Differential action of chlorinated polycyclic aromatic hydrocarbons on aryl hydrocarbon receptor-mediated signaling in breast cancer cells

Environmental Toxicology

Volumn 25, Issue 2, 2010, Pages 180-187

  Ohura, Takeshi ^a   Morita, Maki ^a   Kuruto Niwa, Ryoko ^b   Amagai, Takashi ^a   Sakakibara, Hiroyuki ^a   Shimoi, Kayoko ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b Shizuoka Eiwa Gakuin University Junior College   (Japan)

Author keywords

Aryl hydrocarbon receptor; Chlorinated polycyclic aromatic hydrocarbons; Cross talk; Cytochrome P450; Estrogen receptor

Indexed keywords

ARYL HYDROCARBON RECEPTOR; BREAST CANCER CELLS; CATHEPSIN D; CHLORINATED POLYCYCLIC AROMATIC HYDROCARBONS; CYTOCHROME P450; DOSE-DEPENDENT; ESTROGEN RECEPTOR; ESTROGEN RESPONSE ELEMENTS; GFP EXPRESSION; GREEN FLUORESCENT PROTEIN; HALOGENATED AROMATIC HYDROCARBONS; HUMAN BREAST CANCER; MCF-7 CELLS; METABOLIC ACTIVATION; REPORTER GENE; TARGET GENES; WESTERN-BLOT ANALYSIS;

AROMATIZATION; CROSSTALK; GENES; LIGANDS; ORGANIC COMPOUNDS; POLYCYCLIC AROMATIC HYDROCARBONS; SIGNALING; TRANSCRIPTION;

AROMATIC HYDROCARBONS;

3,9,10 TRICHLOROPHENANTHRENE; 6 CHLOROBENZO[A]PYRENE; AROMATIC HYDROCARBON RECEPTOR; CATHEPSIN D; CHLORINATED HYDROCARBON; CHLOROPOLYCYCLIC AROMATIC HYDROCARBON; CYTOCHROME P450 1A1; ESTRADIOL; ESTROGEN RECEPTOR; ETHOXYRESORUFIN DEETHYLASE; GREEN FLUORESCENT PROTEIN; PHENANTHRENE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON; PYRENE DERIVATIVE; UNCLASSIFIED DRUG; CYTOCHROME P 450 CYP1B1; CYTOCHROME P-450 CYP1B1; ESTROGEN RECEPTOR ALPHA; MESSENGER RNA; UNSPECIFIC MONOOXYGENASE;

CANCER; CHLORINATED HYDROCARBON; CHLORINATION; CYTOCHROME; DOSE-RESPONSE RELATIONSHIP; ESTROGENIC COMPOUND; GENE EXPRESSION; LIGAND; METABOLISM; PAH; PHENANTHRENE; RNA;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL ACTIVATION; CELL ASSAY; CHLORINATION; CONTROLLED STUDY; CYTOTOXICITY; ESTROGEN RESPONSIVE ELEMENT; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; BREAST TUMOR; CHEMISTRY; DRUG EFFECT; FEMALE; METABOLISM; POLLUTANT; TUMOR CELL LINE;

ARYL HYDROCARBON HYDROXYLASES; BREAST NEOPLASMS; CELL LINE, TUMOR; CYTOCHROME P-450 CYP1A1; ENVIRONMENTAL POLLUTANTS; ESTROGEN RECEPTOR ALPHA; FEMALE; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROCARBONS, CHLORINATED; POLYCYCLIC HYDROCARBONS, AROMATIC; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 77950903399     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20488     Document Type: Article

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