Stimulatory effects of Cuminum cyminum and flavonoid glycoside on Cyclosporine-A and restraint stress induced immune-suppression in Swiss albino mice

Chemico-Biological Interactions

Volumn 185, Issue 1, 2010, Pages 66-72

  Chauhan, Prashant Singh ^a   Satti, Naresh Kumar ^a   Suri, Krishan Avtar ^a   Amina, Musarat ^a   Bani, Sarang ^a  

^a CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Corticosterone; Cuminum cyminum; Cyclosporine A; Cytokines; Restraint stress; T cells

Indexed keywords

3',5 DIHYDROXYFLAVONE 7 O BETA DEXTRO GALACTURONIDE 4' O BETA DEXTRO GLUCOPYRANOSIDE; CD4 ANTIGEN; CD8 ANTIGEN; CORTICOSTERONE; CUMIN EXTRACT; CYCLOSPORIN A; FLAVONOID GLYCOSIDE; HERBACEOUS AGENT; LEVAMISOLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CUMIN; DRUG POTENCY; IMMOBILIZATION STRESS; IMMUNE DEFICIENCY; IMMUNOMODULATION; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SPLEEN WEIGHT; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; TH1 CELL; THYMUS;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CORTICOSTERONE; CUMINUM; CYCLOSPORINE; CYTOKINES; FLAVONOIDS; GLYCOSIDES; IMMUNOLOGIC FACTORS; IMMUNOSUPPRESSIVE AGENTS; MICE; ORGAN SIZE; T-LYMPHOCYTES;

ANIMALIA; CUMINUM CYMINUM; MUS;

EID: 77950926661     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.02.016     Document Type: Article

References (18)

1. Sharma P. Chikitasasthana. Chaukhamba Orientalia 1983, Charaka Samhita, Varanasi, India, p. 54.
2. Thatte U.M., Dahanukar S.A. Ayurveda and contemporary scientific thought. Trends Pharmacol. Sci. 1986, 7:247.
3. Bin H.B., Haque R., Parvez S., Pandey S., Sayeed I., Raisuddin S. Immunomodulatory effects of fenugreek (Trigonella foenum graecum L.) extract in mice. Int. J. Immunopharmacol. 2003, 3:257-265.
4. Ishikawa T., Takayanagi T., Kitajima J. Water soluble constituents of Cuminum: monoterpenoid glucosides. Chem. Pharm. Bull. 2002, 50:1471-1478.
5. Satti N.K., Amina M., Dutt P., Sharma V.K., Sharma P., Khan I., Gupta B.D., Suri K.A., Sharma S.C., Johri R.K., Sharma S.N. A simple reliable preparative high performance chromatographic technique for isolation of bioactive flavone glycoside from and extract of Cuminum cymium seeds. Acta Chromatogr. 2009, 21:499-512.
6. Gautam M., Saha S., Bani S., Kaul A., Mishra S., Patil D., Satti N.K., Suri K.A., Gairola S., Kumar S., Jadhav S., Qazi G.N., Patwardhan B. Immunomodulatory activity of Asparagus racemosus on systemic Th1/Th2 immunity: implications for immunoadjuvant potential. J. Ethnopharmacol. 2009, 121:241-247.
7. Bani S., Gautam M., Ahmad S.F., Khan B., Satti N.K., Suri K.A., Qazi G.N., Patwardhan B. Selective Th1 up-regulating activity of Withania somnifera aqueous extract in an experimental system using flow cytometry. J. Ethnopharmacol. 2006, 107:107-115.
8. Khan B., Ahmad S.F., Bani S., Kaul A., Suri K.A., Satti N.K., Athar M., Qazi G.N. Augmentation and proliferation of T lymphocytes and Th-1 cytokines by Withania somnifera in stressed mice. J. Immunopharmacol. 2006, 6:1394-1403.
9. Zorrilla E.P., Luborsky L., McKay J.R., Rosenthal R., Houldin A., Tax A., McCorkle R., Seligman D.A., Schmidt K. The relationship of depression and stressors to immunological assays: a meta-analytic review. Brain Behav. Immun. 2001, 15:199-226.
10. Borel J.F., Feurer C., Magnee C., Stahelin H. Effects of the new antilymphocytic peptide cyclosporin A in animals. J. Immunol. 1977, 32:1017-1025.
11. Reem G.H., Cook L.A., Vilcek J. Gamma interferon synthesis by human thymocytes and T lymphocytes inhibited by cyclosporine A. Science 1983, 221:63-65.
12. Szabo S.J., Dighe A.S., Gubler U., Murphy K.M. Regulation of the interleukin (IL)-12R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells. J. Exp. Med. 1997, 185:817-824.
13. Ma X., Chow J.M., Gri G., Carra G., Gerosa F., Wolf S.F., Dzialo R., Trinchieri G. The interleukin 12 p40 gene promoter is primed by interferon γ in monocytic cells. J. Exp. Med. 1996, 183:147-157.
14. + T Cells Is Sufficient to Mediate T Helper Cell Type 1 Development. J. Exp. Med 1998, 188:1651-1656.
15. Mosmann T.R., Chervinshi H., Bond M.W., Giedlin M.A., Coffman R.L. Two types of murine T cell clone I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 1986, 136:2348-2352.
16. Frick L.R., Barreiro Arcos M.L., Rapanelli M., Zappia M.P., Brocco M., Mongini C., Genaro A.M., Cremaschi G.A. Chronic restraint stress impairs T-cell immunity and promotes tumor progression in mice. Stress 2008, 1-10.
17. Krishnan N., Thellin O., Nelson D.J., Horseman B.D., Buckley A.R. Prolactin suppresses glucocorticoid-induced thymocyte apoptosis in vivo. Endocrinology 2009, 144:2102-2110.
18. Shimizu T., Kawamura T., Miyaji C., Oya H., Bannai M., Yamamoto S., Weerasinghe A., Halder R.C., Watanabe H., Hatakeyama K., Abo T. Resistance of extrathymic T cells to stress and the role of endogenous glucocorticoids in stress associated immunosuppression. J. Immunol. 2000, 51:285-292.