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Volumn 107, Issue 15, 2010, Pages 6782-6787

Residues in the central β-hairpin of the DNA helicase of bacteriophage T7 are important in DNA unwinding

Author keywords

Beta hairpin; DNA replication; Leading strand synthesis; Oligomerization; Sliding helicase

Indexed keywords

ASPARAGINE; DNA POLYMERASE; HELICASE; HISTIDINE; LEUCINE;

EID: 77951036168     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1002734107     Document Type: Article
Times cited : (11)

References (36)
  • 1
    • 67650741773 scopus 로고    scopus 로고
    • Motors, switches, and contacts in the replisome
    • Hamdan SM, Richardson CC (2009) Motors, switches, and contacts in the replisome. Annu Rev Biochem 78:205-243.
    • (2009) Annu Rev Biochem , vol.78 , pp. 205-243
    • Hamdan, S.M.1    Richardson, C.C.2
  • 2
    • 34548638261 scopus 로고    scopus 로고
    • Structure and mechanism of helicases and nucleic acid translocases
    • Singleton MR, Dillingham MS, Wigley DB (2007) Structure and mechanism of helicases and nucleic acid translocases. Annu Rev Biochem 76:23-50.
    • (2007) Annu Rev Biochem , vol.76 , pp. 23-50
    • Singleton, M.R.1    Dillingham, M.S.2    Wigley, D.B.3
  • 3
    • 0029039925 scopus 로고
    • Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases
    • Egelman EH, Yu X, Wild R, Hingorani MM, Patel SS (1995) Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases. Proc Natl Acad Sci USA 92:3869-3873.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3869-3873
    • Egelman, E.H.1    Yu, X.2    Wild, R.3    Hingorani, M.M.4    Patel, S.S.5
  • 4
    • 0036382873 scopus 로고    scopus 로고
    • T7 DNA helicase: A molecular motor that processively and unidirectionally translocates along single-stranded DNA
    • Kim DE, Narayan M, Patel SS (2002) T7 DNA helicase: A molecular motor that processively and unidirectionally translocates along single-stranded DNA. J Mol Biol 321:807-819.
    • (2002) J Mol Biol , vol.321 , pp. 807-819
    • Kim, D.E.1    Narayan, M.2    Patel, S.S.3
  • 6
    • 31844453991 scopus 로고    scopus 로고
    • DNA primase acts as a molecular brake in DNA replication
    • Lee JB, et al. (2006) DNA primase acts as a molecular brake in DNA replication. Nature 439:621-624.
    • (2006) Nature , vol.439 , pp. 621-624
    • Lee, J.B.1
  • 7
    • 19644399070 scopus 로고    scopus 로고
    • DNA synthesis provides the driving force to accelerate DNA unwinding by a helicase
    • Stano NM, et al. (2005) DNA synthesis provides the driving force to accelerate DNA unwinding by a helicase. Nature 435:370-373.
    • (2005) Nature , vol.435 , pp. 370-373
    • Stano, N.M.1
  • 8
    • 0034625236 scopus 로고    scopus 로고
    • Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides
    • Singleton MR, Sawaya MR, Ellenberger T, Wigley DB (2000) Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides. Cell 101:589-600.
    • (2000) Cell , vol.101 , pp. 589-600
    • Singleton, M.R.1    Sawaya, M.R.2    Ellenberger, T.3    Wigley, D.B.4
  • 9
    • 30744451401 scopus 로고    scopus 로고
    • DNA-induced switch from independent to sequential dTTP hydrolysis in the bacteriophage T7 DNA helicase
    • DOI 10.1016/j.molcel.2005.11.027, PII S1097276505018150
    • Crampton DJ, Mukherjee S, Richardson CC (2006) DNA-induced switch from independent to sequential dTTP hydrolysis in the bacteriophage T7 DNA helicase. Mol Cell 21:165-174. (Pubitemid 43099933)
    • (2006) Molecular Cell , vol.21 , Issue.2 , pp. 165-174
    • Crampton, D.J.1    Mukherjee, S.2    Richardson, C.C.3
  • 10
    • 0029092684 scopus 로고
    • A domain of the gene 4 helicase/primase of bacteriophage T7 required for the formation of an active hexamer
    • Notarnicola SM, Park K, Griffith JD, Richardson CC (1995) A domain of the gene 4 helicase/primase of bacteriophage T7 required for the formation of an active hexamer. J Biol Chem 270:20215-20224.
    • (1995) J Biol Chem , vol.270 , pp. 20215-20224
    • Notarnicola, S.M.1    Park, K.2    Griffith, J.D.3    Richardson, C.C.4
  • 11
    • 10244263498 scopus 로고    scopus 로고
    • Biochemical analysis of mutant T7 primase/helicase proteins defective in DNA binding, nucleotide hydrolysis, and the coupling of hydrolysis with DNA unwinding
    • DOI 10.1074/jbc.271.43.26825
    • Washington MT, Rosenberg AH, Griffin K, Studier FW, Patel SS (1996) Biochemical analysis of mutant T7 primase/helicase proteins defective in DNA-binding, nucleotide hydrolysis, and the coupling of hydrolysis with DNA unwinding. J Biol Chem 271:26825-26834. (Pubitemid 26359093)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.43 , pp. 26825-26834
    • Todd Washington, M.1    Rosenberg, A.H.2    Griffin, K.3    William Studier, F.4    Patel, S.S.5
  • 12
    • 0026584599 scopus 로고
    • Structure of the recA protein-ADP complex
    • Story RM, Steitz TA (1992) Structure of the recA protein-ADP complex. Nature 355:374-376.
    • (1992) Nature , vol.355 , pp. 374-376
    • Story, R.M.1    Steitz, T.A.2
  • 14
    • 33746375404 scopus 로고    scopus 로고
    • Mechanism of DNA translocation in a replicative hexameric helicase
    • DOI 10.1038/nature04943, PII NATURE04943
    • Enemark EJ, Joshua-Tor L (2006) Mechanism of DNA translocation in a replicative hexameric helicase. Nature 442:270-275. (Pubitemid 44114897)
    • (2006) Nature , vol.442 , Issue.7100 , pp. 270-275
    • Enemark, E.J.1    Joshua-Tor, L.2
  • 15
    • 37849024100 scopus 로고    scopus 로고
    • The structure of a DnaB-family replicative helicase and its interactions with primase
    • Wang G, et al. (2008) The structure of a DnaB-family replicative helicase and its interactions with primase. Nat Struct Mol Biol 15:94-100.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 94-100
    • Wang, G.1
  • 16
    • 0021112593 scopus 로고
    • Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase
    • Lechner RL, Engler MJ, Richardson CC (1983) Characterization of strand displacement synthesis catalyzed by bacteriophage T7 DNA polymerase. J Biol Chem 258:11174-11184.
    • (1983) J Biol Chem , vol.258 , pp. 11174-11184
    • Lechner, R.L.1    Engler, M.J.2    Richardson, C.C.3
  • 17
    • 0021112580 scopus 로고
    • A preformed, topologically stable replication fork. Characterization of leading strand DNA synthesis catalyzed by T7 DNA polymerase and T7 gene 4 protein
    • Lechner RL, Richardson CC (1983) A preformed, topologically stable replication fork. Characterization of leading strand DNA synthesis catalyzed by T7 DNA polymerase and T7 gene 4 protein. J Biol Chem 258:11185-11196.
    • (1983) J Biol Chem , vol.258 , pp. 11185-11196
    • Lechner, R.L.1    Richardson, C.C.2
  • 18
    • 0026033193 scopus 로고
    • Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant
    • Patel SS, Wong I, Johnson KA (1991) Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. Biochemistry 30:511-525.
    • (1991) Biochemistry , vol.30 , pp. 511-525
    • Patel, S.S.1    Wong, I.2    Johnson, K.A.3
  • 19
    • 0031465797 scopus 로고    scopus 로고
    • Asymmetric interactions of hexameric bacteriophage T7 DNA helicase with the 5'- And 3'-tails of the forked DNA substrate
    • DOI 10.1074/jbc.272.51.32267
    • Ahnert P, Patel SS (1997) Asymmetric interactions of hexameric bacteriophage T7 DNA helicase with the 5′- and 3′-tails of the forked DNA substrate. J Biol Chem 272:32267-32273. (Pubitemid 28011905)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.51 , pp. 32267-32273
    • Ahnert, P.1    Patel, S.S.2
  • 20
    • 33745678945 scopus 로고    scopus 로고
    • Oligomeric States of Bacteriophage T7 Gene 4 Primase/Helicase
    • DOI 10.1016/j.jmb.2006.05.037, PII S002228360600619X
    • Crampton DJ, Ohi M, Qimron U, Walz T, Richardson CC (2006) Oligomeric states of bacteriophage T7 gene 4 primase/helicase. J Mol Biol 360:667-677. (Pubitemid 43975114)
    • (2006) Journal of Molecular Biology , vol.360 , Issue.3 , pp. 667-677
    • Crampton, D.J.1    Ohi, M.2    Qimron, U.3    Walz, T.4    Richardson, C.C.5
  • 21
    • 34547740094 scopus 로고    scopus 로고
    • Dynamic DNA helicase-DNA polymerase interactions assure processive replication fork movement
    • Hamdan SM, et al. (2007) Dynamic DNA helicase-DNA polymerase interactions assure processive replication fork movement. Mol Cell 27:539-549.
    • (2007) Mol Cell , vol.27 , pp. 539-549
    • Hamdan, S.M.1
  • 23
    • 33947251128 scopus 로고    scopus 로고
    • Adjacent Residues in the E1 Initiator beta-Hairpin Define Different Roles of the beta-Hairpin in Ori Melting, Helicase Loading, and Helicase Activity
    • DOI 10.1016/j.molcel.2007.02.009, PII S1097276507001086
    • Liu X, Schuck S, Stenlund A (2007) Adjacent residues in the E1 initiator beta-hairpin define different roles of the beta-hairpin in Ori melting, helicase loading, and helicase activity. Mol Cell 25:825-837. (Pubitemid 46436527)
    • (2007) Molecular Cell , vol.25 , Issue.6 , pp. 825-837
    • Liu, X.1    Schuck, S.2    Stenlund, A.3
  • 24
    • 0032716810 scopus 로고    scopus 로고
    • Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7
    • Sawaya MR, Guo S, Tabor S, Richardson CC, Ellenberger T (1999) Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7. Cell 99:167-177. (Pubitemid 129746824)
    • (1999) Cell , vol.99 , Issue.2 , pp. 167-177
    • Sawaya, M.R.1    Guo, S.2    Tabor, S.3    Richardson, C.C.4    Ellenberger, T.5
  • 25
    • 0345276497 scopus 로고    scopus 로고
    • The crystal structure of the bifunctional primase-helicase of bacteriophage T7
    • DOI 10.1016/S1097-2765(03)00442-8
    • Toth EA, Li Y, Sawaya MR, Cheng Y, Ellenberger T (2003) The crystal structure of the bifunctional primase-helicase of bacteriophage T7. Mol Cell 12:1113-1123. (Pubitemid 37487922)
    • (2003) Molecular Cell , vol.12 , Issue.5 , pp. 1113-1123
    • Toth, E.A.1    Li, Y.2    Sawaya, M.R.3    Cheng, Y.4    Ellenberger, T.5
  • 26
    • 0034600838 scopus 로고    scopus 로고
    • A ring-opening mechanism for DNA binding in the central channel of the T7 helicase-primase protein
    • Ahnert P, Picha KM, Patel SS (2000) A ring-opening mechanism for DNA binding in the central channel of the T7 helicase-primase protein. EMBO J 19:3418-3427. (Pubitemid 30428219)
    • (2000) EMBO Journal , vol.19 , Issue.13 , pp. 3418-3427
    • Ahnert, P.1    Picha, K.M.2    Patel, S.S.3
  • 27
    • 0033792010 scopus 로고    scopus 로고
    • Two different oligomeric states of the RuvB branch migration motor protein as revealed by electron microscopy
    • Miyata T, et al. (2000) Two different oligomeric states of the RuvB branch migration motor protein as revealed by electron microscopy. J Struct Biol 131:83-89.
    • (2000) J Struct Biol , vol.131 , pp. 83-89
    • Miyata, T.1
  • 29
    • 48249141100 scopus 로고    scopus 로고
    • Communication between subunits critical to DNA binding by hexameric helicase of bacteriophage T7
    • Lee SJ, Qimron U, Richardson CC (2008) Communication between subunits critical to DNA binding by hexameric helicase of bacteriophage T7. Proc Natl Acad Sci USA 105:8908-8913.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8908-8913
    • Lee, S.J.1    Qimron, U.2    Richardson, C.C.3
  • 30
    • 20444440763 scopus 로고    scopus 로고
    • A Brownian motor mechanism of translocation and strand separation by hepatitis C virus helicase
    • DOI 10.1038/nsmb920
    • Levin MK, Gurjar M, Patel SS (2005) A Brownian motor mechanism of translocation and strand separation by hepatitis C virus helicase. Nat Struct Mol Biol 12:429-435. (Pubitemid 43085903)
    • (2005) Nature Structural and Molecular Biology , vol.12 , Issue.5 , pp. 429-435
    • Levin, M.K.1    Gurjar, M.2    Patel, S.S.3
  • 31
    • 33745823112 scopus 로고    scopus 로고
    • Mechanisms of helicases
    • Patel SS, Donmez I (2006) Mechanisms of helicases. J Biol Chem 281:18265-18268.
    • (2006) J Biol Chem , vol.281 , pp. 18265-18268
    • Patel, S.S.1    Donmez, I.2
  • 32
    • 0032478641 scopus 로고    scopus 로고
    • Increased DNA unwinding efficiency of bacteriophage T7 DNA helicase mutant protein 4A'/E348K
    • DOI 10.1074/jbc.273.14.7880
    • Washington MT, Patel SS (1998) Increased DNA unwinding efficiency of bacteriophage T7 DNA helicase mutant protein 4A′/E348K. J Biol Chem 273:7880-7887. (Pubitemid 28168833)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.14 , pp. 7880-7887
    • Washington, M.T.1    Patel, S.S.2
  • 33
    • 0029905072 scopus 로고    scopus 로고
    • A coupled complex of T4 DNA replication helicase (gp41) and polymerase (gp43) can perform rapid and processive DNA strand-displacement synthesis
    • DOI 10.1073/pnas.93.25.14456
    • Dong F, Weitzel SE, Von Hippel PH (1996) A coupled complex of T4 DNA replication helicase (gp41) and polymerase (gp43) can perform rapid and processive DNA strand-displacement synthesis. Proc Natl Acad Sci USA 93:14456-14461. (Pubitemid 26418988)
    • (1996) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , Issue.25 , pp. 14456-14461
    • Dong, F.1    Weitzel, S.E.2    Von Hippel, P.H.3
  • 34
    • 0030070356 scopus 로고    scopus 로고
    • Coupling of a replicative polymerase and helicase: A tau-DnaB interaction mediates rapid replication fork movement
    • DOI 10.1016/S0092-8674(00)81039-9
    • Kim S, Dallmann HG, McHenry CS, Marians KJ (1996) Coupling of a replicative polymerase and helicase: A tau-DnaB interaction mediates rapid replication fork movement. Cell 84:643-650. (Pubitemid 26071744)
    • (1996) Cell , vol.84 , Issue.4 , pp. 643-650
    • Kim, S.1    Dallmann, H.G.2    McHenry, C.S.3    Marians, K.J.4
  • 35
    • 34250766751 scopus 로고    scopus 로고
    • Single-Molecule Studies Reveal Dynamics of DNA Unwinding by the Ring-Shaped T7 Helicase
    • DOI 10.1016/j.cell.2007.04.038, PII S0092867407005843
    • Johnson DS, Bai L, Smith BY, Patel SS, Wang MD (2007) Single-molecule studies reveal dynamics of DNA unwinding by the ring-shaped T7 helicase. Cell 129:1299-1309 (Pubitemid 46962089)
    • (2007) Cell , vol.129 , Issue.7 , pp. 1299-1309
    • Johnson, D.S.1    Bai, L.2    Smith, B.Y.3    Patel, S.S.4    Wang, M.D.5
  • 36
    • 67649803032 scopus 로고    scopus 로고
    • Promiscuous usage of nucleotides by the DNA helicase of bacteriophage T7: Determinants of nucleotide specificity
    • Satapathy AK, Crampton DJ, Beauchamp BB, Richardson CC (2009) Promiscuous usage of nucleotides by the DNA helicase of bacteriophage T7: Determinants of nucleotide specificity. J Biol Chem 284:14286-14295.
    • (2009) J Biol Chem , vol.284 , pp. 14286-14295
    • Satapathy, A.K.1    Crampton, D.J.2    Beauchamp, B.B.3    Richardson, C.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.