Spontaneous motor rhythms of the back and legs in a patient with a complete spinal cord transection

Neurorehabilitation and Neural Repair

Volumn 24, Issue 4, 2010, Pages 377-383

  Nadeau, Sylvie ^a,b   Jacquemin, Géraldine ^c   Fournier, Christine ^c   Lamarre, Yves ^b   Rossignol, Serge ^a,b  

^a Multidisciplinary Team in Locomotor Rehabilitation after Spinal Cord Injury and Stroke   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c Rehabilitation Institute of Montreal   (Canada)

Author keywords

Complete spinal section; Electromyography; Kinematics; Motor rhythms

Indexed keywords

BACLOFEN; CORTICOSTEROID;

ADULT; ARTICLE; CASE REPORT; ELECTROMYOGRAM; EXTENSOR MUSCLE; FLEXOR MUSCLE; HUMAN; KINEMATICS; LEG; LIMB MOVEMENT; MALE; MOTOR ACTIVITY; SENSORY STIMULATION; SPINAL CORD TRANSSECTION; TRUNK;

EID: 77951145074     PISSN: 15459683     EISSN: 15526844     Source Type: Journal    
DOI: 10.1177/1545968309349945     Document Type: Article

References (26)

1. Grillner S. Control of locomotion in bipeds, tetrapods, and fish. In: Brookhart JM, Mountcastle VB, eds. Handbook of Physiology: The Nervous System II. Bethesda, MD: American Physiological Society ; 1981: 1179-1236.
2. Rossignol S. Neural control of stereotypic limb movements. In: Rowell LB, Sheperd JT, eds. Handbook of Physiology, Section 12. Exercise: Regulation and Integration of Multiple Systems. New York, NY: Oxford University Press ; 1996: 173-216.
3. Barbeau H., Rossignol S. Recovery of locomotion after chronic spinalization in the adult cat. Brain Res. 1987 ; 412: 84-95.
4. Lhermitte J. La section totale de la Moelle Dorsale. Bourges, France: Tardy Pigelet ; 1919.
5. Bussel B., Roby-Brami A., Azouvi P. Organization of reflexes elicited by flexor reflex afferents in paraplegic man: evidence for a stepping generator. In: Jami L, Pierrot-Deseilligny E, Zytnicki D, eds. Muscle Afferents and Spinal Control of Movement. 1 st ed. Oxford, UK: Pergamon ; 1992: 427-432.
6. Bussel BC, Roby-Brami A., Yakovleff A., Bennis N. Evidences for the presence of a spinal stepping generator in patients with a spinal cord section. In: Amblard B, Berthoz A, Clarac F, eds. Posture and Gait: Development, Adaptation and Modulation. Amsterdam, the Netherlands: Elsevier ; 1988: 273-278.
7. Calancie B., Needham-Shropshire B., Jacobs P., Willer K., Zych G., Green BA Involuntary stepping after chronic spinal cord injury. Evidence for a central rhythm generator for locomotion in man. Brain. 1994 ; 117: 1143-1159.
8. Calancie B. Spinal myoclonus after spinal cord injury. J Spinal Cord Med. 2006 ; 29: 413-424.
9. Kuhn RA Functional capacity of the isolated human spinal cord. Brain. 1950 ; 73: 1-51.
10. Barbeau H., Rossignol S. Enhancement of locomotor recovery following spinal cord injury. Curr Opin Neurol. 1994 ; 7: 517-524.
11. Dietz V., Harkema SJ Locomotor activity in spinal cord-injured persons. J Appl Physiol. 2004 ; 96: 1954-1960.
12. Scivoletto G., Ivanenko Y., Morganti B., et al. Plasticity of spinal centers in spinal cord injury patients: new concepts for gait evaluation and training. Neurorehabil Neural Repair. 2007 ; 21: 358-365.
13. Edgerton VR, Leon RD, Harkema SJ, et al. Retraining the injured spinal cord. J Physiol. 2001 ; 533: 15-22.
14. Behrman AL, Harkema SJ Locomotor training after human spinal cord injury: a series of case studies. Phys Ther. 2000 ; 80: 688-700.
15. Dietz V. Spinal cord pattern generators for locomotion. Clin Neurophysiol. 2003 ; 114: 1379-1389.
16. Wernig A., Nanassy A., Muller S. Laufband (treadmill) therapy in incomplete paraplegia and tetraplegia. J Neurotrauma. 1999 ; 16: 719-726.
17. Wernig A., Muller S., Nanassy A., Cagol E. Laufband therapy based on "rules of spinal locomotion" is effective in spinal cord injured persons. Eur J Neurosci. 1995 ; 7: 823-829.
18. Wernig A., Muller S. Laufband locomotion with body weight support improved walking in persons with severe spinal cord injuries. Paraplegia. 1992 ; 30: 229-238.
19. Harkema SJ Plasticity of interneuronal networks of the functionally isolated human spinal cord. Brain Res Rev. 2008 ; 57: 255-264.
20. Belanger M., Drew T., Provencher J., Rossignol S. A comparison of treadmill locomotion in adult cats before and after spinal transection. J Neurophysiol. 1996 ; 76: 471-491.
21. Vaidyanathan S., Soni BM, Sett P., Watt JW, Oo T., Bingley J. Pathophysiology of autonomic dysreflexia: long-term treatment with terazosin in adult and paediatric spinal cord injury patients manifesting recurrent dysreflexic episodes. Spinal Cord. 1998 ; 36: 761-770.
22. Rossignol S., Dubuc R., Gossard JP Dynamic sensorimotor interactions in locomotion. Physiol Rev. 2006 ; 86: 89-154.
23. Rossignol S., Barriere G., Alluin O., Frigon A. Re-expression of locomotor function after partial spinal cord injury. Physiology (Bethesda). 2009 ; 24: 127-139.
24. Pearson KG, Rossignol S. Fictive motor patterns in chronic spinal cats. J Neurophysiol. 1991 ; 66: 1874-1887.
25. Chau C., Barbeau H., Rossignol S. Effects of intrathecal a1- and a2-noradrenergic agonists and norepinephrine on locomotion in chronic spinal cats. J Neurophysiol. 1998 ; 79: 2941-2963.
26. Chau C., Barbeau H., Rossignol S. Early locomotor training with clonidine in spinal cats. J Neurophysiol. 1998 ; 79: 392-409.