Isoflurane prevents nicotine-evoked norepinephrine release from the mouse spinal cord at low clinical concentrations

Anesthesia and Analgesia

Volumn 107, Issue 3, 2008, Pages 885-889

  Rowley, Thomas J ^a   Flood, Pamela ^a,b  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA BUNGAROTOXIN; CHOLINE; ISOFLURANE; LIGAND; NICOTINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BETA2; NORADRENALIN; TRITIUM; TRITIUM NOREPINEPHRINE; UNCLASSIFIED DRUG; BUNGAROTOXIN; INHALATION ANESTHETIC AGENT;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; EVOKED RESPONSE; FACILITATION; FEMALE; GENE EXPRESSION; IN VIVO STUDY; MAXIMUM ALLOWABLE CONCENTRATION; MOLECULAR MIMICRY; MOUSE; NOCICEPTION; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; SPINAL CORD; TRANSGENIC ANIMAL; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION REGULATION; METABOLISM; NERVE FIBER; PATHOLOGY;

ANESTHETICS, INHALATION; ANIMALS; AXONS; BUNGAROTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION; ISOFLURANE; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; NICOTINE; NOREPINEPHRINE; RECEPTORS, NICOTINIC; SPINAL CORD;

EID: 51349169725     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ane.0000287646.85834.1a     Document Type: Article

References (25)

1. Flood P, Ramirez-Latorre J, Role L. -4-2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but -7-type nicotinic acetylcholine receptors are unaffected. Anesthesiology 1997;86:859-65
2. Violet JM, Downie DL, Nakisa RC, Lieb WR, Franks NP. Differential sensitivities of mammalian neuronal and muscle nicotinic acetylcholine receptors to general anesthetics. Anesthesiology 1997;86:866-74
3. Zhang Y, Eger EI II, Dutton RC, Sonner JM. Inhaled anesthetics have hyperalgesic effects at 0.1 minimum alveolar anesthetic concentration. Anesth Analg 2000;91:462-6
4. Flood P, Sonner J, Gong D, Coates K. Isoflurane hyperalgesia is modulated by nicotinic inhibition. Anesthesiology 2002;97:192-8
5. Dundee JW, Moore J. Alterations in response to somatic pain associated with anaesthesia. IV. The effect of subanaesthetic concentrations of inhalation agents. Br J Anaesth 1960;32:453-9
6. Li X, Eisenach JC. Nicotinic acetylcholine receptor regulation of spinal norepinephrine release. Anesthesiology 2002;96:1450-6
7. Li X, Rainnie DG, McCarley RW, Greene RW. Presynaptic nicotinic receptors facilitate monoaminergic transmission. J Neurosci 1998;18:1904-12
8. Chiari A, Tobin JR, Pan HL, Hood DD, Eisenach JC. Sex differences in cholinergic analgesia I: a supplemental nicotinic mechanism in normal females. Anesthesiology 1999;91:1447-54
9. Rueter LE, Meyer MD, Decker MW. Spinal mechanisms underlying A-85380-induced effects on acute thermal pain. Brain Res 2000;872:93-101
10. Anderson DJ, Puttfarcken PS, Jacobs I, Faltynek C. Assessment of nicotinic acetylcholine receptor-mediated release of [(3)H]- norepinephrine from rat brain slices using a new 96-well format assay. Neuropharmacology 2000;39:2663-72
11. Rao TS, Correa LD, Reid RT, Lloyd GK. Evaluation of antinociceptive effects of neuronal nicotinic acetylcholine receptor (NAChR) ligands in the rat tail-flick assay. Neuropharmacology 1996;35:393-405
12. Lavand'homme PM, Eisenach JC. Sex differences in cholinergic analgesia II: differing mechanisms in two models of allodynia. Anesthesiology 1999;91:1455-61
13. Rowley TJ, Daniel D, Flood P. The role of adrenergic and cholinergic transmission in volatile anesthetic-induced pain enhancement. Anesth Analg 2005;100:991-5
14. Marubio LM, del Mar Arroyo-Jimenez M, Cordero-Erausquin M, Lena C, Le Novere N, de Kerchove d'Exaerde A, Huchet M, Damaj MI, Changeux JP. Reduced antinociception in mice lacking neuronal nicotinic receptor subunits. Nature 1999;398:805-10
15. Colquhoun LM, Patrick JW. Pharmacology of neuronal nicotinic acetylcholine receptor subtypes. Adv Pharmacol 1997;39:191-220
16. Papke RL, Bencherif M, Lippiello P. An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the -7 subtype. Neurosci Lett 1996;213:201-4
17. Sagen J, Proudfit HK. Effect of intrathecally administered noradrenergic antagonists on nociception in the rat. Brain Res 1984;310:295-301
18. Damaj MI, Glassco W, Aceto MD, Martin BR. Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist. J Pharmacol Exp Ther 1999;291:390-8
19. Damaj MI, Meyer EM, Martin BR. The antinociceptive effects of -7 nicotinic agonists in an acute pain model. Neuropharmacology 2000;39:2785-91
20. Hamurtekin E, Sibel Gurun M. The antinociceptive effects of centrally administered CDP-choline on acute pain models in rats: the involvement of cholinergic system. Brain Res 2006;1117:92-100
21. Flood P, Coates KM. Sensitivity of the alpha7 nicotinic acetylcholine receptor to isoflurane may depend on receptor inactivation. Anesth Analg 2002;95:83-7
22. Virginio C, Giacometti A, Aldegheri L, Rimland JM, Terstappen GC. Pharmacological properties of rat -7 nicotinic receptors expressed in native and recombinant cell systems. Eur J Pharmacol 2002;445:153-61
23. Khiroug SS, Harkness PC, Lamb PW, Sudweeks SN, Khiroug L, Millar NS, Yakel JL. Rat nicotinic ACh receptor -7 and -2 subunits co-assemble to form functional heteromeric nicotinic receptor channels. J Physiol 2002;540:425-34
24. Girod R, Crabtree G, Ernstrom G, Ramirez-Latorre J, McGehee D, Turner J, Role L. Heteromeric complexes of -5 and/or -7 subunits. Effects of calcium and potential role in nicotine-induced presynaptic facilitation. Ann N Y Acad Sci 1999;868:578-90
25. Lips KS, Pfeil U, Kummer W. Coexpression of -9 and -10 nicotinic acetylcholine receptors in rat dorsal root ganglion neurons. Neuroscience 2002;115:1-5