Evaluation of the amphibian metamorphosis assay: exposure to the goitrogen methimazole and the endogenous thyroid hormone l-thyroxine

Environmental Toxicology and Chemistry

Volumn 29, Issue 4, 2010, Pages 869-880

  Coady, Katherine ^a   Marino, Troy ^a   Thomas, Johnson ^a   Currie, Rebecca ^a   Hancock, Gregg ^a   Crofoot, Jackie ^a   Mcnalley, Lindsay ^a   Mcfadden, Lisa ^a   Geter, David ^a   Klecka, Gary ^a  

^a DOW CHEMICAL COMPANY   (United States)

Author keywords

Amphibian metamorphosis assay; L thyroxine; Methimazole; Thyroid; Xenopus laevis

Indexed keywords

ACTIVE CHEMICALS; ACTIVE COMPOUNDS; AMPHIBIAN METAMORPHOSIS; AMPHIBIAN METAMORPHOSIS ASSAY; DEVELOPMENTAL STAGE; METAMORPHIC DEVELOPMENT; METHIMAZOLE; PHYSICAL STRESS; PHYSICAL STRESSORS; SCREENING PROGRAMS; THYROID HORMONES; TRUE NEGATIVE; U.S. ENVIRONMENTAL PROTECTION AGENCY; VALIDATION PROCESS; WET WEIGHT; XENOPUS LAEVIS; XENOPUS LAEVIS TADPOLES;

ENVIRONMENTAL PROTECTION AGENCY;

ANTITHYROID AGENT; LEVOTHYROXINE; THIAMAZOLE; THYROID HORMONE; THYROXINE; WATER POLLUTANT;

BIOASSAY; DETECTION METHOD; DRUG; EXPERIMENTAL STUDY; FROG; HISTOPATHOLOGY; METAMORPHOSIS; TOAD;

AMPHIBIAN METAMORPHOSIS ASSAY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASSAY; CONTROLLED STUDY; DEVELOPMENTAL STAGE; ENVIRONMENTAL EXPOSURE; FLOW RATE; GONAD; GONAD DEVELOPMENT; GOVERNMENT; HINDLIMB; HISTOPATHOLOGY; NONHUMAN; PHYSICAL STRESS; PRIORITY JOURNAL; RELIABILITY; SENSITIVITY AND SPECIFICITY; TADPOLE; THYROID GLAND; VALIDATION PROCESS; XENOPUS LAEVIS; ANIMAL; BIOASSAY; DRUG EFFECTS; EMBRYOLOGY; FEMALE; GROWTH, DEVELOPMENT AND AGING; LARVA; MALE; METAMORPHOSIS; PATHOLOGY; PHYSIOLOGICAL STRESS; TOXICITY; WATER POLLUTANT;

AMPHIBIA; XENOPUS LAEVIS;

ANIMALS; ANTITHYROID AGENTS; ENDPOINT DETERMINATION; FEMALE; GONADS; LARVA; MALE; METAMORPHOSIS, BIOLOGICAL; METHIMAZOLE; STRESS, PHYSIOLOGICAL; THYROID GLAND; THYROXINE; WATER POLLUTANTS, CHEMICAL; XENOPUS LAEVIS;

EID: 77951081745     PISSN: 07307268     EISSN: 15528618     Source Type: Journal    
DOI: 10.1002/etc.74     Document Type: Article

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