Clinicopathological significance and prognostic value of LRP16 expression in colorectal carcinoma

World Journal of Gastroenterology

Volumn 16, Issue 13, 2010, Pages 1644-1648

  Xi, Hong Qing ^a   Zhao, Po ^a   Han, Wei Dong ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Clinicopathology; Colorectal neoplasms; Immunohistochemistry; Leukemia related protein 16; Prognosis

Indexed keywords

CELL PROTEIN; LEUKEMIA RELATED PROTEIN 16; UNCLASSIFIED DRUG;

ADULT; AGED; CANCER INFILTRATION; CANCER STAGING; CLINICAL FEATURE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DISTANT METASTASIS; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROGNOSIS; PROTEIN EXPRESSION; REVIEW; SURVIVAL TIME; TUMOR VOLUME;

EID: 77950871779     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i13.1644     Document Type: Review

References (20)

1. Yu L, Han WD, Lou FD, Wang QS, Zhao Y, Caligiuri MA. Cloning of leukemia associated gene LRP16 in acute myeloid leukemia. Junyi Jinxiu Xueyuan Xuebao 2000; 21: 81-84.
2. Han WD, Yu L, Lou FD, Wang QS, Zhao Y, Shi ZJ, Jiao HY, Zhou JJ. Cloning and Expression Characterization of the Full Length cDNA for a Novel Leukemia-associated Gene LRP16. Zhongguo Shengwu Huaxue Yu Fenzi Shengwu Xuebao 2001; 17: 209-214.
3. Han WD, Lou FD, Yu L, Wang QS, Han XP, Li JX. SAGE pattern of LRP16 gene and its expression in normal blood and leukemic cells. Junyi Jinxiu Xueyuan Xuebao 2002; 23: 161-163.
4. Han WD, Mu YM, Lu XC, Xu ZM, Li JX, Yu L, Song HJ, Li M, Lu JM, Pan CY. Estrogen stimulates human breast cancer MCF-7 cell proliferation by up-regulation of LRP16 mRNA via activation of estrogen receptor-alpha. Zhonghua Neifenmi Daixie Zazhi 2004; 20: 165-168.
5. Han WD, Mu YM, Lu XC, Xu ZM, Li XJ, Yu L, Song HJ, Li M, Lu JM, Zhao YL, Pan CY. Up-regulation of LRP16 mRNA by 17beta-estradiol through activation of estrogen receptor alpha (ERalpha), but not ERbeta, and promotion of human breast cancer MCF-7 cell proliferation: a preliminary report. Endocr Relat Cancer 2003; 10: 217-224.
6. Li YZ, Zhao P, Han WD. Clinicopathological significance of LRP16 protein in 336 gastric carcinoma patients. World J Gastroenterol 2009; 15: 4833-4837.
7. Compton CC. Colorectal carcinoma: diagnostic, prognostic, and molecular features. Mod Pathol 2003; 16: 376-388.
8. Jiang H, Teng R, Wang Q, Zhang X, Wang H, Wang Z, Cao J, Teng L. Transcriptional analysis of estrogen receptor alpha variant mRNAs in colorectal cancers and their matched nor- mal colorectal tissues. J Steroid Biochem Mol Biol 2008; 112: 20-24.
9. Di Leo A, Messa C, Cavallini A, Linsalata M. Estrogens and colorectal cancer. Curr Drug Targets Immune Endocr Metabol Disord 2001; 1: 1-12.
10. Zhou ZW, Wan DS, Wang GQ, Pan ZZ, Lu HP, Gao JH, Ding PR. [Expression of estrogen receptor and progesterone receptor in colorectal cancer: a quantitative study] Ai Zheng 2004; 23: 851-854.
11. Han WD, Zhao YL, Meng YG, Zang L, Wu ZQ, Li Q, Si YL, Huang K, Ba JM, Morinaga H, Nomura M, Mu YM. Estrogenically regulated LRP16 interacts with estrogen receptor alpha and enhances the receptor's transcriptional activity. Endocr Relat Cancer 2007; 14: 741-753.
12. Han WD, Zhao YL, Li Q, Mu YM, Li X, Song HJ, Lu ZQ. Inhibition of proliferation of human breast cancer MCF-7 cells by small interference RNA against LRP16 gene. Chin J Cancer Res 2004; 16: 239-245.
13. Han WD, Yang D, Li Q, Zhao XL, Ma L, Mu YM. Improvement of radiation sensitivity by inhibiting expression of the human LRP16 gene in tumor cells. Junyi Jinxiu Xueyuan Xuebao 2005; 26: 183-185.
14. Zhao YL, Han WD, Li Q, Mu YM, Lu XC, Yu L, Song HJ, Li X, Lu JM, Pan CY. Mechanism of transcriptional regulation of LRP16 gene expression by 17-beta estradiol in MCF-7 hu- man breast cancer cells. J Mol Endocrinol 2005; 34: 77-89.
15. Lu XC, Lou FD, Han WD, Zhu XD, Mu YM, Xu ZM, Yu L. [Analysis of LRP16 gene promoter activity] Zhongguo Shiyan Xueyexue Zazhi 2006; 14: 146-149.
16. Liao DX, Han WD, Zhao YL, Pu YD, Mu YM, Luo CH, Li XH. [Expression and clinical significance of LRP16 gene in human breast cancer] Ai Zheng 2006; 25: 866-870.
17. Gerits N, Kostenko S, Moens U. In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice. Transgenic Res 2007; 16: 281-314.
18. Morissette M, Jourdain S, Al Sweidi S, Menniti FS, Ramirez AD, Di Paolo T. Role of estrogen receptors in neuroprotec- tion by estradiol against MPTP toxicity. Neuropharmacology 2007; 52: 1509-1520.
19. Zaitsu M, Narita S, Lambert KC, Grady JJ, Estes DM, Curran EM, Brooks EG, Watson CS, Goldblum RM, Midoro-Horiuti T. Estradiol activates mast cells via a non-genomic estrogen receptor-alpha and calcium influx. Mol Immunol 2007; 44: 1977-1985.
20. Morales LB, Loo KK, Liu HB, Peterson C, Tiwari-Woodruff S, Voskuhl RR. Treatment with an estrogen receptor alpha ligand is neuroprotective in experimental autoimmune encephalomyelitis. J Neurosci 2006; 26: 6823-6833