Effect of radio-frequency electromagnetic radiations (RF-EMR) on passive avoidance behaviour and hippocampal morphology in Wistar rats

Upsala Journal of Medical Sciences

Volumn 115, Issue 2, 2010, Pages 91-96

  Narayanan, Sareesh Naduvil ^a   Kumar, Raju Suresh ^a   Potu, Bhagath Kumar ^b   Nayak, Satheesha ^a   Bhat, P Gopalakrishna ^b   Mailankot, Maneesh ^a  

^a MELAKA MANIPAL MEDICAL COLLEGE   (India)

^b KASTURBA MEDICAL COLLEGE   (India)

Author keywords

Hippocampus; Memory; Mobile phone; Passive avoidance; RF EMR (radio frequency electromagnetic radiation)

Indexed keywords

ANIMAL; ARTICLE; AVOIDANCE BEHAVIOR; ELECTROMAGNETIC FIELD; HIPPOCAMPUS; HISTOLOGY; MALE; MOBILE PHONE; RADIATION EXPOSURE; RADIOFREQUENCY RADIATION; RAT; WISTAR RAT;

ANIMALS; AVOIDANCE LEARNING; CELLULAR PHONE; ELECTROMAGNETIC FIELDS; HIPPOCAMPUS; MALE; RADIO WAVES; RATS; RATS, WISTAR;

EID: 77950835387     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: 10.3109/03009730903552661     Document Type: Article

References (29)

1. Finnie JW, Blumbergs PC, Manavis J, Utteridge TD, Gebski V, Davies RA, et al. Effect of long-term mobile communication microwave exposure on vascular permeability in mouse brain. Pathology. 2004;36:96-97 (Pubitemid 34827997)
2. Aalto S, Haarala C, Brück A, Sipilä H, Hämälä inen H, Rinne JO. Mobile phone affects cerebral blood flow in humans. J Cereb Blood Flow Metab. 2006;26:885-890 (Pubitemid 43980404)
3. Kolesnyk IuM, Zhulins'kyǐ VO, Abramov AV, Kalinichenko MA. Effect of mobile phone electromagnetic emission on characteristics of cerebral blood circulation and neurohumoral regulation in humans. Fiziol Zh. 2008;54:90-93
4. Finnie JW, Blumbergs PC, Cai Z, Manavis J, Kuchel TR. Effect of mobile telephony on blood-brain barrier permeability in the fetal mouse brain. Pathology. 2006;38:63-65 (Pubitemid 43259256)
5. Irmak MK, Fadillioǧlu E, Güleç M, Erdoǧan H, Yaǧmurca M, Akyol O. Effects of electromagnetic radiation from a cellular telephone on the oxidant and antioxidant levels in rats. Cell Biochem Funct. 2002;20:279-283 (Pubitemid 35340062)
6. Tamasidze AG, Nikolaishvili MI. Effect of high-frequency EMF on public health and its neuro-chemical investigations. Georgian Med News. 2007:58-60.
7. Salford LG, Brun AE, Eberhardt JL, Malmgren L, Bertil R. Nerve cell damage in mammalian brain after exposure to microwaves from GSM mobile phones. Environ Health Perspect. 2003;111:881-883 (Pubitemid 36790379)
8. Lai H, Singh NP. Single and double-stranded DNA breaks in rat brain cells after acute exposure to radiofrequency electromagnetic radiation. Int J Radiat Biol. 1996;69:513-521 (Pubitemid 26156821)
9. Narayanan SN, Kumar RS, Potu BK, Nayak S, Mailankot M. Spatial memory performance of Wistar rats exposed to mobile phone. Clinics. 2009;64:231-234
10. Bures J, Buresova O, Huston JP. Techniques and basic experiments for the study of brain and behavior. 2nd revised and enlarged ed. Amsterdam, New York: Elsevier Science Publishers; 1983. p. 148.
11. Bartus RT, Dean RL, Goas JA, Lippa AS. Age-related changes in passive avoidance retention: modulation with dietary choline. Science. 1980;209:301-303
12. Glick SD, Crane AM, Barker LA, Mittag TW. Effect of N-hydroxyl- pyrrolidinum methiodide, a choline analogue, on passive avoidance behaviour in mice. Neuropharmacology. 1975;14:561-564
13. Kopf SR, Buchholzer ML, Hilgert M, Löffelholz K, Klein J. Glucose plus choline improve passive avoidance behaviour and increase hippocampal acetylcholine release in mice. Neuroscience. 2001;103:365-371 (Pubitemid 32201923)
14. Patterson CM, Kosson DS, Newman JP. Reaction to punishment, reflectivity, and passive avoidance learning in extraverts. J Pers Soc Psychol. 1987;52:565-575
15. Liu X, Yang D, Meng Z. The effects of SO2 on electric activity learning and memory of rat hippocampal neurons. Wei Sheng Yan Jiu. 2008;37:660-663
16. Zola-Morgan SM, Squire LR. The primate hippocampal formation: evidence for a time-limited role in memory storage. Science. 1990;250:288-290 [My paper]. (Pubitemid 20354237)
17. Stubley-Weatherly L, Harding JW, Wright JW. Effects of discrete kainic acid-induced hippocampal lesions on spatial and contextual learning and memory in rats. Brain Res. 1996;716:29-38. (Pubitemid 26156598)
18. Sandi C, Rose SP, Patterson TA. Unilateral hippocampal lesions prevent recall of a passive avoidance task in day-old chicks. Neurosci Lett. 1992;141:255-258
19. Sokolovic D, Djindjic B, Nikolic J, Bjelakovic G, Pavlovic D, Kocic G, et al. Melatonin reduces oxidative stress induced by chronic exposure of microwave radiation from mobile phones in rat brain. J Radiat Res (Tokyo). 2008; 49:579-586
20. Meral I, Mert H, Mert N, Deger Y, Yoruk I, Yetkin A, et al. Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress and some vitamin levels of guinea pigs. Brain Res. 2007;1169:120-124 (Pubitemid 47374099)
21. Ilhan A, Gurel A, Armutcu F, Kamisli S, Iraz M, Akyol O, et al. Ginkgo biloba prevents mobile phone-induced oxidative stress in rat brain. Clin Chim Acta. 2003;111:881-883
22. Yan JG, Agresti M, Zhang LL, Yan Y, Matloub HS. Upregulation of specific mRNA levels in rat brain after cell phone exposure. Electromagn Biol Med. 2008;27:147-154 (Pubitemid 351913224)
23. Zhao TY, Zou SP, Knapp PE. Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes. Neurosci Lett. 2007;412:34-38
24. Joubert V, Bouthoumieu S, Leveque P, Yardin C. Apoptosis is induced by radiofrequency fields through the caspaseindependent mitochondrial pathway in cortical neurons. Radiat Res. 2008;169:38-45. (Pubitemid 351295091)
25. Laming PR, Kimelberg H, Robinson S, Salm A, Hawrylak N, Müller C, et al. Neuronal-glial interactions and behaviour. Neurosci Biobehav Rev. 2000;24:295-340. (Pubitemid 30227249)
26. Laming PR. Do glia contribute to behaviour? A neuromodulatory review. Comp Biochem Physiol A. 1989; 94:555-568
27. Brillaud E, Piotrowski A, de Seze R. Effect of an acute 900MHz GSM exposure on glia in the rat brain: a timedependent study. Toxicology. 2007;238:23-33. (Pubitemid 47088045)
28. Ammari M, Brillaud E, Gamez C, Lecomte A, Sakly M, Abdelmelek H, et al. Effect of a chronic GSM 900 MHz exposure on glia in the rat brain. Biomed Pharmacother. 2008;62:273-281 (Pubitemid 351626449)
29. Richter-Levin G, Akirav I. Amygdala-hippocampus dynamic interaction in relation to memory. Mol Neurobiol. 2000; 22:11-20. (Pubitemid 32545339)