Synthesis of antitumour (1H-1,2,3-triazol-4-yl)-4-hydroxycyclohexa-2,5- dien-1-ones by copper-catalysed Huisgen cycloadditions

Organic and Biomolecular Chemistry

Volumn 8, Issue 9, 2010, Pages 2078-2084

  McCarroll, Andrew J ^a   Matthews, Charles S ^b   Wells, Geoffrey ^a,c   Bradshaw, Tracey D ^b   Stevens, Malcolm F G ^a,b  

^a Pharminox Ltd   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELL LINES; COPPER SALT; CYCLOADDITION REACTION; CYCLOADDITIONS; ETHYNYL; INHIBITORY ACTIVITY; PHARMACOPHORES; RUTHENIUM CATALYSTS;

CELL CULTURE; NITROGEN COMPOUNDS; RUTHENIUM; SALTS;

CYCLOADDITION;

ANTINEOPLASTIC AGENT; COPPER; CYCLOHEXANONE DERIVATIVE; TRIAZOLE DERIVATIVE;

ARTICLE; CATALYSIS; CELL PROLIFERATION; CHEMISTRY; CYCLIZATION; DRUG EFFECT; DRUG SCREENING; HUMAN; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CATALYSIS; CELL LINE, TUMOR; CELL PROLIFERATION; COPPER; CYCLIZATION; CYCLOHEXANONES; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 77951141248     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b920039h     Document Type: Article

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