Efficacy and safety of topical WBI-1001 in the treatment of atopic dermatitis: Results from a phase 2A, randomized, placebo-controlled clinical trial

Archives of Dermatology

Volumn 146, Issue 4, 2010, Pages 446-449

  Bissonnette, Robert ^a   Chen, Genhui ^b   Bolduc, Chantal ^a   Maari, Catherine ^a   Lyle, Michael ^b   Tang, Liren ^b   Webster, John ^b   Zhou, Youwen ^c  

^a INNOVADERM RESEARCH   (Canada)

^b Welichem Biotech Inc   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

2 ISOPROPYL 5 (2 PHENYLETHENYL)BENZENE 1,3 DIOL; UNCLASSIFIED DRUG; WBI 1001;

ATOPIC DERMATITIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; HUMAN; LETTER; PAPULE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RASH; TREATMENT RESPONSE;

ADMINISTRATION, TOPICAL; ADULT; BENZENE DERIVATIVES; DERMATITIS, ATOPIC; DOUBLE-BLIND METHOD; DRUG CARRIERS; FEMALE; HUMANS; IMMUNOLOGIC FACTORS; MALE; TREATMENT OUTCOME;

EID: 77951031588     PISSN: 0003987X     EISSN: 15383652     Source Type: Journal    
DOI: 10.1001/archdermatol.2010.34     Document Type: Letter

References (5)

1. Langley RG, Luger TA, Cork MJ, Schneider D, Paul C. An update on the safety and tolerability of pimecrolimus cream 1%: evidence from clinical trials and post-marketing surveillance. Dermatology. 2007;215(suppl 1):27-44. (Pubitemid 350308378)
2. Callen J, Chamlin S, Eichenfield LF, et al. A systematic review of the safety of topical therapies for atopic dermatitis. Br J Dermatol. 2007;156(2):203-221. (Pubitemid 46095948)
3. Hanifin JM, Thurston M, Omoto M, Cherill R, Tofte SJ, Graeber M; EASI Evaluator Group. The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis. EASI Evaluator Group. Exp Dermatol. 2001;10(1):11-18. (Pubitemid 32098039)
4. European Task Force on Atopic Dermatitis. Severity scoring of atopic dermatitis: the SCORAD index: consensus report of the European Task Force on Atopic Dermatitis. Dermatology. 1993;186(1):23-31.
5. Bernard LA, Eichenfield LF. Topical immunomodulators for atopic dermatitis. Curr Opin Pediatr. 2002;14(4):414-418.