Wake promoting effects of cocaine and amphetamine-regulated transcript (CART)

Neuropeptides

Volumn 44, Issue 3, 2010, Pages 241-246

  Keating, G L ^a   Kuhar, Michael J ^b   Bliwise, Donald L ^a   Rye, David B ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

Hypocretin; Hypothalamus; Rebound; Sleep

Indexed keywords

COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE 55-102; UNCLASSIFIED DRUG;

ALERTNESS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ACTIVITY; DRUG MECHANISM; ENZYME INACTIVATION; ENZYME REGULATION; HYPOTHALAMUS; LIGHT DARK CYCLE; MALE; MOUSE; NONHUMAN; NONREM SLEEP; PRIORITY JOURNAL; PROTEIN FUNCTION; REBOUND; REM SLEEP; SLEEP WAKING CYCLE; WAKEFULNESS;

ANIMALS; HYPOTHALAMUS; MALE; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; SLEEP; WAKEFULNESS;

RATTUS;

EID: 77951204655     PISSN: 01434179     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.npep.2009.12.013     Document Type: Article

References (33)

1. Adamantidis A., de Lecea L. Sleep and metabolism: shared circuits, new connections. Trends Endocrinol. Metab. 2008, 19:362-370.
2. Broberger C., Holmberg K., Kuhar M.J., Hokfelt T. Cocaine- and amphetamine-regulated transcript in the rat vagus nerve: a putative mediator of cholecystokinin-induced satiety. Proc. Natl. Acad. Sci. USA 1999, 96:13506-13511.
3. Buckley T.M., Schatzberg A.F. On the interactions of the hypothalamic-pituitary-adrenal (HPA) axis and sleep: normal HPA axis activity and circadian rhythm, exemplary sleep disorders. J. Clin. Endocrinol. Metab. 2005, 90:3106-3114.
4. Dallvechia-Adams S., Kuhar M.J., Smith Y. Cocaine- and amphetamine-regulated transcript peptide projections in the ventral midbrain: colocalization with gamma-aminobutyric acid, melanin-concentrating hormone, dynorphin, and synaptic interactions with dopamine neurons. J. Comp. Neurol. 2002, 448:360-372.
5. Davidowa H., Li Y., Plagemann A. Altered responses to orexigenic (AGRP, MCH) and anorexigenic (alpha-MSH, CART) neuropeptides of paraventricular hypothalamic neurons in early postnatally overfed rats. Eur. J. Neurosci. 2003, 18:613-621.
6. Douglass J., McKinzie A.A., Couceyro P. PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine. J. Neurosci. 1995, 15:2471-2481.
7. Edgar D.M., Seidel W.F. Modafinil induces wakefulness without intensifying motor activity or subsequent rebound hypersomnolence in the rat. J. Pharmacol. Exp. Ther. 1997, 283:757-769.
8. Elias C.F., Lee C.E., Kelly J.F., Ahima R.S., Kuhar M., Saper C.B., Elmquist J.K. Characterization of CART neurons in the rat and human hypothalamus. J. Comp. Neurol. 2001, 432:1-19.
9. Fort P., Bassetti C.L., Luppi P.H. Alternating vigilance states: new insights regarding neuronal networks and mechanisms. Eur. J. Neurosci. 2009, 29:1741-1753.
10. Hagan J.J., Leslie R.A., Patel S., Evans M.L., Wattam T.A., Holmes S., Benham C.D., Taylor S.G., Routledge C., Hemmati P., Munton R.P., Ashmeade T.E., Shah A.S., Hatcher J.P., Hatcher P.D., Jones D.N., Smith M.I., Piper D.C., Hunter A.J., Porter R.A., Upton N. Orexin A activates locus coeruleus cell firing and increases arousal in the rat. Proc. Natl. Acad. Sci. USA 1999, 96:10911-10916.
11. Hanriot L., Camargo N., Courau A.C., Leger L., Luppi P.H., Peyron C. Characterization of the melanin-concentrating hormone neurons activated during paradoxical sleep hypersomnia in rats. J. Comp. Neurol. 2007, 505:147-157.
12. Keating G.L., Kuhar M.J., Rye D.B. High dose CART peptide induces abnormal EEG activity and behavioral seizures. Neuropeptides 2008, 42:199-204.
13. Kirouac G.J., Parsons M.P., Li S. Innervation of the paraventricular nucleus of the thalamus from cocaine- and amphetamine-regulated transcript (CART) containing neurons of the hypothalamus. J. Comp. Neurol. 2006, 497:155-165.
14. Koylu E.O., Couceyro P.R., Lambert P.D., Kuhar M.J. Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain. J. Comp. Neurol. 1998, 391:115-132.
15. Koylu E., Smith Y., Couceyro P., Kuhar M. CART peptides colocalize with tyrosine hydroxylase in rat locus coeruleus. Synapse 1999, 31:309-311.
16. Kuhar M.J., Adams L.D., Hunter R.G., Vechia S.D., Smith Y. CART peptides. Regul. Pept. 2000, 89:1-6.
17. Mignot E., Taheri S., Nishino S. Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders. Nature Neurosci. 2002, 5(Suppl.):1071-1075.
18. Minzenberg M.J., Carter C.S. Modafinil: a review of neurochemical actions and effects on cognition. Neuropsychopharmacology 2008, 33:1477-1502.
19. Murphy K.G., Abbott C.R., Mahmoudi M., Hunter R., Gardiner J.V., Rossi M., Stanley S.A., Ghatei M.A., Kuhar M.J., Bloom S.R. Quantification and synthesis of cocaine- and amphetamine-regulated transcript peptide (79-102)-like immunoreactivity and mRNA in rat tissues. J. Endocrinol. 2000, 166:659-668.
20. Nishino S. The hypothalamic peptidegeric system, hypocetin/orexin and vigilance control. Neuropeptides 2007, 41:117-133.
21. Peyron C. Molecular characterization of hypocretin/orexin and MCH neurons: relevance to narcolepsy. Narcolepsy and Hypersomnia 2006, Marcel Dekker Inc., New York. C. Basetti, M. Billard, E. Mignot (Eds.).
22. Piper D.C., Upton N., Smith M.I., Hunter A.J. The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats. Eur. J. Neurosci. 2000, 12:726-730.
23. Rogge G., Jones D., Hubert W., Lin Y., Kuahr M.J. CART peptides: regulators of body weight, reward and other functions. Nature Rev.: Neurosci. 2008, 9:747-758.
24. Rye D. The two faces of Eve: dopamine's modulation of wakefulness and sleep. Neurology 2004, 63(Suppl. 3):S2-S7.
25. Scammell T. The neurobiology, diagnosis, and treatment of narcolepsy. Ann. Neurol. 2003, 53:154-166.
26. Shieh K.R., Yang S.C. Effects of estradiol on the stimulation of dopamine turnover in mesolimbic and nigrostriatal systems by cocaine- and amphetamine-regulated transcript peptide in female rats. Neuroscience 2008, 154:1589-1597.
27. Smith Y., Kieval J., Couceyro P.R., Kuhar M.J. CART peptide-immunoreactive neurones in the nucleus accumbens in monkeys: ultrastructural analysis, colocalization studies, and synaptic interactions with dopaminergic afferents. J. Comp. Neurol. 1999, 407:491-511.
28. Smith S.M., Vaughan J.M., Donaldson C.J., Rivier J., Li C., Chen A., Vale W.W. Cocaine- and amphetamine-regulated transcript activates the hypothalamic-pituitary-adrenal axis through a corticotropin-releasing factor receptor-dependent mechanism. Endocrinology 2004, 145:5202-5209.
29. Stanek L.M. Cocaine- and amphetamine related transcript (CART) and anxiety. Peptides 2006, 27:2005-2011.
30. Vicentic A. CART peptide diurnal variations in blood and brain. Peptides 2006, 27:1942-1948.
31. Vicentic A., Lakatos A., Jones D. The CART receptors: background and recent advances. Peptides 2006, 27:1934-1937.
32. Wisor J., Nishino S., Sora I., Uhl G., Mignot E., Edgar D. Dopaminergic role in stimulant-induced wakefulness. J. Neurosci. 2001, 21:1787-1794.
33. Yang S.C., Pan J.T., Li H.Y. CART peptide increaces the mesolimbic dopaminergic neuronal activity: a microdialysis study. Eur. J. Pharmacol. 2004, 494:179-182.