Major role of epidermal growth factor receptor and Src kinases in promoting oxidative stress-dependent loss of adhesion and apoptosis in epithelial cells

Journal of Biological Chemistry

Volumn 285, Issue 7, 2010, Pages 4307-4318

  Chan, Hong Lin ^a,b   Chou, Hsiu Chuan ^c,d   Duran, MaCarmen ^a   Gruenewald, Jana ^c   Waterfield, Michael D ^e   Ridley, Anne ^c   Timms, John F ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE   (Taiwan)

^e LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN CYTOSKELETON; APOPTOSIS; CELL DAMAGE; CELL SIGNALING; CELL SYSTEM; CELL-CELL JUNCTIONS; CELLULAR CHANGES; CRITICAL COMPONENT; EPIDERMAL GROWTH FACTOR RECEPTORS; EPITHELIAL CELLS; GENERAL MODEL; HUMAN EPITHELIAL CELLS; HYDROGEN PEROXIDE TREATMENT; IN-CELL; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MORPHOLOGICAL CHANGES; OXIDATIVE DAMAGE; OXIDATIVE STRESS-DEPENDENT; PHOSPHORYLATED PROTEINS; PHOSPHOTYROSINE; PROTEIN PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; REDOX ACTIVATION; REDOX SIGNALING; SRC-KINASE; STRESS-INDUCED; TYROSINE PHOSPHORYLATION;

AMINO ACIDS; BIOACTIVITY; CELL ADHESION; CELL DEATH; CELL MEMBRANES; HYDROGEN PEROXIDE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATIVE STRESS; OXYGEN; PEPTIDES; PHOSPHATASES; PHOSPHORYLATION; PRESSURE EFFECTS; SIGNALING;

ADHESION;

ACTIN; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN DERIVATIVE; PROTEIN TYROSINE KINASE; TYROSINE;

APOPTOSIS; ARTICLE; CELL ADHESION; CELL DAMAGE; CELL JUNCTION; CELL STRESS; CELL STRUCTURE; CYTOSKELETON; ENZYME ACTIVITY; EPITHELIUM CELL; HUMAN; HUMAN CELL; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL ADHESION; CELL LINE; CELL SURVIVAL; CHROMATOGRAPHY, LIQUID; EPITHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICROSCOPY, CONFOCAL; OXIDATIVE STRESS; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; TANDEM MASS SPECTROMETRY;

EID: 77951189195     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.047027     Document Type: Article

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