A Tris (2-Carboxyethyl) Phosphine (TCEP) Related Cleavage on Cysteine-Containing Proteins

Journal of the American Society for Mass Spectrometry

Volumn 21, Issue 5, 2010, Pages 837-844

  Liu, Peiran ^a   O'Mara, Brian W ^a   Warrack, Bethanne M ^a   Wu, Wei ^a   Huang, Yunping ^a   Zhang, Yihong ^b   Zhao, Rulin ^a   Lin, Mei ^a   Ackerman, Michael S ^a   Hocknell, Peter K ^b   Chen, Guodong ^a   Tao, Li ^a   Rieble, Siegfried ^a   Wang, Jack ^b   Wang Iverson, David B ^a   Tymiak, Adrienne A ^a   Grace, Michael J ^a   Russell, Reb J ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b A Bristol Myers Squibb R and D Company   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINUS; CARBON-CARBON BOND; CYSTEINE RESIDUES; LC/MS/MS; PEPTIDE PRODUCTS; PRIMARY AMINES; PROTEIN BACKBONE; REDUCING REAGENTS; REDUCTANTS; SIDE REACTIONS; TANDEM MASS SPECTROMETRY; TRIS(2-CARBOXYETHYL) PHOSPHINE;

CARBOXYLIC ACIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ORGANIC ACIDS; PHOSPHORUS COMPOUNDS;

PEPTIDES;

AMINE; CARBOXYLIC ACID; CYSTEINE; GLYOXYLIC ACID; TRIS(2 CARBOXYETHYL)PHOSPHINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PH; PROTEIN BINDING; PROTEIN CLEAVAGE; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; HYDROGEN-ION CONCENTRATION; PEPTIDE FRAGMENTS; PHOSPHINES; PROTEINS; TANDEM MASS SPECTROMETRY;

EID: 77951208747     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2010.01.016     Document Type: Article

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