Recurrent neonatal seizures result in long-term increases in neuronal network excitability in the rat neocortex

European Journal of Neuroscience

Volumn 31, Issue 8, 2010, Pages 1446-1455

  Isaeva, Elena ^a,b   Isaev, Dmytro ^a,b   Savrasova, Alina ^b   Khazipov, Rustem ^c   Holmes, Gregory L ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b BOGOMOLETZ INSTITUTE OF PHYSIOLOGY   (Ukraine)

^c Turing Center for Living Systems CENTURI Aix Marseille University   (France)

Author keywords

Early seizures; N methyl d aspartate; Somatosensory cortex; aminobutyric acid

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; VOLTAGE GATED SODIUM CHANNEL; AMINO ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; GABAERGIC SYSTEM; GABAERGIC TRANSMISSION; NEOCORTEX; NERVE CELL EXCITABILITY; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SEIZURE; SIGNAL TRANSDUCTION; SOMATOSENSORY CORTEX; AGING; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; COMPLICATION; DRUG EFFECTS; EXCITATORY POSTSYNAPTIC POTENTIAL; IN VITRO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; METABOLISM; NERVE TRACT; NEWBORN; PATHOPHYSIOLOGY; PHYSIOLOGY; RECURRENT DISEASE; SPRAGUE DAWLEY RAT; TIME;

2-AMINO-5-PHOSPHONOVALERATE; AGING; ANIMALS; ANIMALS, NEWBORN; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; IN VITRO TECHNIQUES; INHIBITORY POSTSYNAPTIC POTENTIALS; NEOCORTEX; NEURAL PATHWAYS; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RECURRENCE; SEIZURES; SOMATOSENSORY CORTEX; TIME FACTORS;

EID: 77951155970     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2010.07179.x     Document Type: Article

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