johnson, A. C., and Hanson, S. Y. (2005) Kidney Int. 67, 111-121
14. Portilla, D., Li, S., Nagothu, K. K., Megyesi, J., Kaissling, B., Schnackenberg, L., Safirstein, R. L., and Beger, R. D. (2006) Kidney Int. 69, 2194-2204
15. Portilla, D., Dai, G., McClure, T., Bates, L., Kurten, R., Megyesi, J., Price, P., and Li, S. (2002) Kidney Int. 62, 1208-1218
16. Fruchart, J. C. (2009) Atherosclerosis 205, 1-8
17. Li, S., Wu, P., Yarlagadda, P., Vadjunec, N. M., Proia, A. D., Harris, R. A., and Portilla, D. (2004) Am. J. Physiol. Renal Physiol. 286, F572-F580
18. Michalik, L., and Wahli, W. (2006) J. Clin. Invest. 116, 598-606
19. Bartels, E. D., Nielsen, J. E., Lindegaard, M. L., Hulten, L. M., Schroeder, T. V., and Nielsen, L. B. (2007) Atherosclerosis 195, e42-e49
20. Christoffersen, C., Bollano, E., Lindegaard, M. L., Bartels, E. D., Goetze, J. P., Andersen, C. B., and Nielsen, L. B. (2003) Endocrinology 144, 3483-3490
21. Bang, C. A., Bro, S., Bartels, E. D., Pedersen, T. X., and Nielsen, L. B. (2007) Am. J. Physiol. Renal Physiol. 293, F1325-F1331
22. Lindegaard, M. L., and Nielsen, L. B. (2008) Metabolism 57, 766-773
23. Nielsen, L. B., McCormick, S. P., Pierotti, V., Tam, C., Gunn, M. D., Shizuya, H., and Young, S. G. (1997) J. Biol. Chem. 272, 29752-29758
24. Bartels, E. D., Lauritsen, M., and Nielsen, L. B. (2002) Diabetes 51, 1233-1239
25. Linton, M. F., Farese, R. V., Jr., Chiesa, G., Grass, D. S., Chin, P., Hammer, R. E., Hobbs, H. H., and Young, S. G. (1993) J. Clin. Invest. 92, 3029-3037
26. Birn, H., and Christensen, E. I. (2006) Kidney Int. 69, 440-449
27. Tan, M. H., Sata, T., and Havel, R. J. (1977) J. Lipid Res. 18, 363-370
28. Ladu, M. J., Kapsas, H., and Palmer, W. K. (1991) Am. J. Physiol. 260, R953-R959
29. Ong, J. M., Simsolo, R. B., Saghizadeh, M., Pauer, A., and Kern, P. A. (1994) J. Lipid Res. 35, 1542-1551
30. Christensen, E. I., Moskaug, J. O., Vorum, H., Jacobsen, C., Gundersen, T. E., Nykjaer, A., Blomhoff, R., Willnow, T. E., and Moestrup, S. K. (1999) J. Am. Soc. Nephrol. 10, 685-695
31. Shimabukuro, M., Zhou, Y. T., Levi, M., and Unger, R. H. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 2498-2502
32. Obeid, L. M., Linardic, C. M., Karolak, L. A., and Hannun, Y. A. (1993) Science 259, 1769-1771
33. Shimabukuro, M., Zhou, Y. T., Lee, Y., and Unger, R. H. (1998) J. Biol. Chem. 273, 3547-3550
34. Unger, R. H. (2002) Annu. Rev. Med. 53, 319-336
35. Schrauwen, P. (2007) Proc. Nutr. Soc. 66, 33-41
36. Ledmyr, H., McMahon, A. D., Ehrenborg, E., Nielsen, L. B., Neville, M., Lithell, H., MacFarlane, P. W., Packard, C. J., and Karpe, F. (2004) Circulation 109, 2279-2284