Design, synthesis, characterization, and antibacterial activity of {5-chloro-2-[(3-substitutedphenyl-1,2,4-oxadiazol-5-yl)-methoxy]-phenyl} -(phenyl)-methanones

European Journal of Medicinal Chemistry

Volumn 45, Issue 6, 2010, Pages 2677-2682

  Rai, Neithnadka Premsai ^a,c   Narayanaswamy, Venugopala Katharigatta ^b   Govender, Thavendran ^b   Manuprasad, B K ^a   Shashikanth, Sheena ^a   Arunachalam, Pirama Nayagam ^c  

^a UNIVERSITY OF MYSORE   (India)

^b UNIVERSITY OF KWAZULU NATAL   (South Africa)

^c SYNGENE INTERNATIONAL LTD   (India)

Author keywords

1,2,4 Oxadiazoles; Antibacterial activity; Substituted methanones

Indexed keywords

2,5 DIFLUORO N' HYDROXY 4 METHYLBENZIMIDAMIDE; 3 (3 CHLORO 4 FLUOROPHENYL) 5 (CHLOROMETHYL) 1,2,4 OXADIAZOLE; 3 CHLORO 4 FLUORO N' HYDROXYBENZIMIDAMIDE; 4 ETHOXY N' HYDROXYBENZIMIDAMIDE; 4 FLUORO N' HYDROXY 3 METHOXYBENZIMIDAMIDE; 4 FLUORO N' HYDROXY 3 METHYLBENZIMIDAMIDE; 4 FLUORO N' HYDROXYBENZIMIDAMIDE; 5 (CHLOROMETHYL) 3 (2,5 DIFLUORO 4 METHYLPHENYL) 1,2,4 OXADIAZOLE; 5 (CHLOROMETHYL) 3 (4 ETHOXYPHENYL) 1,2,4 OXADIAZOLE; 5 (CHLOROMETHYL) 3 (4 FLUORO 3 METHOXYPHENYL) 1,2,4 OXADIAZOLE; 5 (CHLOROMETHYL) 3 (4 FLUORO 3 METHYLPHENYL) 1,2,4 OXADIAZOLE; 5 (CHLOROMETHYL) 3 (4 FLUOROPHENYL) 1,2,4 OXADIAZOLE; 5 (CHLOROMETHYL) 3 (4 IODOPHENYL) 1,2,4 OXADIAZOLE; 5 (CHLOROMETHYL) 3 (4 ISOPROPYLPHENYL) 1,2,4 OXADIAZOLE; 5 (CHLOROMETHYL) 3 PHENYL 1,2,4 OXADIAZOLE; [5 CHLORO 2 [(3 (2,5 DIFLUORO 4 METHYLPHENYL) 1,2,4 OXADIAZOL 5 YL) METHOXY] PHENYL](PHENYL) METHANONE; [5 CHLORO 2 [(3 (3 CHLORO 4 FLUOROPHENYL) 1,2,4 OXADIAZOL 5 YL) METHOXY] PHENYL](PHENYL) METHANONE; [5 CHLORO 2 [(3 (4 ETHOXYPHENYL) 1,2,4 OXADIAZOL 5 YL) METHOXY] PHENYL](PHENYL) METHANONE; [5 CHLORO 2 [(3 (4 FLUORO 3 METHOXYPHENYL) 1,2,4 OXADIAZOL 5 YL) METHOXY] PHENYL](PHENYL) METHANONE; [5 CHLORO 2 [(3 (4 FLUORO 3 METHYLPHENYL) 1,2,4 OXADIAZOL 5 YL) METHOXY] PHENYL](PHENYL) METHANONE; [5 CHLORO 2 [(3 (4 FLUOROPHENYL) 1,2,4 OXADIAZOL 5 YL) METHOXY] PHENYL](PHENYL) METHANONE; [5 CHLORO 2 [(3 (4 IODOPHENYL) 1,2,4 OXADIAZOL 5 YL) METHOXY] PHENYL](PHENYL) METHANONE; [5 CHLORO 2 [(3 (4 ISOPROPYLPHENYL) 1,2,4 OXADIAZOL 5 YL) METHOXY] PHENYL](PHENYL) METHANONE; [5 CHLORO 2 [(3 (PHENYL) 1,2,4 OXADIAZOL 5 YL) METHOXY] PHENYL](PHENYL) METHANONE; AGAR; ANTIINFECTIVE AGENT; N' HYDROXY 4 IODOBENZIMIDAMIDE; N' HYDROXY 4 ISOPROPYLBENZIMIDAMIDE; N' HYDROXYBENZIMIDAMIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; DRUG DESIGN; DRUG SYNTHESIS; ESCHERICHIA COLI; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; MICROTITER PLATE ASSAY; MINIMUM INHIBITORY CONCENTRATION; NUCLEAR MAGNETIC RESONANCE; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BACTERIA; BENZOPHENONES; DRUG DESIGN; MAGNETIC RESONANCE SPECTROSCOPY;

EID: 77950933177     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.02.021     Document Type: Article

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