Increased seizure susceptibility of the hippocampus compared with the neocortex of the immature mouse brain in vitro

Epilepsia

Volumn 46, Issue 3, 2005, Pages 356-366

  Abdelmalik, Peter A ^a,b   Burnham, W McIntyre ^a   Carlen, Peter L ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c TORONTO WESTERN HOSPITAL   (Canada)

Author keywords

Epilepsy; Ictogenesis; Intact hippocampus; Isolated frontal neocortical block; Seizure threshold

Indexed keywords

4 AMINOPYRIDINE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; GLUTAMATE RECEPTOR ANTAGONIST; MAGNESIUM; NIFEDIPINE; VALERIC ACID DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BRAIN REGION; CEREBROSPINAL FLUID FLOW; CONTROLLED STUDY; DEPOLARIZATION; DISEASE PREDISPOSITION; EPILEPTIC DISCHARGE; FOCAL EPILEPSY; HIPPOCAMPUS; MALE; MOUSE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; SEIZURE;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; CALCIUM CHANNEL BLOCKERS; CONVULSANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY, TEMPORAL LOBE; EVOKED POTENTIALS; EXCITATORY AMINO ACID ANTAGONISTS; FRONTAL LOBE; FUNCTIONAL LATERALITY; HIPPOCAMPUS; HYPOCALCEMIA; MAGNESIUM DEFICIENCY; MICE; MICE, INBRED C57BL; NEOCORTEX; NIFEDIPINE; SEIZURES; SYNAPTIC TRANSMISSION;

EID: 14944387091     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0013-9580.2005.34204.x     Document Type: Article

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