메뉴 건너뛰기




Volumn 62, Issue 1, 2010, Pages 86-94

Does nebivolol influence serum concentrations of proinflammatory cytokines in hypertensive (SHR) and normotensive (WKY) rats?

Author keywords

LPS; Nebivolol; Proinflammatory cytokines; SHR; WKY

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NEBIVOLOL; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 77950833511     PISSN: 22995684     EISSN: 22995684     Source Type: Journal    
DOI: 10.1016/S1734-1140(10)70245-0     Document Type: Article
Times cited : (8)

References (37)
  • 1
    • 34249879247 scopus 로고    scopus 로고
    • Metabolic profile of nebivolol, a β-adrenoceptor antagonist with unique characteristics
    • Agabiti Rosei E, Rizzoni D: Metabolic profile of nebivolol, a β-adrenoceptor antagonist with unique characteristics. Drugs, 2007, 67, 1097-1107.
    • (2007) Drugs , vol.67 , pp. 1097-1107
    • Agabiti Rosei, E.1    Rizzoni, D.2
  • 2
    • 33751016810 scopus 로고    scopus 로고
    • Influence of amlodipine and atenolol on lipopolysaccharide (LPS)-induced serum concentrations of TNF-α, IL-1β, IL-6 in spontaneously hypertensive rats (SHR)
    • Andrzejczak D, Górska D, Czarnecka E: Influence of amlodipine and atenolol on lipopolysaccharide (LPS)-induced serum concentrations of TNF-α, IL-1β, IL-6 in spontaneously hypertensive rats (SHR). Pharmacol Rep, 2006,58,711-719.
    • (2006) Pharmacol Rep , vol.58 , pp. 711-719
    • Andrzejczak, D.1    Górska, D.2    Czarnecka, E.3
  • 3
    • 38049126187 scopus 로고    scopus 로고
    • Influence of hypotensive drugs on lipopolysaccharide (LPS)-induced serum concentrations of tumor necrosis factor alpha (TNF-α), interleukin (IL)-1β, IL-6 in spontaneously hypertensive rats (SHR)
    • Andrzejczak D, Górska, D, Czarnecka E: Influence of hypotensive drugs on lipopolysaccharide (LPS)-induced serum concentrations of tumor necrosis factor alpha (TNF-α), interleukin (IL)-1β, IL-6 in spontaneously hypertensive rats (SHR). Pharmacol Rep, 2007, Suppl 1, 59,183-191.
    • (2007) Pharmacol Rep , vol.59 , Issue.SUPPL. 1 , pp. 183-191
    • Andrzejczak, D.1    Górska, D.2    Czarnecka, E.3
  • 4
    • 13544259939 scopus 로고    scopus 로고
    • Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-α) and essential hypertension
    • Bautista LE, Vera LM, Arenas IA, Gamarra G: Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-α) and essential hypertension. J Hum Hypertens, 2005, 19, 149-154.
    • (2005) J Hum Hypertens , vol.19 , pp. 149-154
    • Bautista, L.E.1    Vera, L.M.2    Arenas, I.A.3    Gamarra, G.4
  • 5
    • 0030671491 scopus 로고    scopus 로고
    • Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo
    • Bhagat K, Vallance P: Inflammatory cytokines impair endothelium-dependent dilatation in human veins in vivo. Circulation, 1997, 96, 3042-3047.
    • (1997) Circulation , vol.96 , pp. 3042-3047
    • Bhagat, K.1    Vallance, P.2
  • 6
    • 0031106185 scopus 로고    scopus 로고
    • Increased serum levels of interleukin-1β in the systemic circulation of patients with essential hypertension: Additional risk factor for atherogenesis in hypertensive patients?
    • Dalekos GN, Elisaf M, Bairaktari E, Tsolas O, Siamopoulos KC: Increased serum levels of interleukin-1β in the systemic circulation of patients with essential hypertension: additional risk factor for atherogenesis in hypertensive patients? J Lab Clin Med, 1997, 129, 300-308.
    • (1997) J Lab Clin Med , vol.129 , pp. 300-308
    • Dalekos, G.N.1    Elisaf, M.2    Bairaktari, E.3    Tsolas, O.4    Siamopoulos, K.C.5
  • 8
    • 0032842901 scopus 로고    scopus 로고
    • Differen-tial effect of a single high dose of the tricyclic antide-pressant imipramine on interleukin-1β and tumor necrosis factor-α secretion following an in vivo lipopolysac-charide challenge in rats
    • Dredge K, Connor TJ, Kelly JP, Leonard BE: Differen-tial effect of a single high dose of the tricyclic antide-pressant imipramine on interleukin-1β and tumor necrosis factor-α secretion following an in vivo lipopolysac-charide challenge in rats. Int J Immunopharmacol, 1999, 21,663-673.
    • (1999) Int J Immunopharmacol , vol.21 , pp. 663-673
    • Dredge, K.1    Connor, T.J.2    Kelly, J.P.3    Leonard, B.E.4
  • 9
    • 0027098040 scopus 로고
    • Endo-toxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: Low doses stimulate he-patic triglyceride production while high doses inhibit clearance
    • Feingold KR, Staprans I, Memon RA, Moser AH, Shigenaga JK, Doerrler W, Dinarello CA et al.: Endo-toxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate he-patic triglyceride production while high doses inhibit clearance. J Lipid Res, 1992, 33, 1765-1776.
    • (1992) J Lipid Res , vol.33 , pp. 1765-1776
    • Feingold, K.R.1    Staprans, I.2    Memon, R.A.3    Moser, A.H.4    Shigenaga, J.K.5    Doerrler, W.6    Dinarello, C.A.7
  • 10
    • 54249115381 scopus 로고    scopus 로고
    • Nebivolol re-duces experimentally induced warm renal ischemia reperfusion injury in rats
    • Gandhi C, Zalawadia R, Balaraman R: Nebivolol re-duces experimentally induced warm renal ischemia reperfusion injury in rats. Ren Fail, 2008, 30, 921-930.
    • (2008) Ren Fail , vol.30 , pp. 921-930
    • Gandhi, C.1    Zalawadia, R.2    Balaraman, R.3
  • 11
    • 44949090646 scopus 로고    scopus 로고
    • Effects of ne-bivolol on endothelial gene expression during oxidative stress in human umbilical vein endothelial cells
    • Garbin U, Fratta Pasini A, Stranieri C, Manfro S, Mozzini C, Boccioletti V, Pasini A et al.: Effects of ne-bivolol on endothelial gene expression during oxidative stress in human umbilical vein endothelial cells. Mediators Inflamm, 2008, 2008, 367-590.
    • (2008) Mediators Inflamm , vol.2008 , pp. 367-590
    • Garbin, U.1    Fratta Pasini, A.2    Stranieri, C.3    Manfro, S.4    Mozzini, C.5    Boccioletti, V.6    Pasini, A.7
  • 12
    • 0041529925 scopus 로고    scopus 로고
    • Influence of mianserin on the activity of some hypotensive drugs in spontaneously hypertensive rats
    • Górska D, Andrzejczak D: Influence of mianserin on the activity of some hypotensive drugs in spontaneously hypertensive rats. Pol J Pharmacol, 2003, 55, 409-417.
    • (2003) Pol J Pharmacol , vol.55 , pp. 409-417
    • Górska, D.1    Andrzejczak, D.2
  • 13
    • 0041837595 scopus 로고    scopus 로고
    • Long-term treatment with nebivolol im-proves arterial reactivity and reduces ventricular hyper-trophy in spontaneously hypertensive rats
    • Guerrero E, Voces F, Ardanaz N, Montero MJ, Arévalo M, Sevilla MA: Long-term treatment with nebivolol im-proves arterial reactivity and reduces ventricular hyper-trophy in spontaneously hypertensive rats. J Cardiovasc Pharmacol, 2003, 42, 348-355.
    • (2003) J Cardiovasc Pharmacol , vol.42 , pp. 348-355
    • Guerrero, E.1    Voces, F.2    Ardanaz, N.3    Montero, M.J.4    Arévalo, M.5    Sevilla, M.A.6
  • 14
    • 29144477347 scopus 로고    scopus 로고
    • Cardiovascular effects of nebivolol in spontaneously hypertensive rats persist after treatment withdrawal
    • Guerrero EI, Ardanaz N, Sevilla MA, Arévalo MA, Montero MJ: Cardiovascular effects of nebivolol in spontaneously hypertensive rats persist after treatment withdrawal. J Hypertens, 2006, 24, 151-158.
    • (2006) J Hypertens , vol.24 , pp. 151-158
    • Guerrero, E.I.1    Ardanaz, N.2    Sevilla, M.A.3    Arévalo, M.A.4    Montero, M.J.5
  • 15
    • 46849117086 scopus 로고    scopus 로고
    • Different pharmacological properties of two enantiomers in a unique beta-blocker, nebivolol
    • Ignarro LJ: Different pharmacological properties of two enantiomers in a unique beta-blocker, nebivolol. Cardio-vasc Ther, 2008, 26, 115-134.
    • (2008) Cardio-vasc Ther , vol.26 , pp. 115-134
    • Ignarro, L.J.1
  • 16
    • 80052399313 scopus 로고    scopus 로고
    • Experimental evidences of nitric oxide-dependent vasodilatory activity of nebivolol, a third-generation beta-blocker
    • Ignarro LJ: Experimental evidences of nitric oxide-dependent vasodilatory activity of nebivolol, a third-generation beta-blocker. Blood Press Suppl, 2004, 1, 2-16.
    • (2004) Blood Press Suppl , vol.1 , pp. 2-16
    • Ignarro, L.J.1
  • 17
    • 0024202991 scopus 로고
    • Effects of antihypertensives on plasma lipids and lipoprotein metabolism
    • Krone W, Nägele H: Effects of antihypertensives on plasma lipids and lipoprotein metabolism. Am Heart J, 1988, 116, 1729-1734.
    • (1988) Am Heart J , vol.116 , pp. 1729-1734
    • Krone, W.1    Nägele, H.2
  • 18
    • 6344237308 scopus 로고    scopus 로고
    • Pharmacological mechanisms of clinically favorable properties of a selec-tive -adrenoceptor antagonist, nebivolol
    • Kuroedov A, Cosentino F, Lüscher TF: Pharmacological mechanisms of clinically favorable properties of a selec-tive -adrenoceptor antagonist, nebivolol. Cardiovasc Drug Rev, 2004, 22, 155-168.
    • (2004) Cardiovasc Drug Rev , vol.22 , pp. 155-168
    • Kuroedov, A.1    Cosentino, F.2    Lüscher, T.F.3
  • 19
    • 33745967267 scopus 로고    scopus 로고
    • Mechanisms underlying nebivolol-induced endothelial nitric oxide synthase acti-vation in human umbilical vein endothelial cells
    • Ladage D, Brixius K, Hoyer H, Steingen C, Wesseling A, Malan D, Bloch W et al.: Mechanisms underlying nebivolol-induced endothelial nitric oxide synthase acti-vation in human umbilical vein endothelial cells. Clin Exp Pharmacol Physiol, 2006, 33, 720-724.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , pp. 720-724
    • Ladage, D.1    Brixius, K.2    Hoyer, H.3    Steingen, C.4    Wesseling, A.5    Malan, D.6    Bloch, W.7
  • 20
    • 33747809601 scopus 로고    scopus 로고
    • Effect of nebivolol on endothelial nitric ox-ide and peroxynitrite release in hypertensive animals: Role of antioxidant activity
    • Mason RP, Kubant R, Jacob RF, Walter MF, Boychuk B, Malinski T: Effect of nebivolol on endothelial nitric ox-ide and peroxynitrite release in hypertensive animals: Role of antioxidant activity. J Cardiovasc Pharmacol, 2006,48,862-869.
    • (2006) J Cardiovasc Pharmacol , vol.48 , pp. 862-869
    • Mason, R.P.1    Kubant, R.2    Jacob, R.F.3    Walter, M.F.4    Boychuk, B.5    Malinski, T.6
  • 21
    • 58149478344 scopus 로고    scopus 로고
    • Proinflammation and hypertension: A population-based study
    • Mauno V, Hannu K, Esko K: Proinflammation and hypertension: a population-based study. Mediators Inflamm, 2008,2008,619-704.
    • (2008) Mediators Inflamm , vol.2008 , pp. 619-704
    • Mauno, V.1    Hannu, K.2    Esko, K.3
  • 22
    • 0037390324 scopus 로고    scopus 로고
    • Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells
    • Mollnau H, Schulz E, Daiber A, Baldus S, Oelze M, August M, Wendt M et al.: Nebivolol prevents vascular NOS III uncoupling in experimental hyperlipidemia and inhibits NADPH oxidase activity in inflammatory cells. Arterioscler Thromb Vasc Biol, 2003, 23, 615-621.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 615-621
    • Mollnau, H.1    Schulz, E.2    Daiber, A.3    Baldus, S.4    Oelze, M.5    August, M.6    Wendt, M.7
  • 24
    • 0024211087 scopus 로고
    • The receptor binding profile of the new anti hypertensive agent nebivolol and its stereoisomers compared with various beta-adrenergic blockers
    • Pauwels PJ, Gommeren W, Van Lommen G, Janssen PA, Leysen JE: The receptor binding profile of the new anti hypertensive agent nebivolol and its stereoisomers compared with various beta-adrenergic blockers. Mol Pharmacol, 1988, 34, 843-851.
    • (1988) Mol Pharmacol , vol.34 , pp. 843-851
    • Pauwels, P.J.1    Gommeren, W.2    van Lommen, G.3    Janssen, P.A.4    Leysen, J.E.5
  • 25
    • 33645472417 scopus 로고    scopus 로고
    • Effect of treatment with nebivolol on parameters of oxidative stress in type 2 diabetics with mild to moderate hypertension
    • Peter P, Martin U, Sharma A, Dunne F: Effect of treatment with nebivolol on parameters of oxidative stress in type 2 diabetics with mild to moderate hypertension. J Clin Pharm Ther, 2006, 31, 153-159.
    • (2006) J Clin Pharm Ther , vol.31 , pp. 153-159
    • Peter, P.1    Martin, U.2    Sharma, A.3    Dunne, F.4
  • 27
    • 0038170610 scopus 로고    scopus 로고
    • The combination of nebivolol plus pravastatin is associated with a more beneficial metabolic profile compared to that of atenolol plus pravastatin in hypertensive patients with dyslipidemia: A pilot study
    • Rizos E, Bairaktari E, Kostoula A, Hasiotis G, Achimastos A, Ganotakis E, Elisaf M et al.: The combination of nebivolol plus pravastatin is associated with a more beneficial metabolic profile compared to that of atenolol plus pravastatin in hypertensive patients with dyslipidemia: a pilot study. J Cardiovasc Pharmacol Ther, 2003, 8, 127-134.
    • (2003) J Cardiovasc Pharmacol Ther , vol.8 , pp. 127-134
    • Rizos, E.1    Bairaktari, E.2    Kostoula, A.3    Hasiotis, G.4    Achimastos, A.5    Ganotakis, E.6    Elisaf, M.7
  • 28
    • 34247136835 scopus 로고    scopus 로고
    • Vascular inflammation in hypertension and diabetes: Molecular mechanisms and therapeutic interventions
    • Savoia C, Schiffrin EL: Vascular inflammation in hypertension and diabetes: molecular mechanisms and therapeutic interventions. Clin Sci (Lond), 2007, 112, 375-384.
    • (2007) Clin Sci (Lond) , vol.112 , pp. 375-384
    • Savoia, C.1    Schiffrin, E.L.2
  • 29
    • 52249121952 scopus 로고    scopus 로고
    • Effects of the vasodilating beta-blocker nebivolol on smoking-induced endothelial dysfunction in young healthy volunteers
    • Schmidt AC, Flick B, Jahn E, Bramlage P: Effects of the vasodilating beta-blocker nebivolol on smoking-induced endothelial dysfunction in young healthy volunteers. Vasc Health Risk Manag, 2008, 4, 909-915.
    • (2008) Vasc Health Risk Manag , vol.4 , pp. 909-915
    • Schmidt, A.C.1    Flick, B.2    Jahn, E.3    Bramlage, P.4
  • 31
    • 0031436734 scopus 로고    scopus 로고
    • Nebivolol vs enalapril in the treatment of essential hypertension: A double-blind randomised trial
    • Van Nueten L, Schelling A, Vertommen C, Dupont AG, Robertson JI: Nebivolol vs enalapril in the treatment of essential hypertension: a double-blind randomised trial. J Hum Hypertens, 1997, 11, 813-819.
    • (1997) J Hum Hypertens , vol.11 , pp. 813-819
    • van Nueten, L.1    Schelling, A.2    Vertommen, C.3    Dupont, A.G.4    Robertson, J.I.5
  • 32
    • 33746990729 scopus 로고    scopus 로고
    • Nebivolol: A third-generation beta-adrenergic blocker
    • Veverka A, Nuzum DS, Jolly JL: Nebivolol: a third-generation beta-adrenergic blocker. Ann Pharmacother, 2006,40,1353-1360.
    • (2006) Ann Pharmacother , vol.40 , pp. 1353-1360
    • Veverka, A.1    Nuzum, D.S.2    Jolly, J.L.3
  • 34
    • 39749203492 scopus 로고    scopus 로고
    • Major differences in gene expression in human coronary smooth muscle cells after nebivolol or metoprolol treatment
    • Wolf SC, Sauter G, Jobst J, Kempf VA, Risler T, Brehm BR: Major differences in gene expression in human coronary smooth muscle cells after nebivolol or metoprolol treatment. Int J Cardiol, 2008, 125, 4-10.
    • (2008) Int J Cardiol , vol.125 , pp. 4-10
    • Wolf, S.C.1    Sauter, G.2    Jobst, J.3    Kempf, V.A.4    Risler, T.5    Brehm, B.R.6
  • 35
    • 33847066767 scopus 로고    scopus 로고
    • Influence of nebivolol and metoprolol on inflammatory mediators in human coronary endothelial or smooth muscle cells. Effects on neointima formation after balloon denudation in carotid arteries of rats treated with nebivolol
    • Wolf SC, Sauter G, Preyer M, Poerner T, Kempf VA, Risler T, Brehm BR: Influence of nebivolol and metoprolol on inflammatory mediators in human coronary endothelial or smooth muscle cells. Effects on neointima formation after balloon denudation in carotid arteries of rats treated with nebivolol. Cell Physiol Biochem, 2007, 19, 129-136.
    • (2007) Cell Physiol Biochem , vol.19 , pp. 129-136
    • Wolf, S.C.1    Sauter, G.2    Preyer, M.3    Poerner, T.4    Kempf, V.A.5    Risler, T.6    Brehm, B.R.7
  • 37
    • 50249123892 scopus 로고    scopus 로고
    • The role of inflammatory cytokines in endothelial dysfunction
    • Zhang C: The role of inflammatory cytokines in endothelial dysfunction. Basic Res Cardiol, 2008, 103, 398-406.
    • (2008) Basic Res Cardiol , vol.103 , pp. 398-406
    • Zhang, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.