Dammarenolic acid, a secodammarane triterpenoid from Aglaia sp. shows potent anti-retroviral activity in vitro

Phytomedicine

Volumn 17, Issue 7, 2010, Pages 540-547

  Esimone, Charles O ^a,c,d   Eck, Gero ^b   Nworu, Chukwuemeka S ^a,c   Hoffmann, Dennis ^a   Überla, Klaus ^a   Proksch, Peter ^b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY OF NIGERIA   (Nigeria)

^d NNAMDI AZIKIWE UNIVERSITY   (Nigeria)

Author keywords

Aglaia; Anti retroviral; Dammarenolic acid; Nevirapine; Secodammarane; Triterpenoid

Indexed keywords

APHIDICOLIN; DAMMARENOLIC ACID; NEVIRAPINE; TRITERPENOID; UNCLASSIFIED DRUG; VIRUS VECTOR;

AGLAIA; ANTIVIRAL ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRAIN HEK293; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IC 50; IN VITRO STUDY; KINETICS; LENTIVIRINAE; LUNG CARCINOMA; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; SCREENING; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS REPLICATION;

AGLAIA; ANIMALS; ANTI-RETROVIRAL AGENTS; CELL CYCLE; CELL PROLIFERATION; CYTOTOXINS; ESTERS; HAPLORHINI; HELA CELLS; HIV INFECTIONS; HIV-1; HUMANS; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NEVIRAPINE; PHYTOTHERAPY; PLANT BARK; PLANT EXTRACTS; RETROVIRIDAE; SIMIAN IMMUNODEFICIENCY VIRUS; TRITERPENES;

AGLAIA; HUMAN IMMUNODEFICIENCY VIRUS 1; MELIACEAE; MURINE LEUKEMIA VIRUS; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 77950865632     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2009.10.015     Document Type: Article

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