-
1
-
-
0036285634
-
Mathematical models of protein kinase signal transduction
-
DOI 10.1016/S1097-2765(02)00528-2
-
Heinrich, R., Neel, B. G. and Rapoport, T. A. (2002) Mathematical models of protein kinase signal transduction. Mol. Cell 9, 957-970 (Pubitemid 34626667)
-
(2002)
Molecular Cell
, vol.9
, Issue.5
, pp. 957-970
-
-
Heinrich, R.1
Neel, B.G.2
Rapoport, T.A.3
-
2
-
-
11444260258
-
Principles behind the multifarious control of signal transduction. ERK phosphorylation and kinase/phosphatase control
-
Hornberg, J. J., Bruggeman, F. J., Binder, B., Geest, C. R., de Vaate, A. J., Lankelma, J., Heinrich, R. and Westerhoff, H. V. (2005) Principles behind the multifarious control of signal transduction. ERK phosphorylation and kinase/phosphatase control. FEBS J. 272, 244-258
-
(2005)
FEBS J.
, vol.272
, pp. 244-258
-
-
Hornberg, J.J.1
Bruggeman, F.J.2
Binder, B.3
Geest, C.R.4
De Vaate, A.J.5
Lankelma, J.6
Heinrich, R.7
Westerhoff, H.V.8
-
3
-
-
33750299450
-
Protein tyrosine phosphatases: From genes, to function, to disease
-
Tonks, N. K. (2006) Protein tyrosine phosphatases: from genes, to function, to disease. Nat. Rev. Mol. Cell Biol. 7, 833-846
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 833-846
-
-
Tonks, N.K.1
-
4
-
-
0031686611
-
Gathering STYX: Phosphatase-like form predicts functions for unique protein-interaction domains
-
Wishart, M. J. and Dixon, J. E. (1998) Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains. Trends Biochem. Sci. 23, 301-306
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 301-306
-
-
Wishart, M.J.1
Dixon, J.E.2
-
5
-
-
70350324906
-
Pseudophosphatases: Grab and hold on
-
Tonks, N. K. (2009) Pseudophosphatases: grab and hold on. Cell 139, 464-465
-
(2009)
Cell
, vol.139
, pp. 464-465
-
-
Tonks, N.K.1
-
6
-
-
33746353046
-
LKB1-dependent signaling pathways
-
Alessi, D. R., Sakamoto, K. and Bayascas, J. R. (2006) LKB1-dependent signaling pathways. Annu. Rev. Biochem. 75, 137-163
-
(2006)
Annu. Rev. Biochem.
, vol.75
, pp. 137-163
-
-
Alessi, D.R.1
Sakamoto, K.2
Bayascas, J.R.3
-
7
-
-
0028818834
-
A single mutation converts a novel phosphotyrosine binding domain into a dual-specificity phosphatase
-
Wishart, M. J., Denu, J. M., Williams, J. A. and Dixon, J. E. (1995) A single mutation converts a novel phosphotyrosine binding domain into a dual-specificity phosphatase. J. Biol. Chem. 270, 26782-26785
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26782-26785
-
-
Wishart, M.J.1
Denu, J.M.2
Williams, J.A.3
Dixon, J.E.4
-
8
-
-
10644268691
-
Substrate-trapping techniques in the identification of cellular PTP targets
-
Blanchetot, C., Chagnon, M., Dube, N., Halle, M. and Tremblay, M. L. (2005) Substrate-trapping techniques in the identification of cellular PTP targets. Methods 35, 44-53
-
(2005)
Methods
, vol.35
, pp. 44-53
-
-
Blanchetot, C.1
Chagnon, M.2
Dube, N.3
Halle, M.4
Tremblay, M.L.5
-
9
-
-
0031055324
-
Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases
-
Flint, A. J., Tiganis, T., Barford, D. and Tonks, N. K. (1997) Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases. Proc. Natl. Acad. Sci. U.S.A. 94, 1680-1685
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 1680-1685
-
-
Flint, A.J.1
Tiganis, T.2
Barford, D.3
Tonks, N.K.4
-
10
-
-
0037133166
-
The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production
-
Wishart, M. J. and Dixon, J. E. (2002) The archetype STYX/dead- phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. Proc. Natl. Acad. Sci. U.S.A. 99, 2112-2117
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 2112-2117
-
-
Wishart, M.J.1
Dixon, J.E.2
-
11
-
-
0032167450
-
IA-2 (islet cell antigen 512) is the primary target of humoral autoimmunity against type 1 diabetes-associated tyrosine phosphatase autoantigens
-
Bonifacio, E., Lampasona, V. and Bingley, P. J. (1998) IA-2 (islet cell antigen 512) is the primary target of humoral autoimmunity against type 1 diabetes-associated tyrosine phosphatase autoantigens. J. Immunol. 161, 2648-2654 (Pubitemid 28397086)
-
(1998)
Journal of Immunology
, vol.161
, Issue.5
, pp. 2648-2654
-
-
Bonifacio, E.1
Lampasona, V.2
Bingley, P.J.3
-
12
-
-
33847014189
-
Crystal structure of the major diabetes autoantigen insulinoma-associated protein 2 reveals distinctive immune epitopes
-
Kim, S. J., Jeong, D. G., Jeong, S. K., Yoon, T. S. and Ryu, S. E. (2007) Crystal structure of the major diabetes autoantigen insulinoma-associated protein 2 reveals distinctive immune epitopes. Diabetes 56, 41-48
-
(2007)
Diabetes
, vol.56
, pp. 41-48
-
-
Kim, S.J.1
Jeong, D.G.2
Jeong, S.K.3
Yoon, T.S.4
Ryu, S.E.5
-
13
-
-
69249208637
-
Expression and function of IA-2 family proteins, unique neuroendocrine-specific protein-tyrosine phosphatases
-
Torii, S. (2009) Expression and function of IA-2 family proteins, unique neuroendocrine-specific protein-tyrosine phosphatases. Endocr. J. 56, 639-648
-
(2009)
Endocr. J.
, vol.56
, pp. 639-648
-
-
Torii, S.1
-
14
-
-
0042847303
-
A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2β)
-
Drake, P. G., Peters, G. H., Andersen, H. S., Hendriks, W. and Moller, N. P. (2003) A novel strategy for the development of selective active-site inhibitors of the protein tyrosine phosphatase-like proteins islet-cell antigen 512 (IA-2) and phogrin (IA-2β). Biochem. J. 373, 393-401
-
(2003)
Biochem. J.
, vol.373
, pp. 393-401
-
-
Drake, P.G.1
Peters, G.H.2
Andersen, H.S.3
Hendriks, W.4
Moller, N.P.5
-
15
-
-
28444483946
-
The IA-2 interactome
-
Hu, Y. F., Zhang, H. L., Cai, T., Harashima, S. and Notkins, A. L. (2005) The IA-2 interactome. Diabetologia 48, 2576-2581
-
(2005)
Diabetologia
, vol.48
, pp. 2576-2581
-
-
Hu, Y.F.1
Zhang, H.L.2
Cai, T.3
Harashima, S.4
Notkins, A.L.5
-
16
-
-
0033553515
-
Crystal structure of the tandem phosphatase domains of RPTP LAR
-
Nam, H. J., Poy, F., Krueger, N. X., Saito, H. and Frederick, C. A. (1999) Crystal structure of the tandem phosphatase domains of RPTP LAR. Cell 97, 449-457
-
(1999)
Cell
, vol.97
, pp. 449-457
-
-
Nam, H.J.1
Poy, F.2
Krueger, N.X.3
Saito, H.4
Frederick, C.A.5
-
17
-
-
52949127317
-
The JAK kinases: Not just another kinase drug discovery target
-
Wilks, A. F. (2008) The JAK kinases: not just another kinase drug discovery target. Semin. Cell Dev. Biol. 19, 319-328
-
(2008)
Semin. Cell Dev. Biol.
, vol.19
, pp. 319-328
-
-
Wilks, A.F.1
-
18
-
-
1242342002
-
Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases
-
Persson, C., Sjoblom, T., Groen, A., Kappert, K., Engstrom, U., Hellman, U., Heldin, C. H., den Hertog, J. and Ostman, A. (2004) Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases. Proc. Natl. Acad. Sci. U.S.A. 101, 1886-1891
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 1886-1891
-
-
Persson, C.1
Sjoblom, T.2
Groen, A.3
Kappert, K.4
Engstrom, U.5
Hellman, U.6
Heldin, C.H.7
Den Hertog, J.8
Ostman, A.9
-
19
-
-
70350344970
-
Regulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transition
-
Cheng, K. C., Klancer, R., Singson, A. and Seydoux, G. (2009) Regulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transition. Cell 139, 560-572
-
(2009)
Cell
, vol.139
, pp. 560-572
-
-
Cheng, K.C.1
Klancer, R.2
Singson, A.3
Seydoux, G.4
-
20
-
-
27944470541
-
The structure and regulation of myotubularin phosphatases
-
Begley, M. J. and Dixon, J. E. (2005) The structure and regulation of myotubularin phosphatases. Curr. Opin. Struct. Biol. 15, 614-620
-
(2005)
Curr. Opin. Struct. Biol.
, vol.15
, pp. 614-620
-
-
Begley, M.J.1
Dixon, J.E.2
-
21
-
-
33746729798
-
Myotubularin phosphatases: Policing 3-phosphoinositides
-
Robinson, F. L. and Dixon, J. E. (2006) Myotubularin phosphatases: policing 3-phosphoinositides. Trends Cell Biol. 16, 403-412
-
(2006)
Trends Cell Biol.
, vol.16
, pp. 403-412
-
-
Robinson, F.L.1
Dixon, J.E.2
-
22
-
-
24744446022
-
The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease
-
Robinson, F. L. and Dixon, J. E. (2005) The phosphoinositide-3- phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease. J. Biol. Chem. 280, 31699-31707
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31699-31707
-
-
Robinson, F.L.1
Dixon, J.E.2
-
23
-
-
0038744272
-
Mutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucoma
-
Azzedine, H., Bolino, A., Taieb, T., Birouk, N., Di Duca, M., Bouhouche, A., Benamou, S., Mrabet, A., Hammadouche, T., Chkili, T. et al. (2003) Mutations in MTMR13, a new pseudophosphatase homologue of MTMR2 and Sbf1, in two families with an autosomal recessive demyelinating form of Charcot-Marie-Tooth disease associated with early-onset glaucoma. Am. J. Hum. Genet. 72, 1141-1153
-
(2003)
Am. J. Hum. Genet.
, vol.72
, pp. 1141-1153
-
-
Azzedine, H.1
Bolino, A.2
Taieb, T.3
Birouk, N.4
Di Duca, M.5
Bouhouche, A.6
Benamou, S.7
Mrabet, A.8
Hammadouche, T.9
Chkili, T.10
-
24
-
-
17044370533
-
EWS-FLI1 target genes recovered from Ewing's sarcoma chromatin
-
Siligan, C., Ban, J., Bachmaier, R., Spahn, L., Kreppel, M., Schaefer, K. L., Poremba, C., Aryee, D. N. and Kovar, H. (2005) EWS-FLI1 target genes recovered from Ewing's sarcoma chromatin. Oncogene 24, 2512-2524
-
(2005)
Oncogene
, vol.24
, pp. 2512-2524
-
-
Siligan, C.1
Ban, J.2
Bachmaier, R.3
Spahn, L.4
Kreppel, M.5
Schaefer, K.L.6
Poremba, C.7
Aryee, D.N.8
Kovar, H.9
-
25
-
-
34248595035
-
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases
-
Owens, D. M. and Keyse, S. M. (2007) Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases. Oncogene 26, 3203-3213
-
(2007)
Oncogene
, vol.26
, pp. 3203-3213
-
-
Owens, D.M.1
Keyse, S.M.2
-
26
-
-
13144276292
-
Rasputin, more promiscuous than ever: A review of G3BP
-
Irvine, K., Stirling, R., Hume, D. and Kennedy, D. (2004) Rasputin, more promiscuous than ever: a review of G3BP. Int. J. Dev. Biol. 48, 1065-1077
-
(2004)
Int. J. Dev. Biol.
, vol.48
, pp. 1065-1077
-
-
Irvine, K.1
Stirling, R.2
Hume, D.3
Kennedy, D.4
-
27
-
-
0030837555
-
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
-
Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R. and Tonks, N. K. (1997) P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc. Natl. Acad. Sci. U.S.A. 94, 9052-9057
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 9052-9057
-
-
Myers, M.P.1
Stolarov, J.P.2
Eng, C.3
Li, J.4
Wang, S.I.5
Wigler, M.H.6
Parsons, R.7
Tonks, N.K.8
-
28
-
-
0029894045
-
A Ras-GTPase-activating protein SH3-domain-binding protein
-
Parker, F., Maurier, F., Delumeau, I., Duchesne, M., Faucher, D., Debussche, L., Dugue, A., Schweighoffer, F. and Tocque, B. (1996) A Ras-GTPase-activating protein SH3-domain-binding protein. Mol. Cell. Biol. 16, 2561-2569
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2561-2569
-
-
Parker, F.1
Maurier, F.2
Delumeau, I.3
Duchesne, M.4
Faucher, D.5
Debussche, L.6
Dugue, A.7
Schweighoffer, F.8
Tocque, B.9
-
29
-
-
0037451173
-
The RasGAP-associated endoribonuclease G3BP assembles stress granules
-
Tourriere, H., Chebli, K., Zekri, L., Courselaud, B., Blanchard, J. M., Bertrand, E. and Tazi, J. (2003) The RasGAP-associated endoribonuclease G3BP assembles stress granules. J. Cell Biol. 160, 823-831
-
(2003)
J. Cell Biol.
, vol.160
, pp. 823-831
-
-
Tourriere, H.1
Chebli, K.2
Zekri, L.3
Courselaud, B.4
Blanchard, J.M.5
Bertrand, E.6
Tazi, J.7
-
30
-
-
0034090970
-
Rasputin, the Drosophila homologue of the RasGAP SH3 binding protein, functions in Ras- And Rho-mediated signaling
-
Pazman, C., Mayes, C. A., Fanto, M., Haynes, S. R. and Mlodzik, M. (2000) Rasputin, the Drosophila homologue of the RasGAP SH3 binding protein, functions in Ras- and Rho-mediated signaling. Development 127, 1715-1725 (Pubitemid 30234928)
-
(2000)
Development
, vol.127
, Issue.8
, pp. 1715-1725
-
-
Pazman, C.1
Mayes, C.A.2
Fanto, M.3
Haynes, S.R.4
Mlodzik, M.5
-
31
-
-
0031832234
-
A novel phosphorylation-dependent RNase activity of GAP-SH3 binding protein: A potential link between signal transduction and RNA stability
-
Gallouzi, I. E., Parker, F., Chebli, K., Maurier, F., Labourier, E., Barlat, I., Capony, J. P., Tocque, B. and Tazi, J. (1998) A novel phosphorylation-dependent RNase activity of GAP-SH3 binding protein: a potential link between signal transduction and RNA stability. Mol. Cell. Biol. 18, 3956-3965
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3956-3965
-
-
Gallouzi, I.E.1
Parker, F.2
Chebli, K.3
Maurier, F.4
Labourier, E.5
Barlat, I.6
Capony, J.P.7
Tocque, B.8
Tazi, J.9
-
32
-
-
0034775591
-
RasGAP-associated endoribonuclease G3Bp: Selective RNA degradation and phosphorylation-dependent localization
-
Tourriere, H., Gallouzi, I. E., Chebli, K., Capony, J. P., Mouaikel, J., van der Geer, P. and Tazi, J. (2001) RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization. Mol. Cell. Biol. 21, 7747-7760
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7747-7760
-
-
Tourriere, H.1
Gallouzi, I.E.2
Chebli, K.3
Capony, J.P.4
Mouaikel, J.5
Van Der Geer, P.6
Tazi, J.7
-
33
-
-
0036494178
-
Heregulin induces expression, ATPase activity, and nuclear localization of G3BP, a Ras signaling component, in human breast tumors
-
Barnes, C. J., Li, F., Mandal, M., Yang, Z., Sahin, A. A. and Kumar, R. (2002) Heregulin induces expression, ATPase activity, and nuclear localization of G3BP, a Ras signaling component, in human breast tumors. Cancer Res. 62, 1251-1255
-
(2002)
Cancer Res.
, vol.62
, pp. 1251-1255
-
-
Barnes, C.J.1
Li, F.2
Mandal, M.3
Yang, Z.4
Sahin, A.A.5
Kumar, R.6
-
34
-
-
0035951694
-
G3BP is overexpressed in human tumors and promotes S phase entry
-
Guitard, E., Parker, F., Millon, R., Abecassis, J. and Tocque, B. (2001) G3BP is overexpressed in human tumors and promotes S phase entry. Cancer Lett. 162, 213-221
-
(2001)
Cancer Lett.
, vol.162
, pp. 213-221
-
-
Guitard, E.1
Parker, F.2
Millon, R.3
Abecassis, J.4
Tocque, B.5
-
35
-
-
22344455246
-
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling
-
Kedersha, N., Stoecklin, G., Ayodele, M., Yacono, P., Lykke-Andersen, J., Fritzler, M. J., Scheuner, D., Kaufman, R. J., Golan, D. E. and Anderson, P. (2005) Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J. Cell. Biol. 169, 871-884
-
(2005)
J. Cell. Biol.
, vol.169
, pp. 871-884
-
-
Kedersha, N.1
Stoecklin, G.2
Ayodele, M.3
Yacono, P.4
Lykke-Andersen, J.5
Fritzler, M.J.6
Scheuner, D.7
Kaufman, R.J.8
Golan, D.E.9
Anderson, P.10
-
36
-
-
0036703286
-
mRNA degradation machines in eukaryotic cells
-
Tourriere, H., Chebli, K. and Tazi, J. (2002) mRNA degradation machines in eukaryotic cells. Biochimie 84, 821-837
-
(2002)
Biochimie
, vol.84
, pp. 821-837
-
-
Tourriere, H.1
Chebli, K.2
Tazi, J.3
-
37
-
-
0033611157
-
RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2? To the assembly of mammalian stress granules
-
Kedersha, N. L., Gupta, M., Li, W., Miller, I. and Anderson, P. (1999) RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2? to the assembly of mammalian stress granules. J. Cell. Biol. 147, 1431-1442
-
(1999)
J. Cell. Biol.
, vol.147
, pp. 1431-1442
-
-
Kedersha, N.L.1
Gupta, M.2
Li, W.3
Miller, I.4
Anderson, P.5
-
38
-
-
19844376984
-
Modulation of specific protein expression levels by PTEN: Identification of AKAP121, DHFR, G3BP, Rap1, and RCC1 as potential targets of PTEN
-
Huang, Y., Wernyj, R. P., Norton, D. D., Precht, P., Seminario, M. C. and Wange, R. L. (2005) Modulation of specific protein expression levels by PTEN: identification of AKAP121, DHFR, G3BP, Rap1, and RCC1 as potential targets of PTEN. Oncogene 24, 3819-3829
-
(2005)
Oncogene
, vol.24
, pp. 3819-3829
-
-
Huang, Y.1
Wernyj, R.P.2
Norton, D.D.3
Precht, P.4
Seminario, M.C.5
Wange, R.L.6
-
39
-
-
34250800880
-
Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP)
-
Kim, M. M., Wiederschain, D., Kennedy, D., Hansen, E. and Yuan, Z. M. (2007) Modulation of p53 and MDM2 activity by novel interaction with Ras-GAP binding proteins (G3BP). Oncogene 26, 4209-4215
-
(2007)
Oncogene
, vol.26
, pp. 4209-4215
-
-
Kim, M.M.1
Wiederschain, D.2
Kennedy, D.3
Hansen, E.4
Yuan, Z.M.5
-
40
-
-
55549130760
-
Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways
-
Arimoto, K., Fukuda, H., Imajoh-Ohmi, S., Saito, H. and Takekawa, M. (2008) Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways. Nat. Cell Biol. 10, 1324-1332
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 1324-1332
-
-
Arimoto, K.1
Fukuda, H.2
Imajoh-Ohmi, S.3
Saito, H.4
Takekawa, M.5
|