Hemeoxygenase-1 and renal ischaemia-reperfusion injury

Nephron - Experimental Nephrology

Volumn 115, Issue 3, 2010, Pages

  Ferenbach, David A ^a   Kluth, David C ^a   Hughes, Jeremy ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Acute kidney injury; Hemeoxygenase 1

Indexed keywords

ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR AP 2; BILIVERDIN; CARBON MONOXIDE;

APOPTOSIS; BILE DUCT LIGATION; CAPILLARY FLOW; CD8+ T LYMPHOCYTE; CELL SURVIVAL; CREATININE CLEARANCE; GENETIC TRANSCRIPTION; GLOMERULUS FILTRATION RATE; HEAT SHOCK; HEMODYNAMICS; HUMAN; HYPOXIA; IMMUNOMODULATION; KIDNEY; KIDNEY ALLOGRAFT; KIDNEY BIOPSY; KIDNEY BLOOD FLOW; KIDNEY FUNCTION; KIDNEY ISCHEMIA; KUPFFER CELL; MACROPHAGE; MICROCIRCULATION; MICROSCOPY; ORGAN PERFUSION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION INJURY; SHORT SURVEY; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION; UPREGULATION; VASOCONSTRICTION; VASODILATATION; ACUTE KIDNEY INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; ENZYMOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ANIMALS; APOPTOSIS; BILIVERDINE; CARBON MONOXIDE; HEME OXYGENASE-1; HUMANS; KIDNEY; KIDNEY FAILURE, ACUTE; REPERFUSION INJURY; UP-REGULATION; ACUTE KIDNEY INJURY;

EID: 77951234279     PISSN: 16602129     EISSN: None     Source Type: Journal    
DOI: 10.1159/000313828     Document Type: Short Survey

References (27)

1. Wagener FA, Volk HD, Willis D, Abraham NG, Soares MP, Adema GJ, Figdor CG: Different faces of the heme-heme oxygenase system in inflammation. Pharmacol Rev 2003; 55: 551-571.
2. Morimoto K, Ohta K, Yachie A, Yang Y, Shimizu M, Goto C, Toma T, Kasahara Y, Yokoyama H, Miyata T, Seki H, Koizumi S: Cytoprotective role of heme oxygenase (HO)-1 in human kidney with various renal diseases. Kidney Int 2001; 60: 1858-1866.
3. Koizumi S: Human heme oxygenase-1 deficiency: a lesson on serendipity in the discovery of the novel disease. Pediatr Int 2007; 49: 125-132.
4. Nath KA, Balla G, Vercellotti GM, Balla J, Jacob HS, Levitt MD, Rosenberg ME: Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat. J Clin Invest 1992; 90: 267-270.
5. Pittock ST, Norby SM, Grande JP, Croatt AJ, Bren GD, Badley AD, Caplice NM, Griffin MD, Nath KA: MCP-1 is up-regulated in unstressed and stressed HO-1 knockout mice: pathophysiologic correlates. Kidney Int 2005; 68: 611-622.
6. Shiraishi F, Curtis LM, Truong L, Poss K, Visner GA, Madsen K, Nick HS, Agarwal A: Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis. Am J Physiol Renal Physiol 2000; 278:F726-F736. (Pubitemid 30351074)
7. Nath KA, Haggard JJ, Croatt AJ, Grande JP, Poss KD, Alam J: The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo. Am J Pathol 2000; 156: 1527-1535.
8. Maines MD, Mayer RD, Ewing JF, Mc-Coubrey WK Jr: Induction of kidney heme oxygenase-1 (HSP32) mRNA and protein by ischemia/reperfusion: possible role of heme as both promotor of tissue damage and regulator of HSP32. J Pharmacol Exp Ther 1993; 264: 457-462.
9. Ollinger R, Kogler P, Biebl M, Sieb M, Sucher R, Bösmüller C, Troppmair J, Mark W, Weiss H, Margreiter R: Protein levels of heme oxygenase-1 during reperfusion in human kidney transplants with delayed graft function. Clin Transplant 2008; 22: 418-423.
10. Nath KA: Heme oxygenase-1: a provenance for cytoprotective pathways in the kidney and other tissues. Kidney Int 2006; 70: 432-443.
11. Sikorski EM, Hock T, Hill-Kapturczak N, Agarwal A: The story so far: molecular regulation of the heme oxygenase-1 gene in renal injury. Am J Physiol Renal Physiol 2004; 286:F425-F441.
12. Leonard MO, Kieran NE, Howell K, Burne MJ, Varadarajan R, Dhakshinamoorthy S, Porter AG, O'Farrelly C, Rabb H, Taylor CT: Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemiareperfusion injury. FASEB J 2006; 20: 2624-2626.
13. Appleton SD, Chretien ML, McLaughlin BE, Vreman HJ, Stevenson DK, Brien JF, Nakatsu K, Maurice DH, Marks GS: Selective inhibition of heme oxygenase, without inhibition of nitric oxide synthase or soluble guanylyl cyclase, by metalloporphyrins at low concentrations. Drug Metab Dispos 1999; 27: 1214-1219.
14. Vera T, Henegar JR, Drummond HA, Rimoldi JM, Stec DE: Protective effect of carbon monoxide-releasing compounds in ischemia- induced acute renal failure. J Am Soc Nephrol 2005; 16: 950-958.
15. Zou AP, Billington H, Su N, Cowley AW Jr: Expression and actions of heme oxygenase in the renal medulla of rats. Hypertension 2000; 35: 342-347.
16. Hölzen JP, August C, Bahde R, Minin E, Lang D, Heidenreich S, Dietl KH, Spiegel HU: Influence of heme oxygenase-1 on microcirculation after kidney transplantation. J Surg Res 2008; 148: 126-135.
17. Chlopicki S, Olszanecki R, Marcinkiewicz E, Lomnicka M, Motterlini R: Carbon monoxide released by CORM-3 inhibits human platelets by a mechanism independent of soluble guanylate cyclase. Cardiovasc Res 2006; 71: 393-401.
18. Bagul A, Hosgood SA, Kaushik M, Nicholson ML: Carbon monoxide protects against ischemia- reperfusion injury in an experimental model of controlled nonheartbeating donor kidney. Transplantation 2008; 85: 576-581.
19. Ren Y, D'Ambrosio MA, Wang H, Liu R, Garvin JL, Carretero OA: Heme oxygenase metabolites inhibit tubuloglomerular feedback (TGF). Am J Physiol Renal Physiol 2008; 295:F1207-F1212.
20. Nakao A, Neto JS, Kanno S, Stolz DB, Kimizuka K, Liu F, Bach FH, Billiar TR, Choi AM, Otterbein LE, Murase N: Protection against ischemia-reperfusion injury in cardiac and renal transplantation with carbon monoxide, biliverdin and both. Am J Transplant 2005; 5: 282-291.
21. Brouard S, Otterbein LE, Anrather J, Tobiasch E, Bach FH, Choi AM, Soares MP: Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis. J Exp Med 2000; 192: 1015-1026.
22. Inguaggiato P, Gonzalez-Michaca L, Croatt AJ, Haggard JJ, Alam J, Nath KA: Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis. Kidney Int 2001; 60: 2181-2191.
23. Devey L, Ferenbach D, Mohr E, Sangster K, Bellamy CO, Hughes J, Wigmore SJ: Tissueresident macrophages protect the liver from ischemia-reperfusion injury via a heme oxygenase- 1-dependent mechanism. Mol Ther 2009; 17: 65-72.
24. Gueler F, Park JK, Rong S, Kirsch T, Lindschau C, Zheng W, Elger M, Fiebeler A, Fliser D, Luft FC, Haller H: Statins attenuate ischemia-reperfusion injury by inducing heme oxygenase-1 in infiltrating macrophages. Am J Pathol 2007; 170: 1192-1199.
25. Andersen MH: Identification of heme oxygenase- 1' specific regulatory CD8+ T cells in cancer patients. J Clin Invest 2009; 119: 2245-2256.
26. George JF, Braun A, Brusko TM, Joseph R, Bolisetty S, Wasserfall CH, Atkinson MA, Agarwal A, Kapturczak MH: Suppression by CD4+CD25+ regulatory T cells is dependent on expression of heme oxygenase-1 in antigen- presenting cells. Am J Pathol 2008; 173: 154-160.
27. Fellstrom B, Holdaas H, Jardine AG, Holme I, Nyberg G, Fauchald P, Gronhagen-Riska C, Madsen S, Neumayer HH, Cole E, Maes B, Ambuhl P, Olsson AG, Hartmann A, Logan JO, Pedersen TR: Effect of fluvastatin on renal end points in the Assessment of Lescol in Renal Transplant (ALERT) trial. Kidney Int 2004; 66: 1549-1555.