Low sensitivity in clinical diagnoses of dementia with Lewy bodies

Journal of Neurology

Volumn 257, Issue 3, 2010, Pages 359-366

  Nelson, Peter T ^a,b   Jicha, Gregory A ^b   Kryscio, Richard J ^a,b   Abner, Erin L ^b   Schmitt, Frederick A ^b   Cooper, Gregory ^b   Xu, Li O ^a   Smith, Charles D ^b   Markesbery, William R ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; AUTOPSY; CLINICAL EVALUATION; CLINICAL FEATURE; COGNITIVE DEFECT; CONTROLLED STUDY; DEGENERATIVE DISEASE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFUSE LEWY BODY DISEASE; EXTRAPYRAMIDAL SYMPTOM; HUMAN; INTERMETHOD COMPARISON; NEUROPATHOLOGY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; VISUAL HALLUCINATION;

AGED; BRAIN; COGNITION DISORDERS; DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC ERRORS; HALLUCINATIONS; HUMANS; LEWY BODIES; LEWY BODY DISEASE; MUSCLE RIGIDITY; PREDICTIVE VALUE OF TESTS; REGISTRIES;

EID: 77951205622     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-009-5324-y     Document Type: Article

References (37)

1. (1997) Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease. Neurobiol Aging 18:S1-2 (Pubitemid 27454689)
2. DL Beekly EM Ramos WW Lee WD Deitrich ME Jacka J Wu JL Hubbard TD Koepsell JC Morris WA Kukull 2007 The National Alzheimer's Coordinating Center (NACC) database: the uniform data set Alzheimer Dis Assoc Disord 21 249 258 10.1097/WAD.0b013e318142774e 17804958 (Pubitemid 47367978)
3. DL Beekly EM Ramos G van Belle W Deitrich AD Clark ME Jacka WA Kukull 2004 The National Alzheimer's Coordinating Center (NACC) database: an Alzheimer disease database Alzheimer Dis Assoc Disord 18 270 277 15592144 (Pubitemid 40076162)
4. JV Bowler DG Munoz H Merskey V Hachinski 1998 Fallacies in the pathological confirmation of the diagnosis of Alzheimer's disease J Neurol Neurosurg Psychiatry 64 18 24 10.1136/jnnp.64.1.18 1:STN:280: DyaK1c%2FpslahsA%3D%3D 9436722 (Pubitemid 28156532)
5. H Braak E Braak J Bohl 1993 Staging of Alzheimer-related cortical destruction Eur Neurol 33 403 408 10.1159/000116984 1:STN:280: DyaK2c7jvFOrsg%3D%3D 8307060
6. S Engelborghs K Maertens G Nagels E Vloeberghs P Marien A Symons V Ketels S Estercam N Somers PP De Deyn 2005 Neuropsychiatric symptoms of dementia: cross-sectional analysis from a prospective, longitudinal Belgian study Int J Geriatr Psychiatry 20 1028 1037 10.1002/gps.1395 16250064 (Pubitemid 41723573)
7. MS Fernando PG Ince 2004 Vascular pathologies and cognition in a population-based cohort of elderly people J Neurol Sci 226 13 17 10.1016/j.jns.2004.09.004 15537512 (Pubitemid 39505399)
8. R Holtzer MX Tang DP Devanand SM Albert DJ Wegesin K Marder K Bell M Albert J Brandt Y Stern 2003 Psychopathological features in Alzheimer's disease: course and relationship with cognitive status J Am Geriatr Soc 51 953 960 10.1046/j.1365-2389.2003.51308.x 12834515 (Pubitemid 36871143)
9. KA Jellinger 2008 A critical evaluation of current staging of alpha-synuclein pathology in Lewy body disorders Biochim Biophys Acta 1792 730 740 18718530
10. KA Jellinger 2004 Lewy body-related alpha-synucleinopathy in the aged human brain J Neural Transm 111 1219 1235 10.1007/s00702-004-0138-7 1:CAS:528:DC%2BD2cXotFCrtbk%3D 15480835 (Pubitemid 39468387)
11. KA Jellinger J Attems 2008 Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease Acta Neuropathol 115 427 436 10.1007/s00401-008-0347-5 18273624
12. Jicha GA, Schmitt FA, Abner E, Nelson PT, Cooper GE, Smith CD, Markesbery WR (2008) Prodromal clinical manifestations of neuropathologically confirmed Lewy body disease. Neurobiol Aging
13. ML Kraybill EB Larson DW Tsuang L Teri WC McCormick JD Bowen WA Kukull JB Leverenz MM Cherrier 2005 Cognitive differences in dementia patients with autopsy-verified AD, Lewy body pathology, or both Neurology 64 2069 2073 10.1212/01.WNL.0000165987.89198.65 1:STN:280:DC%2BD2MzjsFSguw%3D%3D 15985574 (Pubitemid 40880995)
14. OL Lopez RL Hamilton JT Becker S Wisniewski DI Kaufer ST DeKosky 2000 Severity of cognitive impairment and the clinical diagnosis of AD with Lewy bodies Neurology 54 1780 1787 1:STN:280:DC%2BD3c3msVCmsg%3D%3D 10802784
15. CA Luis WW Barker K Gajaraj D Harwood R Petersen A Kashuba C Waters P Jimison G Pearl C Petito D Dickson R Duara 1999 Sensitivity and specificity of three clinical criteria for dementia with Lewy bodies in an autopsy-verified sample Int J Geriatr Psychiatry 14 526 533 10.1002/(SICI)1099-1166(199907)14: 7<526::AID-GPS965>3.0.CO;2-0 1:STN:280:DyaK1MzntVaquw%3D%3D 10440972 (Pubitemid 29366637)
16. I McKeith J Mintzer D Aarsland D Burn H Chiu J Cohen-Mansfield D Dickson B Dubois JE Duda H Feldman S Gauthier G Halliday B Lawlor C Lippa OL Lopez J Carlos Machado J O'Brien J Playfer W Reid 2004 Dementia with Lewy bodies Lancet Neurol 3 19 28 10.1016/S1474-4422(03)00619-7 14693108 (Pubitemid 38018924)
17. IG McKeith DW Dickson J Lowe M Emre JT O'Brien H Feldman J Cummings JE Duda C Lippa EK Perry D Aarsland H Arai CG Ballard B Boeve DJ Burn D Costa T Del Ser B Dubois D Galasko S Gauthier CG Goetz E Gomez-Tortosa G Halliday LA Hansen J Hardy T Iwatsubo RN Kalaria D Kaufer RA Kenny A Korczyn K Kosaka VM Lee A Lees I Litvan E Londos OL Lopez S Minoshima Y Mizuno JA Molina EB Mukaetova-Ladinska F Pasquier RH Perry JB Schulz JQ Trojanowski M Yamada 2005 Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium Neurology 65 1863 1872 10.1212/01.wnl.0000187889.17253.b1 1:STN:280:DC%2BD2Mnpt1GqsQ%3D%3D 16237129 (Pubitemid 43970103)
18. IG McKeith D Galasko K Kosaka EK Perry DW Dickson LA Hansen DP Salmon J Lowe SS Mirra EJ Byrne G Lennox NP Quinn JA Edwardson PG Ince C Bergeron A Burns BL Miller S Lovestone D Collerton EN Jansen C Ballard RA de Vos GK Wilcock KA Jellinger RH Perry 1996 Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop Neurology 47 1113 1124 1:STN:280:DyaK2s%2FmsF2gtw%3D%3D 8909416
19. AR Merdes LA Hansen DV Jeste D Galasko CR Hofstetter GJ Ho LJ Thal J Corey-Bloom 2003 Influence of Alzheimer pathology on clinical diagnostic accuracy in dementia with Lewy bodies Neurology 60 1586 1590 1:STN:280:DC%2BD3s3kvVWqsw%3D%3D 12771246
20. SS Mirra 1997 The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer's disease: a commentary Neurobiol Aging 18 S91 S94 10.1016/S0197-4580(97)00058-4 1:STN:280:DyaK2svnt1Sksw%3D%3D 9330994 (Pubitemid 27454705)
21. W Mok TW Chow L Zheng WJ Mack C Miller 2004 Clinicopathological concordance of dementia diagnoses by community versus tertiary care clinicians Am J Alzheimer's Dis Other Demen 19 161 165 10.1177/153331750401900309 1:STN:280:DC%2BD2czht12ntQ%3D%3D
22. Nelson PT, Abner EL, Schmitt FA, Kryscio RJ, Jicha GA, Smith CD, Davis D, Poduska JW, Patel E, Mendiondo MM, Markesbery WR (2008) Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons. Brain Pathol (in press)
23. PT Nelson H Braak WR Markesbery 2009 Neuropathology and cognitive impairment in Alzheimer disease: a complex but coherent relationship J Neuropathol Exp Neuro 68 1 14 10.1097/NEN.0b013e3181919a48 1:CAS:528: DC%2BD1MXhsFGlsrw%3D
24. PT Nelson GA Jicha FA Schmitt H Liu DG Davis MS Mendiondo EL Abner WR Markesbery 2007 Clinicopathologic correlations in a large Alzheimer disease center autopsy cohort: neuritic plaques and neurofibrillary tangles "do count" when staging disease severity J Neuropathol Exp Neurol 66 1136 1146 10.1097/nen.0b013e31815c5efb 18090922 (Pubitemid 350294663)
25. PT Nelson RJ Kryscio EL Abner FA Schmitt GA Jicha MS Mendiondo G Cooper CB Smith WR Markesbery 2009 Acetylcholinesterase inhibitor treatment is associated with relatively slow cognitive decline in patients with Alzheimer's disease and AD + DLB J Alzheimers Dis 16 29 34 1:CAS:528:DC%2BD1MXjt1Siu7c%3D 19158418
26. JM Olichney D Galasko DP Salmon CR Hofstetter LA Hansen R Katzman LJ Thal 1998 Cognitive decline is faster in Lewy body variant than in Alzheimer's disease Neurology 51 351 357 1:STN:280:DyaK1czntlOktA%3D%3D 9710002 (Pubitemid 28406305)
27. L Parkkinen T Kauppinen T Pirttila JM Autere I Alafuzoff 2005 Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia Ann Neurol 57 82 91 10.1002/ana.20321 1:CAS:528:DC%2BD2MXpsFSktQ%3D%3D 15562510 (Pubitemid 40053318)
28. L Parkkinen T Pirttila I Alafuzoff 2008 Applicability of current staging/categorization of alpha-synuclein pathology and their clinical relevance Acta Neuropathol 115 399 407 10.1007/s00401-008-0346-6 18297293
29. L Parkkinen T Pirttila M Tervahauta I Alafuzoff 2005 Widespread and abundant alpha-synuclein pathology in a neurologically unimpaired subject Neuropathology 25 304 314 10.1111/j.1440-1789.2005.00644.x 16382779 (Pubitemid 43943239)
30. L Parkkinen H Soininen I Alafuzoff 2003 Regional distribution of alpha-synuclein pathology in unimpaired aging and Alzheimer disease J Neuropathol Exp Neurol 62 363 367 1:CAS:528:DC%2BD3sXjt1yrsbk%3D 12722828
31. L Parkkinen H Soininen M Laakso I Alafuzoff 2001 Alpha-synuclein pathology is highly dependent on the case selection Neuropathol Appl Neurobiol 27 314 325 10.1046/j.0305-1846.2001.00342.x 1:STN:280:DC%2BD3MvovFehuw%3D%3D 11532162 (Pubitemid 32758618)
32. GS Pearl 1997 Diagnosis of Alzheimer's disease in a community hospital-based brain bank program South Med J 90 720 722 10.1097/00007611- 199707000-00013 1:STN:280:DyaK2szmvFCjtQ%3D%3D 9225895 (Pubitemid 27304711)
33. CK Rosenberg MA Pericak-Vance AM Saunders JR Gilbert PC Gaskell CM Hulette 2000 Lewy body and Alzheimer pathology in a family with the amyloid-beta precursor protein APP717 gene mutation Acta Neuropathol 100 145 152 10.1007/s004019900155 1:CAS:528:DC%2BD3cXmtFKisLg%3D 10963361
34. JA Schneider RS Wilson JL Bienias DA Evans DA Bennett 2004 Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology Neurology 62 1148 1155 1:STN:280:DC%2BD2c7otlGnuw%3D%3D 15079015
35. K Stavitsky AM Brickman N Scarmeas RL Torgan MX Tang M Albert J Brandt D Blacker Y Stern 2006 The progression of cognition, psychiatric symptoms, and functional abilities in dementia with Lewy bodies and Alzheimer disease Arch Neurol 63 1450 1456 10.1001/archneur.63.10.1450 17030662 (Pubitemid 44547558)
36. Y Trembath C Rosenberg JF Ervin DE Schmechel P Gaskell M Pericak-Vance J Vance CM Hulette 2003 Lewy body pathology is a frequent co-pathology in familial Alzheimer's disease Acta Neuropathol 105 484 488 12677449
37. D Tsuang K Simpson EB Larson E Peskind W Kukull JB Bowen W McCormick L Teri T Montine ML Thompson JB Leverenz 2006 Predicting Lewy body pathology in a community-based sample with clinical diagnosis of Alzheimer's disease J Geriatr Psychiatry Neurol 19 195 201 10.1177/0891988706292755 17085757 (Pubitemid 44664178)