Effects of genistein on β-catenin signaling and subcellular distribution of actin-binding proteins in human umbilical CD105-positive stromal cells

Journal of Cellular Physiology

Volumn 223, Issue 2, 2010, Pages 423-434

  Shieh, Dar Bin ^a   Li, Rui You ^b   Liao, Jiuan Miaw ^b   Chen, Gin Den ^c   Liou, Ying Ming ^b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; BETA CATENIN; CALCIUM ION; CALDESMON; CYCLIN D1; ENDOGLIN; FORMIN 2; GENISTEIN; MESSENGER RNA; PROFILIN; TROPOMYOSIN; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; NEWBORN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; STROMA CELL; UMBILICAL CORD;

ANTIGENS, CD; BETA CATENIN; BIOLOGICAL MARKERS; CALCIUM SIGNALING; CALMODULIN-BINDING PROTEINS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D1; CYTOPLASM; GENISTEIN; HUMANS; INFANT, NEWBORN; MESENCHYMAL STEM CELLS; MICROFILAMENT PROTEINS; NERVE TISSUE PROTEINS; PROFILINS; PROTEIN ISOFORMS; PROTEIN KINASE INHIBITORS; RECEPTORS, CELL SURFACE; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; STROMAL CELLS; TROPOMYOSIN; UMBILICAL CORD;

EID: 77950855926     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22051     Document Type: Article

References (67)

1. Akiyama T, Ogawara H. 1991. Use and specificity of genistein as inhibitor of protein-tyrosine kinases. Methods Enzymol 201:362-370.
2. Akiyama T, Ishida J, Nakagawa S, Ogawara H, Watanabe S, Itoh N, Shibuya M, Fukami Y. 1987. Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262:5592-5595.
3. Andl CD, Rustgi AK. 2005. No one-way street: Cross-talk between e-cadherin and receptor tyrosine kinase (RTK) signaling: A mechanism to regulate RTK activity. Cancer Bio Ther 4:28-31.
4. Annerén C. 2008. Tyrosine kinase signalling in embryonic stem cells. Clin Sci (Lond) 115:43-55. (Pubitemid 351930792)
5. Bach CT, Creed S, Zhong J, Mahmassani M, Schevzov G, Stehn J, Cowell LN, Naumanen P, Lappalainen P, Gunning PW, O'Neill GM. 2009. Tropomyosin isoform expression regulates the transition of adhesions to determine cell speed and direction. Mol Cell Biol 29:1506-1514.
6. Basu R, Chang F. 2007. Shaping the actin cytoskeleton usingmicrotubule tips. Curr Opin Cell Biol 19:88-94. (Pubitemid 46123976)
7. Bershadsky A. 2004. Magic touch:Howdoes cell - cell adhesion trigger actin assembly? Trends Cell Biol 14:589-593.
8. Bharadwaj S, Prasad GL. 2002. Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells. Cancer Lett 183:205-213. (Pubitemid 34628425)
9. Blume-Jensen P, Hunter T. 2001. Oncogenic kinase signalling. Nature 411:355-365.
10. Can A, Karahuseyinoglu S. 2007. Human umbilical cord stroma with regard to the source of fetus-derived stem cells. Stem Cells 25:2886-2895. (Pubitemid 350127873)
11. Chhabra ES, Higgs HN. 2007. The many faces of actin:Matching assembly factors with cellular structures. Nat Cell Biol 9:1110-1121.
12. Daugherty RL, Gottardi CJ. 2007. Phospho-regulation of beta-catenin adhesion and signaling functions. Physiology 22:303-309.
13. Dave B, Eason RR, Till SR, Geng Y, Velarde MC, Badger TM, Simmen RC. 2005. The soy isoflavone genistein promotes apoptosis in mammary epithelial cells by inducing the tumor suppressor PTEN. Carcinogenesis 26:1793-1803. (Pubitemid 41487996)
14. Dohn MR, Brown MV, Reynolds AB. 2009. An essential role for p120-catenin in Src- and Rac1-mediated anchorage-independent cell growth. J Cell Biol 184:437-450.
15. Dumont J, Million K, Sunderland K, Rassinier P, Lim H, Leader B, Verlhac MH. 2007. Formin-2 is required for spindlemigration and for the late steps of cytokinesis in mouse oocytes. Dev Biol 301:254-265. (Pubitemid 46001380)
16. El Touny LH, Banerjee PP, 2007. Akt GSK-3 pathway as a target in genistein-induced inhibition of TRAMP prostate cancer progression toward a poorly differentiated phenotype. Carcinogenesis 28:1710-1717.
17. Eppinga RD, Li Y, Lin JL, Lin JJ. 2006. Tropomyosin and caldesmon regulate cytokinesis speed and membrane stability during cell division. Arch Biochem Biophys 456:161-174. (Pubitemid 44880284)
18. Fotsis T, Pepper M, Adlercreutz H, Fleischmann G, Hase T, Montesano R, Schweigerer L. 1993. Genistein, a dietary-derived inhibitor of in vitro angiogenesis. Proc Natl Acad Sci USA 90:2690-2694. (Pubitemid 23113482)
19. Frame MC. 2004. Newest findings on the oldest oncogene; how activated src does it. J Cell Sci 117:989-998.
20. Fu YS, Cheng YC, Lin MY, Cheng H, Chu PM, Chou SC, Shih YH, Ko MH, Sung MS. 2006. Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: Potential therapeutic application for Parkinsonism. Stem Cells 24:115-124.
21. Goode BL, Eck MJ. 2007. Mechanism and function of formins in the control of actin assembly. Annu Rev Biochem 76:593-627.
22. Greenberg MJ, Wang CL, Lehman W, Moore JR. 2008. Modulation of actin mechanics by caldesmon and tropomyosin. Cell Motil Cytoskeleton 65:156-164. (Pubitemid 351272976)
23. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
24. Gunning P, Schevzov G, Kee AJ, Hardeman EC. 2005. Tropomyosin isoforms: Divining rods for actin cytoskeleton function. Trends Cell Biol 15:333-341. (Pubitemid 40805330)
25. Gunning P, O'Neill G, Hardeman E. 2008. Tropomyosin-based regulation of the actin cytoskeleton in time and space. Physiol Rev 88:1-35.
26. Huelsken J, Birchmeier W. 2001. New aspects of Wnt signaling pathways in higher vertebrates. Curr Opin Genet Dev 11:547-553. (Pubitemid 32800729)
27. Humphrey MB, Herrera-Sosa H, Gonzalez G, Lee R, Bryan J. 1992. Cloning of cDNAs encoding human caldesmons. Gene 112:197-204.
28. Ishikawa R, Yamashiro S, Matsumura F. 1989. Differential modulation of actin-severing activity of gelsolin by multiple isoforms of cultured rat cell tropomyosin. Potentiation of protective ability of tropomyosins by 83-kDa nonmuscle caldesmon. J Biol Chem 264:7490-7497. (Pubitemid 19119165)
29. Jagadeesh S, Kyo S, Banerjee PP. 2006. Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells. Cancer Res 66:2107-2115.
30. Kaplan KB, Swedlow JR, Varmus HE, Morgan DO. 1992. Association of p60c-src with endosomal membranes in mammalian fibroblasts. J Cell Biol 118:321-333.
31. Kaplan KB, Bibbins KB, Swedlow JR, Arnaud M, Morgan DO, Varmus HE. 1994. Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. EMBO J 13:4745-4756.
32. Leader B, Leder P. 2000. Formin-2, a novel formin homology protein of the cappuccino subfamily, is highly expressed in the developing and adult central nervous system. Mech Dev 93:221-231.
33. Leader B, Lim H, Carabatsos MJ, Harrington A, Ecsedy J, Pellman D, Maas R, Leder P. 2002. Formin-2, polyploidy, hypofertility and positioning of themeiotic spindle in mouse oocytes. Nat Cell Biol 4:921-928.
34. Lee YH, Gallant C, Guo H, Li Y, Wang CLA, Morgan KG. 2000. Regulation of vascular smooth muscle tone by N-terminal region of caldesmon: Possible role of tethering actin to myosin. J Biol Chem 275:3213-3220.
35. Li Y, Sarkar FH. 2002. Inhibition of nuclear factor κB activation in PC3 cells by genistein is mediated via Akt signaling pathway. Clin Cancer Res 8:2369-2377.
36. Li Y, Zhuang S, Guo H, Mabuchi K, Lu RC, Wang CA. 2000. The major myosin-binding site of caldesmon resides near its N-terminal extreme. J Biol Chem 275:10989-10994.
37. Li Y, Lin JL, Reiter RS, Daniels K, Soll DR, Lin JJ. 2004. Caldesmon mutant defective in Ca(2+)-calmodulin binding interferes with assembly of stress fibers and affects cell morphology, growth and motility. J Cell Sci 117:3593-3604.
38. Li Y, Liu L, Andrews LG, Tollefsbol TO. 2009. Genistein depletes telomerase activity through cross-talk between genetic and epigenetic mechanisms. Int J Cancer 125:286-296.
39. Liao QC, Li YL, Qin YF, Quarles LD, Xu KK, Li R, Zhou HH, Xiao ZS. 2008. Inhibition of adipocyte differentiation by phytoestrogen genistein through a potential downregulation of extracellular signal-regulated kinases 1/2 activity. J Cell Biochem 104:1853-1864.
40. Lilien J, Balsamo J. 2005. The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of beta-catenin. Curr Opin Cell Biol 17:459-465.
41. Lillehoj EP, Lu W, Kiser T, Goldblum SE, Kim KC. 2007. MUC1 inhibits cell proliferation by a beta-catenin-dependent mechanism. Biochim Biophys Acta 1773:1028-1038.
42. Liou YM, Chang LY, Liaw JM, Jiang MJ. 2005. Osteopontin gene expression in the aorta and the heart of propylthiouracil-induced hypothyroid mice. J Biomed Sci 12:869-880.
43. Liou YM, Watanabe M, Yumoto M, Ishiwata S. 2009. Regulatory mechanism of smooth muscle contraction studied with gelsolin-treated strips of taenia caeci in guinea pig. Am J Physiol Cell Physiol 296:C1024-C1033.
44. Moissoglu K, Gelman IH. 2003. v-Src rescues actin-based cytoskeletal architecture and cell motility and induces enhanced anchorage independence during oncogenic transformation of focal adhesion kinase-null fibroblasts. J Biol Chem 278:47946-47959.
45. Okura A, Arakawa H, Oka H, Yoshinari T, Monden Y. 1988. Effect of genistein on topoisomerase activity and on the growth of [Val12]Ha-ras- transformed NIH 3T3 cells. Biochem Biophys Res Commun 157:183-189.
46. Perry SV. 2001. Vertebrate tropomyosin: Distribution, properties and function. J Muscle Res Cell Motil 22:5-49.
47. Phillips GN Jr, Lattman EE, Cummins P, Lee KY, Cohen C. 1979. Crystal structure and molecular interactions of tropomyosin. Nature 278:413-417.
48. Pollard TD. 2007. Regulation of actin filament assembly by Arp2/3 complex and formins. Annu Rev Biophys Biomol Struct 36:451-477.
49. Romero S, Le Clainche C, Didry D, Egile C, Pantaloni D, Carlier MF. 2004. Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis. Cell 119:419-429.
50. Romero S, Didry D, Larquet E, Boisset N, Pantaloni D, Carlier MF. 2007. How ATP hydrolysis controls filament assembly from profilin-actin: Implication for formin processivity. J Biol Chem 282:8435-8445.
51. Roy PG, Thompson AM. 2006. Cyclin D1 and breast cancer. Breast 15:718-727.
52. Ryley DA, Wu HH, Leader B, Zimon A, Reindollar RH, Gray MR. 2005. Characterization and mutation analysis of the human formin-2 (FMN2) gene in women with unexplained infertility. Fertil Steril 83:1363-1371.
53. Sakla MS, Shenouda NS, Ansell PJ, Macdonald RS, Lubahn DB. 2007. Genistein affects HER2 protein concentration, activation, and promoter regulation in BT-474 human breast cancer cells. Endocrine 32:69-78.
54. Schlessinger J. 2000.Newroles for Src kinases in control of cell survival and angiogenesis. Cell 100:293-296. (Pubitemid 30353084)
55. Schlessinger J. 2001. Cell signaling by receptor tyrosine kinases. Cell 103:211-225.
56. Schuh M, Ellenberg J. 2008. A new model for asymmetric spindle positioning in mouse oocytes. Curr Biol 18:1986-1992.
57. Secco M, Zucconi E, Vieira NM, Fogaça LL, Cerqueira A, Carvalho MD, Jazedje T, Okamoto OK, Muotri AR, Zatz M. 2008. Multipotent stem cells from umbilical cord: Cord is richer than blood! Stem Cells 26:146-150.
58. Shen K, Hines AC, Schwarzer D, Pickin KA, Cole PA. 2005. Protein kinase structure and function analysis with chemical tools. Biochim Biophys Acta 1754:65-78. (Pubitemid 41797688)
59. Shon YH, Park SD, Nam KS. 2006. Effective chemopreventive activity of genistein against human breast cancer cells. J Biochem Mol Biol 9:448-451. (Pubitemid 44371875)
60. Sobue K, Muramoto Y, Fujita M, Kakiuchi S. 1981. Purification of a calmodulin-binding protein from chicken gizzard that interacts with F-actin. Proc Natl Acad Sci USA 78:5652-5655. (Pubitemid 12245208)
61. Takahashi-Yanaga F, Sasaguri T. 2008. GSK-3beta regulates cyclin D1 expression: A new target for chemotherapy. Cell Signal 20:581-589. (Pubitemid 351241128)
62. Troyer DL, Weiss ML. 2008. Wharton's jelly-derived cells are a primitive stromal cell population. Stem Cells 26:591-599.
63. Wang HS, Hung SC, Peng ST, Huang CC, Wei HM, Guo YJ, Fu YS, Lai MC, Chen CC. 2004. Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. Stem Cells 22:1330-1337. (Pubitemid 39636408)
64. Wawro B, Greenfield NJ, Wear MA, Cooper JA, Higgs HN, Hitchcock-DeGregori SE. 2007. Tropomyosin regulates elongation by formin at the fast-growing end of the actin filament. Biochemistry 46:8146-8155. (Pubitemid 47051650)
65. Welham MJ, Wyke JA. 1988. A single point mutation has pleiotropic effects on pp60(v-src) function. J Virol 62:1898-1906.
66. Yamashiro S, Yamakita Y, Ishikawa R, Matsumura F. 1990. Mitosis-specific phosphorylation causes 83K non-muscle caldesmon to dissociate from microfilaments. Nature 344:675-678. (Pubitemid 20108371)
67. Zwiller J, Sassone-Corsi P, Kakazu K, Boynton AL. 1991. Inhibition of PDGF-induced c-jun and c-fos expression by a tyrosine protein kinase inhibitor. Oncogene 6:219-221. (Pubitemid 21902666)