Identification of benzimidazole-based inhibitors of the mitogen activated kinase-5 signaling pathway

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 9, 2010, Pages 2892-2896

  Flaherty, Patrick T ^a   Chopra, Ishveen ^a   Jain, Prashi ^a   Yi, Shuyan ^a   Allen, Erika ^a   Cavanaugh, Jane ^a  

^a DUQUESNE UNIVERSITY   (United States)

Author keywords

Benzimidazole; ERK5; Inhibitor; MEK5

Indexed keywords

BENZIMIDAZOLE DERIVATIVE; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR;

ARTICLE; CELL CULTURE; DRUG ACTIVITY; DRUG IDENTIFICATION; DRUG STRUCTURE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

BENZIMIDAZOLES; CELL LINE; EPIDERMAL GROWTH FACTOR; HUMANS; MAP KINASE KINASE 5; MITOGEN-ACTIVATED PROTEIN KINASE 7; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; SIGNAL TRANSDUCTION;

EID: 77950858349     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.03.033     Document Type: Article

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