Pharmacological characterization of the discriminative stimulus of inhaled 1,1,1-trichloroethane

Journal of Pharmacology and Experimental Therapeutics

Volumn 333, Issue 2, 2010, Pages 612-620

  Shelton, Keith L ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1,1 TRICHLOROETHANE; DIZOCILPINE; FENCLONINE; FLUMAZENIL; HALOTHANE; MECAMYLAMINE; MIDAZOLAM; MU OPIATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALTREXONE; NICOTINIC RECEPTOR; PHENCYCLIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DRUG DISCRIMINATION; EXPOSURE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VAPOR;

ADMINISTRATION, INHALATION; ANIMALS; BINDING SITES; DISCRIMINATION (PSYCHOLOGY); DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUMAZENIL; MALE; MICE; MICE, INBRED STRAINS; MIDAZOLAM; MORPHINE; PHENCYCLIDINE; RECEPTORS, GABA-A; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, NICOTINIC; RECEPTORS, OPIOID, MU; SIGNAL TRANSDUCTION; TRICHLOROETHANES;

EID: 77951070464     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.158949     Document Type: Article

References (40)

1. Bale AS, Meacham CA, Benignus VA, Bushnell PJ, and Shafer TJ (2005) Volatile organic compounds inhibit human and rat neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. Toxicol Appl Pharmacol 205:77-88. (Pubitemid 40693272)
2. Balster RL, Cruz SL, Howard MO, Dell CA, and Cottler LB (2009) Classification of abused inhalants. Addiction 104:878-882.
3. Beckstead MJ, Weiner JL, Eger EI 2nd, Gong DH, and Mihic SJ (2000) Glycine and γ-aminobutyric acid(A) receptor function is enhanced by inhaled drugs of abuse. Mol Pharmacol 57:1199-1205.
4. Borghese CM, Henderson LA, Bleck V, Trudell JR, and Harris RA (2003) Sites of excitatory and inhibitory actions of alcohols on neuronal α2β4 nicotinic acetylcholine receptors. J Pharmacol Exp Ther 307:42-52. (Pubitemid 37151890)
5. Bowen SE and Balster RL (1996) Effects of inhaled 1,1,1-trichloroethane on locomotor activity in mice. Neurotoxicol Teratol 18:77-81.
6. Bowen SE and Balster RL (1997) Desflurane, enflurane, isoflurane, and ether produce ethanol-like discriminative stimulus effects in mice. Pharmacol Biochem Behav 57:191-198.
7. Bowen SE and Balster RL (1998) A direct comparison of inhalant effects on locomotor activity and schedule-controlled behavior in mice. Exp Clin Psychopharmacol 6:235-247.
8. Bowen SE and Balster RL (2006) Tolerance and sensitization to inhaled 1,1,1-trichloroethane in mice: results from open-field behavior and a functional observational battery. Psychopharmacology (Berl) 185:405-415.
9. Bowen SE, Batis JC, Paez-Martinez N, and Cruz SL (2006) The last decade of solvent research in animal models of abuse: mechanistic and behavioral studies. Neurotoxicol Teratol 28:636-647. (Pubitemid 44829925)
10. Bowen SE, Wiley JL, Jones HE, and Balster RL (1999) Phencyclidine- and diazepam-like discriminative stimulus effects of inhalants in mice. Exp Clin Psychopharmacol 7:28-37.
11. Cruz SL, Balster RL, and Woodward JJ (2000) Effects of volatile solvents on recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. Br J Pharmacol 131:1303-1308.
12. Cruz SL, Gauthereau MY, Camacho-Munoz C, Lopez-Rubalcava C, and Balster RL (2003) Effects of inhaled toluene and 1,1,1-trichloroethane on seizures and death produced by N-methyl-D-aspartic acid in mice. Behav Brain Res 140:195-202. (Pubitemid 36313254)
13. Evans EB and Balster RL (1993) Inhaled 1,1,1-trichloroethane-produced physical dependence in mice: effects of drugs and vapors on withdrawal. J Pharmacol Exp Ther 264:726-733.
14. France CP, Moerschbaecher JM, and Woods JH (1991) MK-801 and related compounds in monkeys: discriminative stimulus effects and effects on a conditional discrimination. J Pharmacol Exp Ther 257:727-734.
15. Jarbe TU and Rollenhagen C (1978) Morphine as a discriminative cue in gerbils: drug generalization and antagonism. Psychopharmacology (Berl) 58:271-275.
16. King GS, Smialek JE, and Troutman WG (1985) Sudden death in adolescents resulting from the inhalation of typewriter correction fluid. J Am Med Assoc 253:1604-1606. (Pubitemid 15135834)
17. Knisely JS, Rees DC, and Balster RL (1990) Discriminative stimulus properties of toluene in the rat. Neurotoxicol Teratol 12:129-133.
18. Michaux P and Delevay-Le Gueut M (1980) Three cases of death in trichloroethylene addicts. Acta Med Leg Soc (Liege) 30:89-94.
19. Nelson JL and Zenick H (1986) The effect of trichloroethylene on male sexual behavior: possible opioid role. Neurobehav Toxicol Teratol 8:441-445.
20. Nishikawa K and Harrison NL (2003) The actions of sevoflurane and desflurane on the γ-aminobutyric acid receptor type A: effects of TM2 mutations in the α and β subunits. Anesthesiology 99:678-684. (Pubitemid 37051984)
21. Paez-Martinez N, Ambrosio E, Garcia-Lecumberri C, Rocha L, Montoya GL, and Cruz SL (2008) Toluene and TCE decrease binding to μ-opioid receptors, but not to benzodiazepine and NMDA receptors in mouse brain. Ann NY Acad Sci 1139:390-401.
22. Perouansky M, Kirson ED, and Yaari Y (1998) Mechanism of action of volatile anesthetics: effects of halothane on glutamate receptors in vitro. Toxicol Lett 100/101:65-69. (Pubitemid 29069129)
23. Rada EM, Tharakan EC, and Flood P (2003) Volatile anesthetics reduce agonist affinity at nicotinic acetylcholine receptors in the brain. Anesth Analg 96:108-111.
24. Rees DC, Knisely JS, Balster RL, Jordan S, and Breen TJ (1987a) Pentobarbital-like discriminative stimulus properties of halothane, 1,1,1-trichloroethane, isoamyl nitrite, flurothyl, and oxazepam in mice. J Pharmacol Exp Ther 241:507-515. (Pubitemid 17111555)
25. Rees DC, Knisely JS, Breen TJ, and Balster RL (1987b) Toluene, halothane, 1,1,1-trichloroethane, and oxazepam produce ethanol-like discriminative stimulus effects in mice. J Pharmacol Exp Ther 243:931-937. (Pubitemid 18017145)
26. Rice AS and Reynolds F (1987) Comparison of trichloroethylene and enflurane as adjuncts to nitrous oxide and relaxant anesthesia. Anesthesia 42:1320-1323.
27. Rowley TJ and Flood P (2008) Isoflurane prevents nicotine-evoked norepinephrine release from the mouse spinal cord at low clinical concentrations. Anesth Analg 107:885-889.
28. Salord F, Keita H, Lecharny JB, Henzel D, Desmonts JM, and Mantz J (1997) Halothane and isoflurane differentially affect the regulation of dopamine and γ-aminobutyric acid release mediated by presynaptic acetylcholine receptors in the rat striatum. Anesthesiology 86:632-641. (Pubitemid 27118347)
29. Sannerud CA and Ator NA (1995) Drug discrimination analysis of midazolam under a three-lever procedure: I. Dose-dependent differences in generalization and antagonism. J Pharmacol Exp Ther 272:100-111.
30. 2+ channel function by volatile organic solvents. J Pharmacol Exp Ther 315:1109-1118.
31. Shannon HE and Holtzman SG (1976) Blockade of the discriminative effects of morphine in the rat by naltrexone and naloxone. Psychopharmacology (Berl) 50:119-124.
32. Shelton KL (2007) Inhaled toluene vapor as a discriminative stimulus. Behav Pharmacol 18:219-229.
33. Shelton KL (2009) Discriminative stimulus effects of inhaled 1,1,1-trichloroethane in mice: comparison to other hydrocarbon vapors and volatile anesthetics. Psychopharmacology (Berl) 203:431-440.
34. Shelton KL and Balster RL (2004) Effects of abused inhalants and GABA-positive modulators in dizocilpine discriminating inbred mice. Pharmacol Biochem Behav 79:219-228.
35. Shelton KL and Slavova-Hernandez G (2009) Characterization of an inhaled toluene drug discrimination in mice: effect of exposure conditions and route of administration. Pharmacol Biochem Behav 92:614-620.
36. Solinas M and Goldberg SR (2005) Involvement of μ-, delta- and κ-opioid receptor subtypes in the discriminative-stimulus effects of delta-9-tetrahydrocannabinol (THC) in rats. Psychopharmacology (Berl) 179:804-812. (Pubitemid 40767900)
37. Tallarida RJ and Murray RB (1986) Manual of Pharmacological Calculations with Computer Programs, Springer-Verlag, New York.
38. Varvel SA, James JR, Bowen S, Rosecrans JA, and Karan LD (1999) Discriminative stimulus (DS) properties of nicotine in the C57BL/6 mouse. Pharmacol Biochem Behav 63:27-32. (Pubitemid 29206558)
39. Westphalen RI and Hemmings HC Jr (2006) Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release. J Pharmacol Exp Ther 316:216-223. (Pubitemid 41832599)
40. Zhang L, Oz M, Stewart RR, Peoples RW, and Weight FF (1997) Volatile general anaesthetic actions on recombinant nACh α 7, 5-HT3 and chimeric nACh 7-5- HT3 receptors expressed in Xenopus oocytes. Br J Pharmacol 120:353-355. (Pubitemid 27052831)