Pipoxolan inhibits proliferation of HL-60 human leukaemia cancer cells by arresting the cell cycle at the G0/G1 phase

Clinical and Experimental Pharmacology and Physiology

Volumn 37, Issue 5-6, 2010, Pages 605-612

  Sheu, Ming Jyh ^a   Chou, Pei Yu ^b   Huang, Chin Shiu ^c   Tsai, I Chun ^a   Chien, Yi Chung ^b   Lin, Sung Yuan ^a   Tsai, Huei Yann ^a   Cheng, Hsu Chen ^b   Wu, Chieh His ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c ASIA UNIVERSITY   (Taiwan)

Author keywords

Anti proliferation; Apoptosis; Caspase 3; Pipoxolan; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PIPOXOLAN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SCAVENGER; TRYPAN BLUE; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL PROLIFERATION; CELL STRAIN HL 60; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN HYDROLYSIS; PROTEIN INDUCTION; UPREGULATION; WESTERN BLOTTING; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CULTURE TECHNIQUE; DRUG EFFECTS; HL 60 CELL LINE; METABOLISM; MONONUCLEAR CELL; PATHOLOGY;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SURVIVAL; DIOXOLANES; DNA FRAGMENTATION; FLOW CYTOMETRY; G0 PHASE; G1 PHASE; HL-60 CELLS; HUMANS; LEUKOCYTES, MONONUCLEAR; MOLECULAR STRUCTURE; REACTIVE OXYGEN SPECIES;

EID: 77951121047     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2010.05358.x     Document Type: Article

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