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Volumn 183, Issue 8, 2009, Pages 5171-5179

CCR7 deficiency on dendritic cells enhances fungal clearance in a murine model of pulmonary invasive aspergillosis

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR7; CXCL2 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; TUMOR NECROSIS FACTOR ALPHA;

EID: 77951217197     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901027     Document Type: Article
Times cited : (24)

References (47)
  • 1
    • 0017082126 scopus 로고
    • Sources and incidence of airborne Aspergillus fumigatus (Fres)
    • Mullins, J., R. Harvey, and A. Seaton. 1976. Sources and incidence of airborne Aspergillus fumigatus (Fres). Clin. Allergy 6: 209-217.
    • (1976) Clin. Allergy , vol.6 , pp. 209-217
    • Mullins, J.1    Harvey, R.2    Seaton, A.3
  • 3
    • 0036283440 scopus 로고    scopus 로고
    • The clinical spectrum of pulmonary aspergillosis
    • Soubani, A. O., and P. H. Chandrasekar. 2002. The clinical spectrum of pulmonary aspergillosis. Chest 121: 1988-1999.
    • (2002) Chest , vol.121 , pp. 1988-1999
    • Soubani, A.O.1    Chandrasekar, P.H.2
  • 4
    • 53349157204 scopus 로고    scopus 로고
    • Epidemiology of invasive mold infections in allogeneic stem cell transplant recipients: Biological risk factors for infection according to time after transplantation
    • Garcia-Vidal, C., A. Upton, K. A. Kirby, and K. A. Marr. 2008. Epidemiology of invasive mold infections in allogeneic stem cell transplant recipients: biological risk factors for infection according to time after transplantation. Clin. Infect. Dis. 47: 1041-1050.
    • (2008) Clin. Infect. Dis. , vol.47 , pp. 1041-1050
    • Garcia-Vidal, C.1    Upton, A.2    Kirby, K.A.3    Marr, K.A.4
  • 5
    • 0036953199 scopus 로고    scopus 로고
    • Aspergillus infections in allogeneic stem cell transplant recipients: Have we made any progress?
    • Jantunen, E., V. J. Anttila, and T. Ruutu. 2002. Aspergillus infections in allogeneic stem cell transplant recipients: have we made any progress? Bone Marrow Transplant. 30: 925-929.
    • (2002) Bone Marrow Transplant. , vol.30 , pp. 925-929
    • Jantunen, E.1    Anttila, V.J.2    Ruutu, T.3
  • 6
    • 34547759757 scopus 로고    scopus 로고
    • Invasive fungal infections in allogeneic and autologous stem cell transplant recipients: A single-center study of 166 transplanted patients
    • Post, M. J., C. Lass-Floerl, G. Gastl, and D. Nachbaur. 2007. Invasive fungal infections in allogeneic and autologous stem cell transplant recipients: a single-center study of 166 transplanted patients. Transpl. Infect. Dis. 9: 189-195.
    • (2007) Transpl. Infect. Dis. , vol.9 , pp. 189-195
    • Post, M.J.1    Lass-Floerl, C.2    Gastl, G.3    Nachbaur, D.4
  • 7
    • 1542674589 scopus 로고    scopus 로고
    • Immunity to fungal infections
    • Romani, L. 2004. Immunity to fungal infections. Nat. Rev. Immunol. 4: 1-23.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 1-23
    • Romani, L.1
  • 8
    • 0021350050 scopus 로고
    • Prolonged granulocytopenia: The major risk factor for invasive pulmonary aspergillosis in patients with acute leukemia
    • Gerson, S. L., G. H. Talbot, S. Hurwitz, B. L. Strom, E. J. Lusk, and P. A. Cassileth. 1984. Prolonged granulocytopenia: the major risk factor for invasive pulmonary aspergillosis in patients with acute leukemia. Ann. Intern. Med. 100: 345-351. (Pubitemid 14156535)
    • (1984) Annals of Internal Medicine , vol.100 , Issue.3 , pp. 345-351
    • Gerson, S.L.1    Talbot, G.H.2    Hurwitz, S.3
  • 10
    • 0346059732 scopus 로고    scopus 로고
    • Chemokine-mediated recruitment of NK cells is a critical host defense mechanism in invasive aspergillosis
    • Morrison, B. E., S. J. Park, J. M. Mooney, and B. Mehrad. 2003. Chemokine-mediated recruitment of NK cells is a critical host defense mechanism in invasive aspergillosis. J. Clin. Invest. 112: 1862-1870.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1862-1870
    • Morrison, B.E.1    Park, S.J.2    Mooney, J.M.3    Mehrad, B.4
  • 12
    • 0036467527 scopus 로고    scopus 로고
    • Dendritic cells transport conidia and hyphae of Aspergillus fumigatus from the airways to the draining lymph nodes and initiate disparate Th responses to the fungus
    • Bozza, S., R. Gaziano, A. Spreca, A. Bacci, C. Montagnoli, P. di Francesco, and L. Romani. 2002. Dendritic cells transport conidia and hyphae of Aspergillus fumigatus from the airways to the draining lymph nodes and initiate disparate Th responses to the fungus. J. Immunol. 168: 1362-1371.
    • (2002) J. Immunol. , vol.168 , pp. 1362-1371
    • Bozza, S.1    Gaziano, R.2    Spreca, A.3    Bacci, A.4    Montagnoli, C.5    Di Francesco, P.6    Romani, L.7
  • 13
    • 27744503985 scopus 로고    scopus 로고
    • Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis
    • Carpenter, K. J., and C. M. Hogaboam. 2005. Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis. Infect. Immun. 73: 7198-7207.
    • (2005) Infect. Immun. , vol.73 , pp. 7198-7207
    • Carpenter, K.J.1    Hogaboam, C.M.2
  • 15
    • 34249805431 scopus 로고    scopus 로고
    • The role of CC chemokine receptor 6 in host defense in a model of invasive pulmonary aspergillosis
    • Phadke, A. P., G. Akangire, S. J. Park, S. A. Lira, and B. Mehrad. 2007. The role of CC chemokine receptor 6 in host defense in a model of invasive pulmonary aspergillosis. Am. J. Respir. Crit. Care Med. 175: 1165-1172.
    • (2007) Am. J. Respir. Crit. Care Med. , vol.175 , pp. 1165-1172
    • Phadke, A.P.1    Akangire, G.2    Park, S.J.3    Lira, S.A.4    Mehrad, B.5
  • 18
    • 33644757642 scopus 로고    scopus 로고
    • Human dendritic cells following Aspergillus fumigatus infection express the CCR7 receptor and a differential pattern of interleukin-12 (IL-12), IL-23, and IL-27 cytokines, which lead to a Th1 response
    • Gafa, V., R. Lande, M. C. Gagliardi, M. Severa, E. Giacomini, M. E. Remoli, R. Nisini, C. Ramoni, P. Di Francesco, D. Aldebert, et al. 2006. Human dendritic cells following Aspergillus fumigatus infection express the CCR7 receptor and a differential pattern of interleukin-12 (IL-12), IL-23, and IL-27 cytokines, which lead to a Th1 response. Infect. Immun. 74: 1480-1489.
    • (2006) Infect. Immun. , vol.74 , pp. 1480-1489
    • Gafa, V.1    Lande, R.2    Gagliardi, M.C.3    Severa, M.4    Giacomini, E.5    Remoli, M.E.6    Nisini, R.7    Ramoni, C.8    Di Francesco, P.9    Aldebert, D.10
  • 19
    • 34250677730 scopus 로고    scopus 로고
    • In vitro infection of human dendritic cells by Aspergillus fumigatus conidia triggers the secretion of chemokines for neutrophil and Th1 lymphocyte recruitment
    • Gafa, V., M. E. Remoli, E. Giacomini, M. C. Gagliardi, R. Lande, M. Severa, R. Grillot, and E. M. Coccia. 2007. In vitro infection of human dendritic cells by Aspergillus fumigatus conidia triggers the secretion of chemokines for neutrophil and Th1 lymphocyte recruitment. Microbes Infect. 9: 971-980.
    • (2007) Microbes Infect. , vol.9 , pp. 971-980
    • Gafa, V.1    Remoli, M.E.2    Giacomini, E.3    Gagliardi, M.C.4    Lande, R.5    Severa, M.6    Grillot, R.7    Coccia, E.M.8
  • 20
    • 0033105359 scopus 로고    scopus 로고
    • Cutting edge: Secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes
    • Saeki, H., A. M. Moore, M. J. Brown, and S. T. Hwang. 1999. Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes. J. Immunol. 162: 2472-2475. (Pubitemid 29309263)
    • (1999) Journal of Immunology , vol.162 , Issue.5 , pp. 2472-2475
    • Saeki, H.1    Moore, A.M.2    Brown, M.J.3    Hwang, S.T.4
  • 21
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto, F., D. Lenig, R. Forster, M. Lipp, and A. Lanzavecchia. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401: 708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 23
    • 0031892090 scopus 로고    scopus 로고
    • A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes
    • Gunn, M. D., K. Tangemann, C. Tam, J. G. Cyster, S. D. Rosen, and L. T. Williams. 1998. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc. Natl. Acad. Sci. USA 95: 258-263.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 258-263
    • Gunn, M.D.1    Tangemann, K.2    Tam, C.3    Cyster, J.G.4    Rosen, S.D.5    Williams, L.T.6
  • 24
    • 23444451916 scopus 로고    scopus 로고
    • Dendritic-cell trafficking to lymph nodes through lymphatic vessels
    • Randolph, G. J., V. Angeli, and M. A. Swartz. 2005. Dendritic-cell trafficking to lymph nodes through lymphatic vessels. Nat. Rev. Immunol. 5: 617-628.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 617-628
    • Randolph, G.J.1    Angeli, V.2    Swartz, M.A.3
  • 25
    • 42649086026 scopus 로고    scopus 로고
    • CCR7 and its ligands: Balancing immunity and tolerance
    • Forster, R., A. C. Davalos-Misslitz, and A. Rot. 2008. CCR7 and its ligands: balancing immunity and tolerance. Nat. Rev. Immunol. 8: 362-371.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 362-371
    • Forster, R.1    Davalos-Misslitz, A.C.2    Rot, A.3
  • 26
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 27
    • 0033214348 scopus 로고    scopus 로고
    • CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
    • Forster, R., A. Schubel, D. Breitfeld, E. Kremmer, I. Renner-Muller, E. Wolf, and M. Lipp. 1999. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99: 23-33.
    • (1999) Cell , vol.99 , pp. 23-33
    • Forster, R.1    Schubel, A.2    Breitfeld, D.3    Kremmer, E.4    Renner-Muller, I.5    Wolf, E.6    Lipp, M.7
  • 28
    • 0033485741 scopus 로고    scopus 로고
    • CXC chemokine receptor-2 ligands are necessary components of neutrophil-mediated host defense in invasive pulmonary aspergillosis
    • Mehrad, B., R. M. Strieter, T. A. Moore, W. C. Tsai, S. A. Lira, and T. J. Standiford. 1999. CXC chemokine receptor-2 ligands are necessary components of neutrophil-mediated host defense in invasive pulmonary aspergillosis. J. Immunol. 163: 6086-6094.
    • (1999) J. Immunol. , vol.163 , pp. 6086-6094
    • Mehrad, B.1    Strieter, R.M.2    Moore, T.A.3    Tsai, W.C.4    Lira, S.A.5    Standiford, T.J.6
  • 29
    • 0036467429 scopus 로고    scopus 로고
    • Ectopic expression of the murine chemokines CCL21a and CCL21b induces the formation of lymph nodelike structures in pancreas, but not skin, of transgenic mice
    • Chen, S. C., G. Vassileva, D. Kinsley, S. Holzmann, D. Manfra, M. T. Wiekowski, N. Romani, and S. A. Lira. 2002. Ectopic expression of the murine chemokines CCL21a and CCL21b induces the formation of lymph nodelike structures in pancreas, but not skin, of transgenic mice. J. Immunol. 168: 1001-1008.
    • (2002) J. Immunol. , vol.168 , pp. 1001-1008
    • Chen, S.C.1    Vassileva, G.2    Kinsley, D.3    Holzmann, S.4    Manfra, D.5    Wiekowski, M.T.6    Romani, N.7    Lira, S.A.8
  • 30
    • 5444269747 scopus 로고    scopus 로고
    • Accurate and simple discrimination of mouse pulmonary dendritic cell and macrophage populations by flow cytometry: Methodology and new insights
    • Vermaelen, K., and R. Pauwels. 2004. Accurate and simple discrimination of mouse pulmonary dendritic cell and macrophage populations by flow cytometry: methodology and new insights. Cytometry A 61: 170-177.
    • (2004) Cytometry A , vol.61 , pp. 170-177
    • Vermaelen, K.1    Pauwels, R.2
  • 31
    • 38349143708 scopus 로고    scopus 로고
    • Polymorphisms in the chemokine (C-X-C motif) ligand 10 are associated with invasive aspergillosis after allogeneic stem-cell transplantation and influence CXCL10 expression in monocyte-derived dendritic cells
    • Mezger, M., M. Steffens, M. Beyer, C. Manger, J. Eberle, M. R. Toliat, T. F. Wienker, P. Ljungman, H. Hebart, H. J. Dornbusch, H. Einsele, and J. Loeffler. 2008. Polymorphisms in the chemokine (C-X-C motif) ligand 10 are associated with invasive aspergillosis after allogeneic stem-cell transplantation and influence CXCL10 expression in monocyte-derived dendritic cells. Blood 111: 534-536.
    • (2008) Blood , vol.111 , pp. 534-536
    • Mezger, M.1    Steffens, M.2    Beyer, M.3    Manger, C.4    Eberle, J.5    Toliat, M.R.6    Wienker, T.F.7    Ljungman, P.8    Hebart, H.9    Dornbusch, H.J.10    Einsele, H.11    Loeffler, J.12
  • 35
    • 0037131427 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus
    • Mambula, S. S., K. Sau, P. Henneke, D. T. Golenbock, and S. M. Levitz. 2002. Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus. J. Biol. Chem. 277: 39320-39326.
    • (2002) J. Biol. Chem. , vol.277 , pp. 39320-39326
    • Mambula, S.S.1    Sau, K.2    Henneke, P.3    Golenbock, D.T.4    Levitz, S.M.5
  • 36
    • 0043198157 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) 2 and TLR4 are essential for Aspergillus-induced activation of murine macrophages
    • Meier, A., C. J. Kirschning, T. Nikolaus, H. Wagner, J. Heesemann, and F. Ebel. 2003. Toll-like receptor (TLR) 2 and TLR4 are essential for Aspergillus-induced activation of murine macrophages. Cell. Microbiol. 5: 561-570.
    • (2003) Cell. Microbiol. , vol.5 , pp. 561-570
    • Meier, A.1    Kirschning, C.J.2    Nikolaus, T.3    Wagner, H.4    Heesemann, J.5    Ebel, F.6
  • 39
    • 22844448173 scopus 로고    scopus 로고
    • Incidence of invasive aspergillosis following hematopoietic stem cell and solid organ transplantation: Interim results of a prospective multicenter surveillance program
    • Morgan, J., K. A. Wannemuehler, K. A. Marr, S. Hadley, D. P. Kontoyiannis, T. J. Walsh, S. K. Fridkin, P. G. Pappas, and D. W. Warnock. 2005. Incidence of invasive aspergillosis following hematopoietic stem cell and solid organ transplantation: interim results of a prospective multicenter surveillance program. Med. Mycol. 43(Suppl. 1): S49-S58.
    • (2005) Med. Mycol. , vol.43 , Issue.SUPPL. 1
    • Morgan, J.1    Wannemuehler, K.A.2    Marr, K.A.3    Hadley, S.4    Kontoyiannis, D.P.5    Walsh, T.J.6    Fridkin, S.K.7    Pappas, P.G.8    Warnock, D.W.9
  • 40
    • 0031871318 scopus 로고    scopus 로고
    • Pulmonary aspergillosis and invasive disease in AIDS: Review of 342 cases
    • Mylonakis, E., T. F. Barlam, T. Flanigan, and J. D. Rich. 1998. Pulmonary aspergillosis and invasive disease in AIDS: review of 342 cases. Chest 114: 251-262. (Pubitemid 28337391)
    • (1998) Chest , vol.114 , Issue.1 , pp. 251-262
    • Mylonakis, E.1    Barlam, T.F.2    Flanigan, T.3    Rich, J.D.4
  • 42
    • 23244454436 scopus 로고    scopus 로고
    • CCR2 and CCR6, but not endothelial selectins, mediate the accumulation of immature dendritic cells within the lungs of mice in response to particulate antigen
    • Osterholzer, J. J., T. Ames, T. Polak, J. Sonstein, B. B. Moore, S. W. Chensue, G. B. Toews, and J. L. Curtis. 2005. CCR2 and CCR6, but not endothelial selectins, mediate the accumulation of immature dendritic cells within the lungs of mice in response to particulate antigen. J. Immunol. 175: 874-883.
    • (2005) J. Immunol. , vol.175 , pp. 874-883
    • Osterholzer, J.J.1    Ames, T.2    Polak, T.3    Sonstein, J.4    Moore, B.B.5    Chensue, S.W.6    Toews, G.B.7    Curtis, J.L.8
  • 44
    • 0033084013 scopus 로고    scopus 로고
    • Role of TNF-α in pulmonary host defense in murine invasive aspergillosis
    • Mehrad, B., R. M. Strieter, and T. J. Standiford. 1999. Role of TNF-α in pulmonary host defense in murine invasive aspergillosis. J. Immunol. 162: 1633-1640. (Pubitemid 29307039)
    • (1999) Journal of Immunology , vol.162 , Issue.3 , pp. 1633-1640
    • Mehrad, B.1    Strieter, R.M.2    Standiford, T.J.3
  • 45
    • 0026048714 scopus 로고
    • The pathogenesis of sepsis
    • Bone, R. C. 1991. The pathogenesis of sepsis. Ann. Intern. Med. 115: 457-469.
    • (1991) Ann. Intern. Med. , vol.115 , pp. 457-469
    • Bone, R.C.1
  • 47
    • 0028973391 scopus 로고
    • Interferon-gamma and tumor necrosis factor-alpha protect mice from invasive aspergillosis
    • Nagai, H., J. Guo, H. Choi, and V. Kurup. 1995. Interferon-γ and tumor necrosis factor-alpha protect mice from invasive aspergillosis. J. Infect. Dis. 172: 1554-1560. (Pubitemid 3023470)
    • (1995) Journal of Infectious Diseases , vol.172 , Issue.6 , pp. 1554-1560
    • Nagai, H.1    Guo, J.2    Choi, H.3    Kurup, V.4


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