Transcriptome and metabolome profiling of field-grown transgenic barley lack induced differences but show cultivar-specific variances

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 14, 2010, Pages 6198-6203

  Kogel, Karl Heinz ^a   Voll, Lars M ^b   Schäfer, Patrick ^a,c   Jansen, Carin ^a,c,d   Wu, Yongchun ^c   Langen, Gregor ^a   Imani, Jafargholi ^a   Hofmann, Jörg ^b   Schmiedl, Alfred ^b   Sonnewald, Sophia ^b   Von Wettstein, Diter ^a,c   Cook, R James ^c   Sonnewald, Uwe ^b  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c WASHINGTON STATE UNIVERSITY   (United States)

^d FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

Author keywords

Chitinase; Food safety; Glucanase; Sustainability

Indexed keywords

BETA GLUCAN HYDROLASE; CHITINASE; TRANSCRIPTOME;

ALLELE; ARTICLE; BARLEY; CODON; COMPARATIVE STUDY; CULTIVAR; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; GENOTYPE; HYPOCREA LIXII; METABOLITE; METABOLOME; MYCORRHIZA; NONHUMAN; NUCLEOTIDE REPEAT; PLANT GROWTH; PLANT LEAF; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; TRANSGENE; WILD TYPE;

GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, PLANT; GLUCAN 1,3-BETA-GLUCOSIDASE; HORDEUM; METABOLOME; PLANT LEAVES; PLANTS, GENETICALLY MODIFIED;

ARBUSCULAR; FUNGI; GLOMUS; HORDEUM; HYPOCREA LIXII;

EID: 77950909162     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1001945107     Document Type: Article

References (31)

1. Cellini F, et al. (2004) Unintended effects and their detection in genetically modified crops. Food Chem Toxicol 42:1089-1125. (Pubitemid 38584592)
2. Schäfer P, et al. (2009) Manipulation of plant innate immunity and gibberellin as factor of compatibility in the mutualistic association of barley roots with Piriformospora indica. Plant J 59:461-474.
3. Fiehn O (2001) Combining genomics, metabolome analysis, and biochemical modeling to understand metabolic networks. Comp Funct Genomics 2:155-168.
4. Trethewey RN (2004) Metabolite profiling as an aid to metabolic engineering in plants. Curr Opin Plant Biol 7:196-201. (Pubitemid 38308056)
5. Gregersen PL, Brinch-Pedersen H, Holm PB (2005) A microarray-based comparative analysis of gene expression profiles during grain development in transgenic and wild type wheat. Transgenic Res 14:887-905. (Pubitemid 41706052)
6. Catchpole GS, et al. (2005) Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops. Proc Natl Acad Sci USA 102:14458-14462.
7. Kristensen C, et al. (2005) Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome. Proc Natl Acad Sci USA 102:1779-1784. (Pubitemid 40209244)
8. Baker JM, et al. (2006) A metabolomic study of substantial equivalence of field-grown genetically modified wheat. Plant Biotechnol J 4:381-392.
9. Manetti C, et al. (2006) A metabolomic study of transgenic maize (Zea mays) seeds revealed variations in osmolytes and branched amino acids. J Exp Bot 57:2613-2625. (Pubitemid 44290294)
10. Coll A, et al. (2008) Lack of repeatable differential expression patterns between MON810 and comparable commercial varieties of maize. Plant Mol Biol 68:105-117.
11. Coll A, et al. (2009) Gene expression profiles of MON810 and comparable non-GM maize varieties cultured in the field are more similar than are those of conventional lines. Transgenic Res 18:801-808.
12. Lehesranta SJ, et al. (2005) Comparison of tuber proteomes of potato varieties, landraces, and genetically modified lines. Plant Physiol 138:1690-1699.
13. Wu YC, von Wettstein D, Kannangara CG, Nirmala J, Cook RJ (2006) Growth inhibition of the cereal root pathogens Rhizoctonia solani AG8, R. oryzae and Gaeumannomyces graminis var. tritici by a recombinant endochitinase from Trichoderma harzianum. Biocontrol Sci Technol 16:631-646.
14. Cherif M, Benhamou N (1990) Cytochemical aspects of chitin breakdown during the parasitic action of a Trichoderma sp. on Fusarium oxysporum f. sp. radicis-lycopersici. Phytopathology 80:1406-1414.
15. Lorito M, et al. (1993) Chitinolytic enzymes produced by Trichoderma harzianum: Antifungal activity of purified endochitinase and chitobiosidase. Phytopathology 83:302-307.
16. Lorito M, et al. (1996) Mycoparasitic interaction relieves binding of the Cre1 carbon catabolite repressor protein to promoter sequences of the ech42 (endochitinase-encoding) gene in Trichoderma harzianum. Proc Natl Acad Sci USA 93:14868-14872. (Pubitemid 26419061)
17. Lorito M, et al. (1998) Genes from mycoparasitic fungi as a source for improving plant resistance to fungal pathogens. Proc Natl Acad Sci USA 95:7860-7865. (Pubitemid 28326031)
18. von Wettstein D (2007) From analysis of mutants to genetic engineering. Annu Rev Plant Biol 58:1-19.
19. Horvath H, et al. (2000) The production of recombinant proteins in transgenic barley grains. Proc Natl Acad Sci USA 97:1914-1919. (Pubitemid 30118543)
20. von Wettstein D, Mikhaylenko G, Froseth JA, Kannangara CG (2000) Improved barley broiler feed with transgenic malt containing heat-stable (1,3-1,4)-β-glucanase. Proc Natl Acad Sci USA 97:13512-13517.
21. von Wettstein D, Warner J, Kannangara CG (2003) Supplements of transgenic malt or grain containing (1,3-1,4)-β-glucanase to barley-based broiler diets lift their nutritive value to that of maize. Br Poult Sci 44:438-449.
22. Taylor J, Harrier LA (2003) Expression studies of plant genes differentially expressed in leaf and root tissues of tomato colonised by the arbuscular mycorrhizal fungus Glomus mosseae. Plant Mol Biol 51:619-629. (Pubitemid 36333070)
23. O'Hara RB, Brown JKM (1997) Spatial aggregation of pathotypes of barley powdery mildew. Plant Pathol 46:969-977.
24. van Wandelen C, Cohen SA (1997) Using quarternary high-performance liquid chromatography eluent systems for separating 6-aminoquinolyl-N- hydroxysuccinimidyl carbamate derivatized amino acid mixtures. J Chromatogr A 763:11-22.
25. Voll L, et al. (2003) The phenotype of the Arabidopsis cue1 mutant is not simply caused by a general restriction of the shikimate pathway. Plant J 36:301-317. (Pubitemid 37436055)
26. Abbasi AR, et al. (2009) Tocopherol deficiency in transgenic tobacco plants leads to accelerated senescence. Plant Cell Environ 32:144-157.
27. Horst RJ, et al. (2010) Ustilago maydis infection strongly alters organic nitrogen allocation in maize and stimulates productivity of systemic source leaves. Plant Physiol 152:293-308.
28. Bijlsma S, et al. (2006) Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation. Anal Chem 78:567-574. (Pubitemid 43100391)
29. Welch BL (1947) The generalization of student's problem when several different population variances are involved. Biometrika 34:28-35.
30. Eisen MB, Spellman PT, Brown PO, Botstein D (1998) Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 95:14863-14868.
31. Junker BH, Klukas C, Schreiber F (2006) VANTED: A system for advanced data analysis and visualization in the context of biological networks. BMC Bioinformatics 7:109.