Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 9, 2010, Pages 2790-2796

  Wang, Ping ^a   Ownby, Stacy ^a   Zhang, Zhizhen ^a   Yuan, Wei ^a   Li, Shiyou ^a  

^a STEPHEN F AUSTIN STATE UNIVERSITY   (United States)

Author keywords

Cytotoxicity; Structure activity relationship; Topoisomerase I; Triterpenoid glycosides; Triterpenoids

Indexed keywords

AESCULIOSIDE; DNA TOPOISOMERASE; POLYHYDROXYLOLEANANE; POLYHYDROXYLTERPENOID; TRITERPENOID; TRITERPENOID GLYCOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYTOTOXICITY; DRUG BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; HYDROLYSIS; STRUCTURE ACTIVITY RELATION;

AESCULUS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE I; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; GLYCOSIDES; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES;

AESCULUS PAVIA;

EID: 77950866191     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.03.063     Document Type: Article

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